Gene of the issue: ANO6 and Scott Syndrome

Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F

(2019) Carolina Alvadia et al.   eLife

TMEM16F inhibition limits pain-associated behavior and improves motor function by promoting microglia M2 polarization in mice

(2019) Jing Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Unknown

(2018)   BRITISH JOURNAL OF HAEMATOLOGY

OUP accepted manuscript

(2018)   JOURNAL OF INFECTIOUS DISEASES

TMEM16F-Mediated Platelet Membrane Phospholipid Scrambling Is Critical for Hemostasis and Thrombosis but not Thromboinflammation in Mice—Brief ReportHighlights

(2016) Ayesha A. Baig et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage

(2016) Nadine J. A. Mattheij et al.   FASEB JOURNAL

Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion

(2016) Yu Hu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Combined Quantification of the Global Proteome, Phosphoproteome, and Proteolytic Cleavage to Characterize Altered Platelet Functions in the Human Scott Syndrome

(2016) Fiorella A. Solari et al.   MOLECULAR & CELLULAR PROTEOMICS

Unknown

(2015)   BRITISH JOURNAL OF HAEMATOLOGY

Coordinated Membrane Ballooning and Procoagulant Spreading in Human PlateletsClinical Perspective

(2015) Ejaife O. Agbani et al.   CIRCULATION

Anoctamin-6 Controls Bone Mineralization by Activating the Calcium Transporter NCX1

(2015) Jiraporn Ousingsawat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATMEM16Fpoint mutation causes an absence of canine platelet TMEM16F and ineffective activation and death-induced phospholipid scrambling

(2015) M. B. Brooks et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets

(2015) Toshihiro Fujii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation

(2012) Huanghe Yang et al.   CELL

Platelet-based coagulation: different populations, different functions

(2012) J. W. M. HEEMSKERK et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Compound heterozygosity for 2 novel TMEM16F mutations in a patient with Scott syndrome

(2011) E. Castoldi et al.   BLOOD

Diagnosis of Scott syndrome in patient with bleeding disorder of unknown cause

(2011) Mariane C. Flores-Nascimento et al.   BLOOD COAGULATION & FIBRINOLYSIS

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Absence of platelet-dependent fibrin formation in a patient with Scott syndrome

(2009) Simone J. H. Wielders et al.   THROMBOSIS AND HAEMOSTASIS