ITGAM is a risk factor to systemic lupus erythematosus and possibly a protection factor to rheumatoid arthritis in patients from Mexico

Tumor necrosis factor gene polymorphisms are associated with systemic lupus erythematosus susceptibility or lupus nephritis in Mexican patients

(2018) Julian Ramírez-Bello et al.   IMMUNOLOGIC RESEARCH

Association of ITGAM, TNFSF4, TNFAIP3 and STAT4 gene polymorphisms with risk of systemic lupus erythematosus in a North Indian population

(2018) V Gupta et al.   LUPUS

The PTPN22 R263Q polymorphism confers protection against systemic lupus erythematosus and rheumatoid arthritis, while PTPN22 R620W confers susceptibility to Graves’ disease in a Mexican population

(2017) Daniela Josabeth López-Cano et al.   INFLAMMATION RESEARCH

Association of the CD11b rs1143679 polymorphism with systemic lupus erythematosus in the Han Chinese population

(2017) Chunmei Li et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Genetics of rheumatoid arthritis susceptibility, severity, and treatment response

(2017) Sebastien Viatte et al.   Seminars in Immunopathology

Transancestral mapping and genetic load in systemic lupus erythematosus

(2017) Carl D. Langefeld et al.   Nature Communications

Updates in Lupus Genetics

(2017) Yun Deng et al.   Current Rheumatology Reports

The functional PTPN22 C1858T polymorphism confers risk for rheumatoid arthritis in patients from Central Mexico

(2016) J. F. Mendoza Rincón et al.   CLINICAL RHEUMATOLOGY

Genetic association study of systemic lupus erythematosus and disease subphenotypes in European populations

(2016) Otsanda Ruiz-Larrañaga et al.   CLINICAL RHEUMATOLOGY

Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture

(2016) Marta E. Alarcón-Riquelme et al.   Arthritis & Rheumatology

Distribution of PTPN22 polymorphisms in SLE from western Mexico: correlation with mRNA expression and disease activity

(2015) Jesús René Machado-Contreras et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Combined protein- and nucleic acid-level effects of rs1143679 (R77H), a lupus-predisposing variant within ITGAM

(2014) A. K. Maiti et al.   HUMAN MOLECULAR GENETICS

Resequencing the susceptibility gene, ITGAM, identifies two functionally deleterious rare variants in systemic lupus erythematosus cases

(2014) Amy L Roberts et al.   ARTHRITIS RESEARCH & THERAPY

Thers1143679(R77H) lupus associated variant ofITGAM(CD11b) impairs complement receptor 3 mediated functions in human monocytes

(2012) Benjamin Rhodes et al.   ANNALS OF THE RHEUMATIC DISEASES

Admixture and population structure in Mexican-Mestizos based on paternal lineages

(2012) Gabriela Martínez-Cortés et al.   JOURNAL OF HUMAN GENETICS

Replication of recently identified systemic lupus erythematosus genetic associations: a case–control study

(2012) Marian Suarez-Gestal et al.   ARTHRITIS RESEARCH & THERAPY

Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study

(2011) Elena Sánchez et al.   ARTHRITIS AND RHEUMATISM

Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases

(2011) Juan-Manuel Anaya et al.   AUTOIMMUNITY REVIEWS

Evaluation of 19 Autoimmune Disease-associated Loci with Rheumatoid Arthritis in a Colombian Population: Evidence for Replication and Gene-Gene Interaction

(2011) H. A. DESHMUKH et al.   JOURNAL OF RHEUMATOLOGY

A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap

(2011) Paula S. Ramos et al.   PLoS Genetics

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus

(2010) G. Orozco et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus

(2010) Elena Sanchez et al.   ARTHRITIS AND RHEUMATISM

Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors

(2009) Marian Suarez-Gestal et al.   ARTHRITIS AND RHEUMATISM

Admixture in Hispanic Americans: its impact on ITGAM association and implications for admixture mapping in SLE

(2009) J E Molineros et al.   GENES AND IMMUNITY

Tumor necrosis factor–α is a common genetic risk factor for asthma, juvenile rheumatoid arthritis, and systemic lupus erythematosus in a Mexican pediatric population

(2009) Silvia Jiménez-Morales et al.   HUMAN IMMUNOLOGY

ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai

(2009) Wanling Yang et al.   HUMAN MOLECULAR GENETICS

Evaluation of imputation-based association in and around the integrin- -M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE)

(2009) S. Han et al.   HUMAN MOLECULAR GENETICS

REL, encoding a member of the NF-κB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis

(2009) Peter K Gregersen et al.   NATURE GENETICS

No evidence for association of the systemic lupus erythematosus-associated ITGAM variant, R77H, with rheumatoid arthritis in the Caucasian population

(2009) A. J. Phipps-Green et al.   RHEUMATOLOGY

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

(2008) Swapan K Nath et al.   NATURE GENETICS

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS

Association of Systemic Lupus Erythematosus withC8orf13–BLKandITGAM–ITGAX

(2008) Geoffrey Hom et al.   NEW ENGLAND JOURNAL OF MEDICINE