Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites

Central dogma rates and the trade-off between precision and economy in gene expression

(2019) Jean Hausser et al.   Nature Communications

Transcriptome and histone epigenome of Plasmodium vivax salivary-gland sporozoites point to tight regulatory control and mechanisms for liver-stage differentiation in relapsing malaria

(2019) Ivo Muller et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Plasmodium yoelii S4/CelTOS is important for sporozoite gliding motility and cell traversal

(2018) Ryan W.J. Steel et al.   CELLULAR MICROBIOLOGY

StPeter: Seamless Label-Free Quantification with the Trans-Proteomic Pipeline

(2018) Michael R. Hoopmann et al.   JOURNAL OF PROTEOME RESEARCH

A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection

(2018) Gigliola Zanghì et al.   Cell Reports

Plasmodium Parasites Viewed through Proteomics

(2018) Kristian E. Swearingen et al.   TRENDS IN PARASITOLOGY

Vector biology meets disease control: using basic research to fight vector-borne diseases

(2018) W. Robert Shaw et al.   Nature Microbiology

The Development of Whole Sporozoite Vaccines for Plasmodium falciparum Malaria

(2018) Leslie S. Itsara et al.   Frontiers in Immunology

ALBA4 modulates its stage-specific interactions and specific mRNA fates during Plasmodium yoelii growth and transmission

(2017) Elyse E. Muñoz et al.   MOLECULAR MICROBIOLOGY

Translational Control in the Latency of Apicomplexan Parasites

(2017) Michael J. Holmes et al.   TRENDS IN PARASITOLOGY

Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development

(2017) Cui Zhang et al.   mBio

A Novel and Conserved Plasmodium Sporozoite Membrane Protein SPELD is Required for Maturation of Exo-erythrocytic Forms

(2017) Faisal Mohammed Abdul Al-Nihmi et al.   Scientific Reports

Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice

(2017) Annie S.P. Yang et al.   Cell Reports

Proteogenomic analysis of the total and surface-exposed proteomes of Plasmodium vivax salivary gland sporozoites

(2017) Kristian E. Swearingen et al.   PLoS Neglected Tropical Diseases

Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes

(2017) Eliana Real et al.   Nature Microbiology

Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children

(2016) Ally Olotu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Integrated transcriptomic and proteomic analyses ofP. falciparumgametocytes: molecular insight into sex-specific processes and translational repression

(2016) Edwin Lasonder et al.   NUCLEIC ACIDS RESEARCH

PlasmoSEP: Predicting surface-exposed proteins on the malaria parasite using semisupervised self-training and expert-annotated data

(2016) Yasser El-Manzalawy et al.   PROTEOMICS

UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages

(2016) Min Zhang et al.   PLoS Pathogens

Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics

(2016) Kristian E. Swearingen et al.   PLoS Pathogens

Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

(2016) John R Jimah et al.   eLife

Translational Control of UIS4 Protein of the Host-Parasite Interface Is Mediated by the RNA Binding Protein Puf2 in Plasmodium berghei Sporozoites

(2016) Patrícia A. G. C. Silva et al.   PLoS One

The innate and adaptive response to mosquito saliva andPlasmodiumsporozoites in the skin

(2015) Christine S. Hopp et al.   Annals of the New York Academy of Sciences

Malaria Sporozoites Traverse Host Cells within Transient Vacuoles

(2015) Veronica Risco-Castillo et al.   Cell Host & Microbe

Trans-Proteomic Pipeline, a standardized data processing pipeline for large-scale reproducible proteomics informatics

(2015) Eric W. Deutsch et al.   Proteomics Clinical Applications

Longitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognition

(2015) Christine S Hopp et al.   eLife

Translational regulation during stage transitions in malaria parasites

(2014) Liwang Cui et al.   Annals of the New York Academy of Sciences

A comprehensive evaluation of rodent malaria parasite genomes and gene expression

(2014) Thomas D Otto et al.   BMC BIOLOGY

Characterization ofPlasmodiumdevelopmental transcriptomes inAnopheles gambiaemidgut reveals novel regulators of malaria transmission

(2014) Karolina A. Akinosoglou et al.   CELLULAR MICROBIOLOGY

The Plasmodium protein P113 supports efficient sporozoite to liver stage conversion in vivo

(2014) Vittoria Offeddu et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Post-transcriptional silencing ofUIS4inPlasmodium bergheisporozoites is important for host switch

(2014) Olivier Silvie et al.   MOLECULAR MICROBIOLOGY

VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases

(2014) Gloria I. Giraldo-Calderón et al.   NUCLEIC ACIDS RESEARCH

Perturbations ofPlasmodium Puf2 expression and RNA-seq of Puf2-deficient sporozoites reveal a critical role in maintaining RNA homeostasis and parasite transmissibility

(2013) Scott E. Lindner et al.   CELLULAR MICROBIOLOGY

Plasmodium yoeliiinhibitor of cysteine proteases is exported to exomembrane structures and interacts with yoelipain-2 during asexual blood-stage development

(2013) Ying Pei et al.   CELLULAR MICROBIOLOGY

Type II Fatty Acid Biosynthesis Is Essential for Plasmodium falciparum Sporozoite Development in the Midgut of Anopheles Mosquitoes

(2013) Ben C. L. van Schaijk et al.   EUKARYOTIC CELL

Plasmodium berghei Sporozoites Acquire Virulence and Immunogenicity during Mosquito Hemocoel Transit

(2013) Yuko Sato et al.   INFECTION AND IMMUNITY

Combining Results of Multiple Search Engines in Proteomics

(2013) David Shteynberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Total and Putative Surface Proteomics of Malaria Parasite Salivary Gland Sporozoites

(2013) Scott E. Lindner et al.   MOLECULAR & CELLULAR PROTEOMICS

ThePlasmodiumtranslocon of exported proteins (PTEX) component thioredoxin-2 is important for maintaining normal blood-stage growth

(2013) Kathryn Matthews et al.   MOLECULAR MICROBIOLOGY

Enzymes involved in plastid-targeted phosphatidic acid synthesis are essential forPlasmodium yoeliiliver-stage development

(2013) Scott E. Lindner et al.   MOLECULAR MICROBIOLOGY

Puf Mediates Translation Repression of Transmission-Blocking Vaccine Candidates in Malaria Parasites

(2013) Jun Miao et al.   PLoS Pathogens

A rapid and scalable density gradient purification method for Plasmodium sporozoites

(2012) Mark Kennedy et al.   MALARIA JOURNAL

Comet: An open-source MS/MS sequence database search tool

(2012) Jimmy K. Eng et al.   PROTEOMICS

Evaluation of Normalization Methods on GeLC-MS/MS Label-Free Spectral Counting Data to Correct for Variation during Proteomic Workflows

(2011) Emine Gokce et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Plasmodium Cysteine Repeat Modular Proteins 3 and 4 are essential for malaria parasite transmission from the mosquito to the host

(2011) Bruno Douradinha et al.   MALARIA JOURNAL

The Puf-Family RNA-Binding Protein Puf2 Controls Sporozoite Conversion to Liver Stages in the Malaria Parasite

(2011) Katja Müller et al.   PLoS One

Transition of Plasmodium Sporozoites into Liver Stage-Like Forms Is Regulated by the RNA Binding Protein Pumilio

(2011) Carina S. S. Gomes-Santos et al.   PLoS Pathogens

Refinements to Label Free Proteome Quantitation: How to Deal with Peptides Shared by Multiple Proteins

(2010) Ying Zhang et al.   ANALYTICAL CHEMISTRY

Perinuclear P granules are the principal sites of mRNA export in adult C. elegans germ cells

(2010) U. Sheth et al.   DEVELOPMENT

ThePlasmodiumeukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands

(2010) Min Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Universal Features of Post-Transcriptional Gene Regulation Are Critical for Plasmodium Zygote Development

(2010) Gunnar R. Mair et al.   PLoS Pathogens

ProteoWizard: open source software for rapid proteomics tools development

(2008) Darren Kessner et al.   BIOINFORMATICS

The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites

(2008) Cristina K. Moreira et al.   CELLULAR MICROBIOLOGY

Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

(2008) Ashley M. Vaughan et al.   CELLULAR MICROBIOLOGY

Distinct Malaria Parasite Sporozoites Reveal Transcriptional Changes That Cause Differential Tissue Infection Competence in the Mosquito Vector and Mammalian Host

(2008) S. A. Mikolajczak et al.   MOLECULAR AND CELLULAR BIOLOGY

PlasmoDB: a functional genomic database for malaria parasites

(2008) C. Aurrecoechea et al.   NUCLEIC ACIDS RESEARCH

The Transmembrane Isoform of Plasmodium falciparum MAEBL Is Essential for the Invasion of Anopheles Salivary Glands

(2008) Fabian E. Saenz et al.   PLoS One

Malaria: some considerations regarding parasite productivity

(2008) Ronald Rosenberg   TRENDS IN PARASITOLOGY

Proteomic Profiling of Plasmodium Sporozoite Maturation Identifies New Proteins Essential for Parasite Development and Infectivity

(2008) Edwin Lasonder et al.   PLoS Pathogens