Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

(2018) Mats Nagel et al.   NATURE GENETICS

Insomnia—perchance a dream? Results from a NREM/REM sleep awakening study in good sleepers and patients with insomnia

(2018) Bernd Feige et al.   SLEEP

Causal associations between risk factors and common diseases inferred from GWAS summary data

(2018) Zhihong Zhu et al.   Nature Communications

Sleep Dysfunction and EEG Alterations in Mice Overexpressing Alpha-Synuclein

(2018) Kimberly A. McDowell et al.   Journal of Parkinsons Disease

Insomnia—perchance a dream? Results from a NREM/REM sleep awakening study in good sleepers and patients with insomnia

(2018) Bernd Feige et al.   SLEEP

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis

(2017) Barbara Schormair et al.   LANCET NEUROLOGY

Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits

(2017) Anke R Hammerschlag et al.   NATURE GENETICS

Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence

(2017) Suzanne Sniekers et al.   NATURE GENETICS

SNCA 3′UTR genetic variants in patients with Parkinson’s disease and REM sleep behavior disorder

(2017) M. Toffoli et al.   NEUROLOGICAL SCIENCES

Insomnia heterogeneity: Characteristics to consider for data-driven multivariate subtyping

(2017) Jeroen S. Benjamins et al.   SLEEP MEDICINE REVIEWS

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Insomnia with objective short sleep duration is associated with longer duration of insomnia in the Freiburg Insomnia Cohort compared to insomnia with normal sleep duration, but not with hypertension

(2017) Anna F. Johann et al.   PLoS One

Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits

(2016) Jacqueline M Lane et al.   NATURE GENETICS

Identification of context-dependent expression quantitative trait loci in whole blood

(2016) Daria V Zhernakova et al.   NATURE GENETICS

The statistical properties of gene-set analysis

(2016) Christiaan A. de Leeuw et al.   NATURE REVIEWS GENETICS

Mapping inflammation onto mood: Inflammatory mediators of anhedonia

(2016) Walter Swardfager et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

(2016) Jacqueline MacArthur et al.   NUCLEIC ACIDS RESEARCH

Slow dissolving of emotional distress contributes to hyperarousal

(2016) Rick Wassing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wake High-Density Electroencephalographic Spatiospectral Signatures of Insomnia

(2016) Michele A. Colombo et al.   SLEEP

I Keep a Close Watch on This Heart of Mine: Increased Interoception in Insomnia

(2016) Yishul Wei et al.   SLEEP

GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person

(2016) Youna Hu et al.   Nature Communications

Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank

(2016) Jacqueline M. Lane et al.   Nature Communications

A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome

(2016) Anthony D. Schmitt et al.   Cell Reports

Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci

(2016) Samuel E. Jones et al.   PLoS Genetics

Wake High-Density Electroencephalographic Spatiospectral Signatures of Insomnia

(2016) Michele A. Colombo et al.   SLEEP

I Keep a Close Watch on This Heart of Mine: Increased Interoception in Insomnia

(2016) Yishul Wei et al.   SLEEP

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

High-Resolution Chromosome Ideogram Representation of Currently Recognized Genes for Autism Spectrum Disorders

(2015) Merlin Butler et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Canonical genetic signatures of the adult human brain

(2015) Michael Hawrylycz et al.   NATURE NEUROSCIENCE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

A Longitudinal Twin Study of Insomnia Symptoms in Adults

(2015) Mackenzie J. Lind et al.   SLEEP

Genetic variants associated with sleep disorders

(2015) Daniel F. Kripke et al.   SLEEP MEDICINE

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Insomnia disorder

(2015) Charles M. Morin et al.   Nature Reviews Disease Primers

The supramammillary nucleus and the claustrum activate the cortex during REM sleep

(2015) L. Renouard et al.   Science Advances

A Longitudinal Twin Study of Insomnia Symptoms in Adults

(2015) Mackenzie J. Lind et al.   SLEEP

PRSice: Polygenic Risk Score software

(2014) Jack Euesden et al.   BIOINFORMATICS

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

The caudate: a key node in the neuronal network imbalance of insomnia?

(2013) Diederick Stoffers et al.   BRAIN

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Behavioral and biochemical dissociation of arousal and homeostatic sleep need influenced by prior wakeful experience in mice

(2013) A. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sleep Fragmentation and Motor Restlessness in a Drosophila Model of Restless Legs Syndrome

(2012) Amanda Freeman et al.   CURRENT BIOLOGY

Motor restlessness, sleep disturbances, thermal sensory alterations and elevated serum iron levels in Btbd9 mutant mice

(2012) Mark P. DeAndrade et al.   HUMAN MOLECULAR GENETICS

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

Enhanced Hippocampal Long-Term Potentiation and Fear Memory in Btbd9 Mutant Mice

(2012) Mark P. DeAndrade et al.   PLoS One

How do the basal ganglia regulate sleep–wake behavior?

(2012) Michael Lazarus et al.   TRENDS IN NEUROSCIENCES

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

The size and burden of mental disorders and other disorders of the brain in Europe 2010

(2011) H.U. Wittchen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Efficient Replication of over 180 Genetic Associations with Self-Reported Medical Data

(2011) Joyce Y. Tung et al.   PLoS One

Genome-Wide Association Study Confirms SNPs inSNCAand theMAPTRegion as Common Risk Factors for Parkinson Disease

(2010) Todd L. Edwards et al.   ANNALS OF HUMAN GENETICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Insomnia and its correlates in a representative sample of the Greek population

(2010) Thomas Paparrigopoulos et al.   BMC PUBLIC HEALTH

Basal ganglia control of sleep-wake behavior and cortical activation

(2010) Mei-Hong Qiu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Role of Basal Ganglia in Sleep–Wake Regulation: Neural Circuitry and Clinical Significance

(2010) Ramalingam Vetrivelan et al.   Frontiers in Neuroanatomy

Web-Based, Participant-Driven Studies Yield Novel Genetic Associations for Common Traits

(2010) Nicholas Eriksson et al.   PLoS Genetics

Epidemiology of Insomnia in Korean Adults: Prevalence and Associated Factors

(2009) Yong Won Cho et al.   Journal of Clinical Neurology

Polymorphisms near EXOC4 and LRGUK on chromosome 7q32 are associated with Type 2 Diabetes and fasting glucose; The NHLBI Family Heart Study

(2008) Jason M Laramie et al.   BMC Medical Genetics