Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions

Discovery of Small-Molecule Antibiotics against a Unique tRNA-Mediated Regulation of Transcription in Gram-Positive Bacteria

(2019) Kyla M. Frohlich et al.   ChemMedChem

An evolving tale of two interacting RNAs-themes and variations of the T-box riboswitch mechanism

(2019) Krishna C. Suddala et al.   IUBMB LIFE

New tRNA contacts facilitate ligand binding in aMycobacterium smegmatisT box riboswitch

(2018) Anna V. Sherwood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mRNA structure determines specificity of a polyQ-driven phase separation

(2018) Erin M. Langdon et al.   SCIENCE

Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach

(2018) Kaiming Zhang et al.   STRUCTURE

Hierarchical mechanism of amino acid sensing by the T-box riboswitch

(2018) Krishna C. Suddala et al.   Nature Communications

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

Emerging Roles for Intermolecular RNA-RNA Interactions in RNP Assemblies

(2018) Briana Van Treeck et al.   CELL

ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands

(2018) Alla Peselis et al.   Nature Chemical Biology

Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand

(2018) Jiacheng Zhang et al.   eLife

Pervasive tertiary structure in the dengue virus RNA genome

(2018) Elizabeth A. Dethoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ensemble cryo-EM elucidates the mechanism of translation fidelity

(2017) Anna B. Loveland et al.   NATURE

Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography

(2017) J. R. Stagno et al.   NATURE

RNA phase transitions in repeat expansion disorders

(2017) Ankur Jain et al.   NATURE

Convolutional neural networks for automated annotation of cellular cryo-electron tomograms

(2017) Muyuan Chen et al.   NATURE METHODS

Molecular envelope and atomic model of an anti-terminated glyQS T-box regulator in complex with tRNAGly

(2017) Bhaskar Chetnani et al.   NUCLEIC ACIDS RESEARCH

Direct modulation of T-box riboswitch-controlled transcription by protein synthesis inhibitors

(2017) Vassiliki Stamatopoulou et al.   NUCLEIC ACIDS RESEARCH

Rfam 13.0: shifting to a genome-centric resource for non-coding RNA families

(2017) Ioanna Kalvari et al.   NUCLEIC ACIDS RESEARCH

ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

(2017) D. Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

(2016) Lynne Chantranupong et al.   CELL

Ribosome-dependent activation of stringent control

(2016) Alan Brown et al.   NATURE

Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria

(2016) D. Dar et al.   SCIENCE

Ribosome•RelA structures reveal the mechanism of stringent response activation

(2016) Anna B Loveland et al.   eLife

Factors that influence T box riboswitch efficacy and tRNA affinity

(2015) C. Zeng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Nutrient-Sensing Mechanisms across Evolution

(2015) Lynne Chantranupong et al.   CELL

Identification of Spermidine Binding Site in T-box Riboswitch Antiterminator RNA

(2015) Jia Liu et al.   Chemical Biology & Drug Design

SEDPHAT – A platform for global ITC analysis and global multi-method analysis of molecular interactions

(2015) Huaying Zhao et al.   METHODS

T box riboswitches in Actinobacteria: Translational regulation via novel tRNA interactions

(2015) Anna V. Sherwood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AglyST-box riboswitch with species-specific structural features responding to both proteinogenic and nonproteinogenic tRNAGlyisoacceptors

(2015) Maria Apostolidi et al.   RNA

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

(2015) R. A. Saxton et al.   SCIENCE

Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch

(2015) Aiming Ren et al.   Cell Reports

Structure and mechanism of the T-box riboswitches

(2015) Jinwei Zhang et al.   Wiley Interdisciplinary Reviews-RNA

Direct Evaluation of tRNA Aminoacylation Status by the T-Box Riboswitch Using tRNA-mRNA Stacking and Steric Readout

(2014) Jinwei Zhang et al.   MOLECULAR CELL

The importance of helix P1 stability for structural pre-organization and ligand binding affinity of the adenine riboswitch aptamer domain

(2014) Senada Nozinovic et al.   RNA Biology

tRNA synthetase: tRNA aminoacylation and beyond

(2014) Yan Ling Joy Pang et al.   Wiley Interdisciplinary Reviews-RNA

Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography

(2013) James Foadi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

An Unusual Topological Structure of the HIV-1 Rev Response Element

(2013) Xianyang Fang et al.   CELL

Co-crystal structure of a T-box riboswitch stem I domain in complex with its cognate tRNA

(2013) Jinwei Zhang et al.   NATURE

A universal RNA structural motif docking the elbow of tRNA in the ribosome, RNAse P and T-box leaders

(2013) Jean Lehmann et al.   NUCLEIC ACIDS RESEARCH

Two-codon T-box riboswitch binding two tRNAs

(2013) N. Y. Saad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T box RNA decodes both the information content and geometry of tRNA to affect gene expression

(2013) J. C. Grigg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Determinants for Geometry and Information Decoding of tRNA by T Box Leader RNA

(2013) Jason C. Grigg et al.   STRUCTURE

High-Precision Isothermal Titration Calorimetry with Automated Peak-Shape Analysis

(2012) Sandro Keller et al.   ANALYTICAL CHEMISTRY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Correcting pervasive errors in RNA crystallography through enumerative structure prediction

(2012) Fang-Chieh Chou et al.   NATURE METHODS

ViennaRNA Package 2.0

(2011) Ronny Lorenz et al.   Algorithms for Molecular Biology

Prevalence of syn nucleobases in the active sites of functional RNAs

(2011) J. E. Sokoloski et al.   RNA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Structural and Functional Diversity of Metabolite-Binding Riboswitches

(2009) Adam Roth et al.   Annual Review of Biochemistry

Amino acid recognition and gene regulation by riboswitches

(2009) Alexander Serganov et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A Method for Helical RNA Global Structure Determination in Solution Using Small-Angle X-Ray Scattering and NMR Measurements

(2009) Jinbu Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Biochemical Features and Functional Implications of the RNA-Based T-Box Regulatory Mechanism

(2009) A. Gutierrez-Preciado et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme

(2008) Hong Xiao et al.   NATURE

Comparative genomic analysis of T-box regulatory systems in bacteria

(2008) A. G. Vitreschak et al.   RNA