Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

In This Issue

(2011)   CELL

Molecular Mechanism of Signal Perception and Integration by the Innate Immune Sensor Retinoic Acid-inducible Gene-I (RIG-I)

(2011) Marco Binder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reconstitution of the RIG-I Pathway Reveals a Signaling Role of Unanchored Polyubiquitin Chains in Innate Immunity

(2010) Wenwen Zeng et al.   CELL

Recognition of viruses by cytoplasmic sensors

(2010) Courtney Wilkins et al.   CURRENT OPINION IN IMMUNOLOGY

Loss-of-function mutations E6 27X and I923V of IFIH1 are associated with lower poly(I:C)–induced interferon-β production in peripheral blood mononuclear cells of type 1 diabetes patients

(2010) Dimitry A. Chistiakov et al.   HUMAN IMMUNOLOGY

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

(2010) A. Baum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIGorous Detection: Exposing Virus Through RNA Sensing

(2010) J. Rehwinkel et al.   SCIENCE

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Regulation of Signal Transduction by Enzymatically Inactive Antiviral RNA Helicase Proteins MDA5, RIG-I, and LGP2

(2009) Darja Bamming et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

(2009) Andrea Ablasser et al.   NATURE IMMUNOLOGY

Structural Plasticity in Actin and Tubulin Polymer Dynamics

(2009) H. Y. Kueh et al.   SCIENCE

Rare Variants of IFIH1, a Gene Implicated in Antiviral Responses, Protect Against Type 1 Diabetes

(2009) S. Nejentsev et al.   SCIENCE

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I

(2008) Sheng Cui et al.   MOLECULAR CELL

Mechanism of homologous recombination from the RecA–ssDNA/dsDNA structures

(2008) Zhucheng Chen et al.   NATURE

MDA-5 Recognition of a Murine Norovirus

(2008) Stephen A. McCartney et al.   PLoS Pathogens