Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis

Hesperidin Protects Against Intestinal Inflammation by Restoring Intestinal Barrier Function and Up‐Regulating Treg Cells

(2019) Kun Guo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

SIRT 1/ MRPS 5 axis enhances the metabolic flexibility of liver cancer stem cells

(2019) Zhihao Wei et al.   HEPATOLOGY

Novel Pharmacological Therapy in Inflammatory Bowel Diseases: Beyond Anti-Tumor Necrosis Factor

(2019) Cristiano Pagnini et al.   Frontiers in Pharmacology

Activation of SIRT1 ameliorates LPS-induced lung injury in mice via decreasing endothelial tight junction permeability

(2018) Cuiping Fu et al.   ACTA PHARMACOLOGICA SINICA

Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK–eIF-2α–CHOP pathway in the unfolded protein response

(2018) Xiaomin Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bergenin, Acting as an Agonist of PPARγ, Ameliorates Experimental Colitis in Mice through Improving Expression of SIRT1, and Therefore Inhibiting NF-κB-Mediated Macrophage Activation

(2018) Kai Wang et al.   Frontiers in Pharmacology

Decline in Sirtuin-1 expression and activity plays a critical role in blood-brain barrier permeability in aging

(2018) Svetlana M. Stamatovic et al.   NEUROBIOLOGY OF DISEASE

Correlation of Intestinal Mucosal Healing and Tight Junction Protein Expression in Ulcerative Colitis Patients

(2018) Yue Tan et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease

(2018) Kirsty M Hooper et al.   INFLAMMATORY BOWEL DISEASES

Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota

(2017) Alicia S. Wellman et al.   GASTROENTEROLOGY

Crosstalk of ER stress-mediated autophagy and ER-phagy: Involvement of UPR and the core autophagy machinery

(2017) Shuling Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Development of an in vitro co-culture model to mimic the human intestine in healthy and diseased state

(2017) Angela A.M. Kämpfer et al.   TOXICOLOGY IN VITRO

Microbial dysbiosis in spouses of ulcerative colitis patients: Any clues to disease pathogenesis?

(2017) Dario Sorrentino   WORLD JOURNAL OF GASTROENTEROLOGY

Heat-Labile Enterotoxin-Induced PERK-CHOP Pathway Activation Causes Intestinal Epithelial Cell Apoptosis

(2017) Xi Lu et al.   Frontiers in Cellular and Infection Microbiology

Intestinal Epithelial Cell Endoplasmic Reticulum Stress and Inflammatory Bowel Disease Pathogenesis: An Update Review

(2017) Xiaoshi Ma et al.   Frontiers in Immunology

SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation

(2016) Alexandre Prola et al.   CELL DEATH AND DIFFERENTIATION

Cytokine Networks and T-Cell Subsets in Inflammatory Bowel Diseases

(2016) Mei Lan Chen et al.   INFLAMMATORY BOWEL DISEASES

Epithelial ER Stress in Crohnʼs Disease and Ulcerative Colitis

(2016) Stewart S. Cao   INFLAMMATORY BOWEL DISEASES

Sirtuins and nonalcoholic fatty liver disease

(2016) Fatiha Nassir et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Sirt1 restrains lung inflammasome activation in a murine model of sepsis

(2015) Rong Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Methyl-deficient diet promotes colitis and SIRT1-mediated endoplasmic reticulum stress

(2015) Hassan Melhem et al.   GUT

Endoplasmic Reticulum Stress and Unfolded Protein Response in Inflammatory Bowel Disease

(2015) Stewart S. Cao   INFLAMMATORY BOWEL DISEASES

SIRT1 suppresses cardiomyocyte apoptosis in diabetic cardiomyopathy: An insight into endoplasmic reticulum stress response mechanism

(2015) Rong Guo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis

(2015) Hai-Sheng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis

(2015) Genyuan Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Computational Prediction and Validation of BAHD1 as a Novel Molecule for Ulcerative Colitis

(2015) Huatuo Zhu et al.   Scientific Reports

Defective expression of SIRT1 contributes to sustain inflammatory pathways in the gut

(2014) R Caruso et al.   Mucosal Immunology

C/EBP homologous protein inhibits tissue repair in response to gut injury and is inversely regulated with chronic inflammation

(2014) N Waldschmitt et al.   Mucosal Immunology

SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1 -Dependent Glycolysis

(2013) G. Liu et al.   CANCER RESEARCH

Paneth cells as a site of origin for intestinal inflammation

(2013) Timon E. Adolph et al.   NATURE

Are sirtuins viable targets for improving healthspan and lifespan?

(2012) Joseph A. Baur et al.   NATURE REVIEWS DRUG DISCOVERY

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epidemiology and Natural History of Inflammatory Bowel Diseases

(2011) Jacques Cosnes et al.   GASTROENTEROLOGY

Altered Endoplasmic Reticulum Stress Affects Translation in Inactive Colon Tissue From Patients With Ulcerative Colitis

(2011) Xavier Tréton et al.   GASTROENTEROLOGY

Resveratrol (Trans-3,5,4'-trihydroxystilbene) Induces Silent Mating Type Information Regulation-1 and Down-Regulates Nuclear Transcription Factor- B Activation to Abrogate Dextran Sulfate Sodium-Induced Colitis

(2009) U. P. Singh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

Intestinal barrier dysfunction in inflammatory bowel diseases

(2008) Michael A. McGuckin et al.   INFLAMMATORY BOWEL DISEASES