c-Myc shuttled by tumour-derived extracellular vesicles promotes lung bronchial cell proliferation through miR-19b and miR-92a

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(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Hypoxic Lung-Cancer-Derived Extracellular Vesicle MicroRNA-103a Increases the Oncogenic Effects of Macrophages by Targeting PTEN

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The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications

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mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis

(2017) Cristina Borzi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1

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Oncogenic transformation of lung cells results in distinct exosome protein profile similar to the cell of origin

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Lung cancer–associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell–immune cell cross-talk

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Concomitant underexpression of TGFBR2 and overexpression of hTERT are associated with poor prognosis in cervical cancer

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Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

STAT3-regulated exosomal miR-21 promotes angiogenesis and is involved in neoplastic processes of transformed human bronchial epithelial cells

(2016) Yi Liu et al.   CANCER LETTERS

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(2016) Theresa L. Whiteside   JOURNAL OF CLINICAL INVESTIGATION

Extracellular vesicle isolation and characterization: toward clinical application

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(2016) Nobuyoshi Kosaka et al.   JOURNAL OF CLINICAL INVESTIGATION

Lung cancer exosomes as drivers of epithelial mesenchymal transition

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Novel method to detect microRNAs using chip-based QuantStudio 3D digital PCR

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Recent advances of microRNA-based molecular diagnostics to reduce false-positive lung cancer imaging

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Non–Small-Cell Lung Cancer: Role of the Immune System and Potential for Immunotherapy

(2015) David P. Carbone et al.   Journal of Thoracic Oncology

Towards a molecular understanding of microRNA-mediated gene silencing

(2015) Stefanie Jonas et al.   NATURE REVIEWS GENETICS

Targeting the TGFβ pathway for cancer therapy

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Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Clinical Utility of a Plasma-Based miRNA Signature Classifier Within Computed Tomography Lung Cancer Screening: A Correlative MILD Trial Study

(2014) Gabriella Sozzi et al.   JOURNAL OF CLINICAL ONCOLOGY

TGFβ: A player on multiple fronts in the tumor microenvironment

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Assessment of Circulating microRNAs in Plasma of Lung Cancer Patients

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miRNA 17 Family Regulates Cisplatin-Resistant and Metastasis by Targeting TGFbetaR2 in NSCLC

(2014) Zeyong Jiang et al.   PLoS One

Mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction

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The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

(2013) E Mogilyansky et al.   CELL DEATH AND DIFFERENTIATION

Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations

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MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A transcriptionally active pRb–E2F1–P/CAF signaling pathway is central to TGFβ-mediated apoptosis

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MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer

(2011) Mattia Boeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Myc-miR-17 92 Axis Blunts TGF  Signaling and Production of Multiple TGF -Dependent Antiangiogenic Factors

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Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Tumor Stroma in Cancer Progression and Prognosis: Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer

(2010) Roy M. Bremnes et al.   Journal of Thoracic Oncology

Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR)

(2010) Evan M. Kroh et al.   METHODS

The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma

(2010) Pieter Mestdagh et al.   MOLECULAR CELL

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

TGFβ in Cancer

(2008) Joan Massagué   CELL

The significance of intrapulmonary metastasis in non-small cell lung cancer: upstaging or downstaging? A re-appraisal for the next TNM staging system☆

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