UIS2: A Unique Phosphatase Required for the Development of Plasmodium Liver Stages

The catalytic role of the M2 metal ion in PP2Cα

(2015) Chang Pan et al.   Scientific Reports

Genome-wide Functional Analysis of Plasmodium Protein Phosphatases Reveals Key Regulators of Parasite Development and Differentiation

(2014) David S. Guttery et al.   Cell Host & Microbe

Protein phosphatase PP1/GLC7 interaction domain in yeast eIF2  bypasses targeting subunit requirement for eIF2  dephosphorylation

(2014) M. Rojas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibitors of eIF2α Dephosphorylation Slow Replication and Stabilize Latency in Toxoplasma gondii

(2013) Christian Konrad et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Eukaryotic initiation factor 2  phosphorylation mediates fetal hemoglobin induction through a post-transcriptional mechanism

(2013) C. K. Hahn et al.   BLOOD

Perturbations ofPlasmodium Puf2 expression and RNA-seq of Puf2-deficient sporozoites reveal a critical role in maintaining RNA homeostasis and parasite transmissibility

(2013) Scott E. Lindner et al.   CELLULAR MICROBIOLOGY

Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site

(2013) Chang Pan et al.   Scientific Reports

Translational Control in Plasmodium and Toxoplasma Parasites

(2012) Min Zhang et al.   EUKARYOTIC CELL

PK4, a eukaryotic initiation factor 2 (eIF2 ) kinase, is essential for the development of the erythrocytic cycle of Plasmodium

(2012) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Puf-Family RNA-Binding Protein Puf2 Controls Sporozoite Conversion to Liver Stages in the Malaria Parasite

(2011) Katja Müller et al.   PLoS One

Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis

(2011) P. Tsaytler et al.   SCIENCE

Transition of Plasmodium Sporozoites into Liver Stage-Like Forms Is Regulated by the RNA Binding Protein Pumilio

(2011) Carina S. S. Gomes-Santos et al.   PLoS Pathogens

The Puf-family RNA-binding protein PfPuf2 regulates sexual development and sex differentiation in the malaria parasite Plasmodium falciparum

(2010) J. Miao et al.   JOURNAL OF CELL SCIENCE

ThePlasmodiumeukaryotic initiation factor-2α kinase IK2 controls the latency of sporozoites in the mosquito salivary glands

(2010) Min Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SAP1 is a critical post-transcriptional regulator of infectivity in malaria parasite sporozoite stages

(2010) Ahmed S. I. Aly et al.   MOLECULAR MICROBIOLOGY

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Clonal Conditional Mutagenesis in Malaria Parasites

(2009) Audrey Combe et al.   Cell Host & Microbe

Docking Motif-Guided Mapping of the Interactome of Protein Phosphatase-1

(2009) Annick Hendrickx et al.   CHEMISTRY & BIOLOGY

Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development

(2009) Heather P. Harding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The protein-phosphatome of the human malaria parasite Plasmodium falciparum

(2008) Jonathan M Wilkes et al.   BMC GENOMICS

Translation Regulation by Eukaryotic Initiation Factor-2 Kinases in the Development of Latent Cysts inToxoplasma gondii

(2008) Jana Narasimhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Malaria Parasite Sporozoites Reveal Transcriptional Changes That Cause Differential Tissue Infection Competence in the Mosquito Vector and Mammalian Host

(2008) S. A. Mikolajczak et al.   MOLECULAR AND CELLULAR BIOLOGY

A combined transcriptome and proteome survey of malaria parasite liver stages

(2008) A. S. Tarun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic Profiling of Plasmodium Sporozoite Maturation Identifies New Proteins Essential for Parasite Development and Infectivity

(2008) Edwin Lasonder et al.   PLoS Pathogens