Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens

Rapid Expansion of Human Epithelial Stem Cells Suitable for Airway Tissue Engineering

(2016) Colin R. Butler et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3-MYC Interactions as a Target in Pancreatic Cancer

(2016) N. Beglyarova et al.   CLINICAL CANCER RESEARCH

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

(2016) Aaron N Hata et al.   NATURE MEDICINE

Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect

(2016) Guido Veit et al.   PLOS BIOLOGY

The ethics of stem cells revisited

(2015) Iñigo de Miguel-Beriain   ADVANCED DRUG DELIVERY REVIEWS

Developing in vitro models of human ductal carcinoma in situ from primary tissue explants

(2015) Daniel D. Brown et al.   BREAST CANCER RESEARCH AND TREATMENT

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

(2015) Sylvia F. Boj et al.   CELL

CRISPR–Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18

(2015) H W Chu et al.   GENE THERAPY

Ovarian and cervical cancer patient derived xenografts: The past, present, and future

(2015) Jonathan D. Boone et al.   GYNECOLOGIC ONCOLOGY

Sequential cancer mutations in cultured human intestinal stem cells

(2015) Jarno Drost et al.   NATURE

An ecosystem of cancer cell line factories to support a cancer dependency map

(2015) Jesse S. Boehm et al.   NATURE REVIEWS GENETICS

Patient-derived bladder cancer xenografts: a systematic review

(2015) Carina Bernardo et al.   Translational Research

Pseudo-immortalization of postnatal cochlear progenitor cells yields a scalable cell line capable of transcriptionally regulating mature hair cell genes

(2015) Brandon J. Walters et al.   Scientific Reports

Using induced pluripotent stem cells as a tool for modelling carcinogenesis

(2015) Emma L Curry   World Journal of Stem Cells

Methods of induced pluripotent stem cells for clinical application

(2015) Tomohisa Seki   World Journal of Stem Cells

Cancer Cell Lines for Drug Discovery and Development

(2014) J. L. Wilding et al.   CANCER RESEARCH

Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment

(2014) D. Herrmann et al.   CARCINOGENESIS

Organoid cultures for the analysis of cancer phenotypes

(2014) Norman Sachs et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A model system to analyse the ability of human keratinocytes to form hair follicles

(2014) Rajesh L. Thangapazham et al.   EXPERIMENTAL DERMATOLOGY

Mammary stem cells have myoepithelial cell properties

(2014) Michael D. Prater et al.   NATURE CELL BIOLOGY

Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture

(2014) Xingnan Li et al.   NATURE MEDICINE

Patient-derived models of acquired resistance can identify effective drug combinations for cancer

(2014) Adam S. Crystal et al.   SCIENCE

Radiation Induces Diffusible Feeder Cell Factor(s) That Cooperate with ROCK Inhibitor to Conditionally Reprogram and Immortalize Epithelial Cells

(2013) Nancy Palechor-Ceron et al.   AMERICAN JOURNAL OF PATHOLOGY

Lessons from the Cancer Genome

(2013) Levi A. Garraway et al.   CELL

Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites

(2013) Rajesh L. Thangapazham et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Clinical Relevance of Cancer Cell Lines

(2013) J.-P. Gillet et al.   JNCI-Journal of the National Cancer Institute

Patient-derived xenografts, the cancer stem cell paradigm and cancer pathobiology in the 21st century

(2013) Samuel A Williams et al.   LABORATORY INVESTIGATION

Issues to be considered when studying cancer in vitro

(2012) Beata Čunderlíková   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Patient-derived tumour xenografts as models for oncology drug development

(2012) John J. Tentler et al.   Nature Reviews Clinical Oncology

Use of Reprogrammed Cells to Identify Therapy for Respiratory Papillomatosis

(2012) Hang Yuan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells

(2012) F. A. Suprynowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preclinical models in radiation oncology

(2012) Jenna Kahn et al.   Radiation Oncology

ROCK Inhibitor and Feeder Cells Induce the Conditional Reprogramming of Epithelial Cells

(2011) Xuefeng Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Cutaneous Human Papillomavirus Type 38 E7 Regulates Actin Cytoskeleton Structure for Increasing Cell Proliferation through CK2 and the Eukaryotic Elongation Factor 1A

(2011) J. Yue et al.   JOURNAL OF VIROLOGY

Chemically defined conditions for human iPSC derivation and culture

(2011) Guokai Chen et al.   NATURE METHODS

Patient-derived human tumour tissue xenografts in immunodeficient mice: a systematic review

(2010) Ketao Jin et al.   Clinical & Translational Oncology

Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor

(2010) Sandra Chapman et al.   JOURNAL OF CLINICAL INVESTIGATION

Efficient Procurement of Epithelial Stem Cells from Human Tissue Specimens Using a Rho-Associated Protein Kinase Inhibitor Y-27632

(2009) Atsushi Terunuma et al.   TISSUE ENGINEERING PART A