Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks

Mammalian Circadian Period, But Not Phase and Amplitude, Is Robust Against Redox and Metabolic Perturbations

(2018) Marrit Putker et al.   ANTIOXIDANTS & REDOX SIGNALING

NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus

(2018) Ryan S Wible et al.   eLife

Diverse Redoxome Reactivity Profiles of Carbon Nucleophiles

(2017) Vinayak Gupta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Systematic and Quantitative Assessment of Hydrogen Peroxide Reactivity With Cysteines Across Human Proteomes

(2017) Ling Fu et al.   MOLECULAR & CELLULAR PROTEOMICS

Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis

(2016) Selma Masri et al.   CELL

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation

(2016) Xuan Zhao et al.   CELL

Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations

(2016) Christoph A. Thaiss et al.   CELL

Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic AneurysmNovelty and Significance

(2016) Hou-Zao Chen et al.   CIRCULATION RESEARCH

Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT)

(2016) Mi Lai et al.   MOLECULAR & CELLULAR PROTEOMICS

Transcriptional architecture of the mammalian circadian clock

(2016) Joseph S. Takahashi   NATURE REVIEWS GENETICS

Circadian time signatures of fitness and disease

(2016) Joseph Bass et al.   SCIENCE

NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators

(2016) Dominic Landgraf et al.   PLoS Genetics

The Redox Code

(2015) Dean P. Jones et al.   ANTIOXIDANTS & REDOX SIGNALING

p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans

(2015) Stefano Ciciliot et al.   DIABETOLOGIA

Sox2 Deacetylation by Sirt1 Is Involved in Mouse Somatic Reprogramming

(2015) Wen-Li Mu et al.   STEM CELLS

Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations

(2015) Lv-Zhen Huang et al.   Nature Communications

Metabolic and Nontranscriptional Circadian Clocks: Eukaryotes

(2014) Akhilesh B. Reddy et al.   Annual Review of Biochemistry

Partitioning Circadian Transcription by SIRT6 Leads to Segregated Control of Cellular Metabolism

(2014) Selma Masri et al.   CELL

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

(2014) C. Esnault et al.   GENES & DEVELOPMENT

Proteomic analysis of peptides tagged with dimedone and related probes

(2014) Pablo Martínez-Acedo et al.   JOURNAL OF MASS SPECTROMETRY

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

(2014) Bin Shen et al.   NATURE METHODS

Cellular mechanisms and physiological consequences of redox-dependent signalling

(2014) Kira M. Holmström et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selective inhibition of protein kinase C β2 attenuates the adaptor P66Shc-mediated intestinal ischemia–reperfusion injury

(2014) Z Chen et al.   Cell Death & Disease

Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide

(2014) Yulia G. Ermakova et al.   Nature Communications

Disturbances in the murine hepatic circadian clock in alcohol-induced hepatic steatosis

(2014) Peng Zhou et al.   Scientific Reports

Sulfenic acid chemistry, detection and cellular lifetime

(2013) Vinayak Gupta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Reprogramming of the Circadian Clock by Nutritional Challenge

(2013) Kristin L. Eckel-Mahan et al.   CELL

SIRT1 Mediates Central Circadian Control in the SCN by a Mechanism that Decays with Aging

(2013) Hung-Chun Chang et al.   CELL

Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery

(2013) Candice E. Paulsen et al.   CHEMICAL REVIEWS

Proteome-wide profiling of activated transcription factors with a concatenated tandem array of transcription factor response elements

(2013) C. Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective upregulation of p66-Shc gene expression in the liver and brain of aged rats

(2012) Kiyoaki Sone et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

Peroxiredoxins are conserved markers of circadian rhythms

(2012) Rachel S. Edgar et al.   NATURE

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

(2012) N. Huang et al.   SCIENCE

Repression of P66Shc Expression by SIRT1 Contributes to the Prevention of Hyperglycemia-Induced Endothelial Dysfunction

(2011) Shuang Zhou et al.   CIRCULATION RESEARCH

Circadian clocks in human red blood cells

(2011) John S. O’Neill et al.   NATURE

Circadian rhythms: Redox redux

(2011) Joseph Bass et al.   NATURE

Poly(ADP-Ribose) Polymerase 1 Participates in the Phase Entrainment of Circadian Clocks to Feeding

(2010) Gad Asher et al.   CELL

Methods for detection and measurement of hydrogen peroxide inside and outside of cells

(2010) Sue Goo Rhee et al.   MOLECULES AND CELLS

Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance

(2010) S. C. Ranieri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology