NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus

Mammalian Circadian Period, But Not Phase and Amplitude, Is Robust Against Redox and Metabolic Perturbations

(2018) Marrit Putker et al.   ANTIOXIDANTS & REDOX SIGNALING

Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo

(2018) Ryan S. Wible et al.   MOLECULAR PHARMACOLOGY

Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity

(2017) Anna Kriebs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

(2017) Helmut Sies   Redox Biology

The Pentose Phosphate Pathway Regulates the Circadian Clock

(2016) Guillaume Rey et al.   Cell Metabolism

Reciprocal Control of the Circadian Clock and Cellular Redox State - a Critical Appraisal

(2016)   MOLECULES AND CELLS

Transcriptional architecture of the mammalian circadian clock

(2016) Joseph S. Takahashi   NATURE REVIEWS GENETICS

Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes

(2016) Elizabeth A. Yu et al.   Aging-US

Hepatic Bmal1 Regulates Rhythmic Mitochondrial Dynamics and Promotes Metabolic Fitness

(2015) David Jacobi et al.   Cell Metabolism

Molecular basis of the Keap1–Nrf2 system

(2015) Takafumi Suzuki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox rhythm reinforces the circadian clock to gate immune response

(2015) Mian Zhou et al.   NATURE

Nonfunctional intra- and suprasellar tumor in a patient with visual disturbance and panhypopituitarism

(2015) Rie Saito et al.   NEUROPATHOLOGY

JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

(2015) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

Pancreatic   cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

(2015) M. Perelis et al.   SCIENCE

Discrete functions of nuclear receptor Rev-erb  couple metabolism to the clock

(2015) Y. Zhang et al.   SCIENCE

Circadian redox oscillations and metabolism

(2015) Nikolay B. Milev et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis

(2014) V. Pekovic-Vaughan et al.   GENES & DEVELOPMENT

Role of Metabolic H2O2Generation

(2014) Helmut Sies   JOURNAL OF BIOLOGICAL CHEMISTRY

A circadian gene expression atlas in mammals: Implications for biology and medicine

(2014) Ray Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Machine Learning Helps Identify CHRONO as a Circadian Clock Component

(2014) Ron C. Anafi et al.   PLOS BIOLOGY

Cell Type-Specific Functions of Period Genes Revealed by Novel Adipocyte and Hepatocyte Circadian Clock Models

(2014) Chidambaram Ramanathan et al.   PLoS Genetics

Oxidative Stress and Inflammation Modulate Rev-erbα Signaling in the Neonatal Lung and Affect Circadian Rhythmicity

(2013) Guang Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of Circadian Clocks by Redox Homeostasis

(2013) Alessandra Stangherlin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bmal1 and  -Cell Clock Are Required for Adaptation to Circadian Disruption, and Their Loss of Function Leads to Oxidative Stress-Induced  -Cell Failure in Mice

(2013) J. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice

(2013) C. B. Peek et al.   SCIENCE

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

Circadian topology of metabolism

(2012) Joseph Bass   NATURE

Peroxiredoxins are conserved markers of circadian rhythms

(2012) Rachel S. Edgar et al.   NATURE

Diurnal Variation of Hepatic Antioxidant Gene Expression in Mice

(2012) Yi-Qiao Xu et al.   PLoS One

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters

(2012) Chidambaram Ramanathan et al.   Jove-Journal of Visualized Experiments

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation

(2010) Barry R. Imhoff et al.   CELL BIOLOGY AND TOXICOLOGY

Clocks not winding down: unravelling circadian networks

(2010) Eric E. Zhang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice

(2009) Melinda S. Yates et al.   CARCINOGENESIS

EGF receptor signaling blocks aryl hydrocarbon receptor-mediated transcription and cell differentiation in human epidermal keratinocytes

(2009) C. H. Sutter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Network Features of the Mammalian Circadian Clock

(2009) Julie E Baggs et al.   PLOS BIOLOGY

Circadian Expression Profiles of Drug-Processing Genes and Transcription Factors in Mouse Liver

(2008) Y.-K. J. Zhang et al.   DRUG METABOLISM AND DISPOSITION

Searching for Genes Underlying Behavior: Lessons from Circadian Rhythms

(2008) J. S. Takahashi et al.   SCIENCE

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

(2008) Andrew C. Liu et al.   PLoS Genetics