Research progress on the multidrug resistance mechanisms of osteosarcoma chemotherapy and reversal

Targeting Glutathione-S Transferase Enzymes in Musculoskeletal Sarcomas: A Promising Therapeutic Strategy

(2015) Michela Pasello et al.   Analytical Cellular Pathology

Prevention of multidrug resistance (MDR) in osteosarcoma by NSC23925

(2014) X Yang et al.   BRITISH JOURNAL OF CANCER

mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels

(2014) Kaveh M Goudarzi et al.   CANCER BIOLOGY & THERAPY

Effect of variation of ABCB1 and GSTP1 on osteosarcoma survival after chemotherapy

(2014) J.Z. Li et al.   GENETICS AND MOLECULAR RESEARCH

Prognostic value of microRNA-223/epithelial cell transforming sequence 2 signaling in patients with osteosarcoma

(2014) Haoshaqiang Zhang et al.   HUMAN PATHOLOGY

Temsirolimus combined with cisplatin or bevacizumab is active in osteosarcoma models

(2014) Emmy D.G. Fleuren et al.   INTERNATIONAL JOURNAL OF CANCER

miR-33a is up-regulated in chemoresistant osteosarcoma and promotes osteosarcoma cell resistance to cisplatin by down-regulating TWIST

(2014) Yong Zhou et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

APEX1 Gene Amplification and Its Protein Overexpression in Osteosarcoma: Correlation with Recurrence, Metastasis, and Survival

(2014) Jilong Yang et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

ERCC polymorphisms and prognosis of patients with osteosarcoma

(2014) Jinsong Li et al.   TUMOR BIOLOGY

High-mobility group nucleosome-binding domain 5 increases drug resistance in osteosarcoma through upregulating autophagy

(2014) Chaoqun Yang et al.   TUMOR BIOLOGY

Drug Resistance in Cancer: An Overview

(2014) Genevieve Housman et al.   Cancers

Glutathione S-transferase P1 and DNA Polymorphisms with the Response to Chemotherapy and the Prognosis of Bone Tumor

(2013) Li-Min Yang et al.   Asian Pacific Journal of Cancer Prevention

Association of Four ERCC1 and ERCC2 SNPs with Survival of Bone Tumour Patients

(2013) Ting Hao et al.   Asian Pacific Journal of Cancer Prevention

The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis

(2013) Zeze Fu et al.   BMC CANCER

VEGFR, RET, and RAF/MEK/ERK Pathway Take Part in the Inhibition of Osteosarcoma MG63 Cells with Sorafenib Treatment

(2013) Jiong Mei et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

The P-Glycoprotein Transport System and Cardiovascular Drugs

(2013) Jeffrey D. Wessler et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A systematic review of p53 as a biomarker of survival in patients with osteosarcoma

(2013) Hai-Liang Fu et al.   TUMOR BIOLOGY

Role of Topoisomerases in Pediatric High Grade Osteosarcomas: TOP2A Gene Is One of the Unique Molecular Biomarkers of Chemoresponse

(2013) Aurelia Nguyen et al.   Cancers

Increased expression and function of P-glycoprotein in peripheral blood CD56+ cells is associated with the chemoresistance of non-small-cell lung cancer

(2012) Li Han et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase B (PKB) and PKC signaling pathways

(2012) Ching-Lung Liao et al.   FOOD AND CHEMICAL TOXICOLOGY

Germline genetic polymorphisms may influence chemotherapy response and disease outcome in osteosarcoma

(2011) Rachael E. Windsor et al.   CANCER

Expressions of p53, c-MYC, BCL-2 and apoptotic index in human osteosarcoma and their correlations with prognosis of patients

(2011) Xing Wu et al.   Cancer Epidemiology

Revisiting the ABCs of Multidrug Resistance in Cancer Chemotherapy

(2011) Amit K. Tiwari et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

P-glycoprotein binds to ezrin at amino acid residues 149-242 in the FERM domain and plays a key role in the multidrug resistance of human osteosarcoma

(2011) Daria Brambilla et al.   INTERNATIONAL JOURNAL OF CANCER

Curcumin-loaded γ-cyclodextrin liposomal nanoparticles as delivery vehicles for osteosarcoma

(2011) Santosh S. Dhule et al.   Nanomedicine-Nanotechnology Biology and Medicine

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells

(2011) G Bulut et al.   ONCOGENE

Nucleotide excision repair gene variants and association with survival in osteosarcoma patients treated with neoadjuvant chemotherapy

(2011) P Biason et al.   PHARMACOGENOMICS JOURNAL

Advantages of bioluminescence imaging to follow siRNA or chemotherapeutic treatments in osteosarcoma preclinical models

(2010) J Rousseau et al.   CANCER GENE THERAPY

CD117 and Stro-1 Identify Osteosarcoma Tumor-Initiating Cells Associated with Metastasis and Drug Resistance

(2010) Amit S. Adhikari et al.   CANCER RESEARCH

Zoledronic Acid Potentiates mTOR Inhibition and Abolishes the Resistance of Osteosarcoma Cells to RAD001 (Everolimus): Pivotal Role of the Prenylation Process

(2010) G. Moriceau et al.   CANCER RESEARCH

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells

(2010) Bo Song et al.   Molecular Cancer

Inhibition of ABCB1 (MDR1) Expression by an siRNA Nanoparticulate Delivery System to Overcome Drug Resistance in Osteosarcoma

(2010) Michiro Susa et al.   PLoS One

Protein kinase C regulates ezrin-radixin-moesin phosphorylation in canine osteosarcoma cells

(2010) S.-H. Hong et al.   Veterinary and Comparative Oncology

The effect of resistance-related proteins on the prognosis and survival of patients with osteosarcoma: an immunohistochemical analysis

(2009) Harzem Ozger   Acta Orthopaedica et Traumatologica Turcica

Multiple pathways are involved in drug resistance to doxorubicin in an osteosarcoma cell line

(2009) Thangarajan Rajkumar et al.   ANTI-CANCER DRUGS

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

Cancer Stem Cells: A New Paradigm for Understanding Tumor Growth and Progression and Drug Resistance

(2009) Rosaria Gangemi et al.   CURRENT MEDICINAL CHEMISTRY

Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment

(2009) Riccardo Di Fiore et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Methotrexate in Pediatric Osteosarcoma: Response and Toxicity in Relation to Genetic Polymorphisms and Dihydrofolate Reductase and Reduced Folate Carrier 1 Expression

(2009) Ana Patiño-García et al.   JOURNAL OF PEDIATRICS

Sorafenib blocks tumour growth, angiogenesis and metastatic potential in preclinical models of osteosarcoma through a mechanism potentially involving the inhibition of ERK1/2, MCL-1 and ezrin pathways

(2009) Ymera Pignochino et al.   Molecular Cancer

Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells

(2009) B Song et al.   ONCOGENE

Resistance of stem-like cells from neuroblastoma cell lines to commonly used chemotherapeutic agents

(2009) Sharada D. Vangipuram et al.   PEDIATRIC BLOOD & CANCER

Common variations in ERCC2 are associated with response to cisplatin chemotherapy and clinical outcome in osteosarcoma patients

(2009) D Caronia et al.   PHARMACOGENOMICS JOURNAL

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Overcoming Glutathione S-Transferase P1-Related Cisplatin Resistance in Osteosarcoma

(2008) M. Pasello et al.   CANCER RESEARCH

Osteosarcoma: The Addition of Muramyl Tripeptide to Chemotherapy Improves Overall Survival—A Report From the Children's Oncology Group

(2008) Paul A. Meyers et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology

Detection and Characterization of CD133+ Cancer Stem Cells in Human Solid Tumours

(2008) Virginia Tirino et al.   PLoS One