p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans

The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells

(2015) Annalisa Natalicchio et al.   DIABETOLOGIA

Diabetes Causes Bone Marrow Autonomic Neuropathy and Impairs Stem Cell Mobilization via Dysregulated p66Shc and Sirt1

(2013) M. Albiero et al.   DIABETES

The influence of acute, late-life calorie restriction on whole body energy metabolism in p66Shc(−/−) mice

(2012) Jennifer H. Stern et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Influence of Shc Proteins and Aging on Whole Body Energy Expenditure and Substrate Utilization in Mice

(2012) Jennifer H. Stern et al.   PLoS One

Quantitative dynamics of adipose cells

(2012) Junghyo Jo et al.   Adipocyte

The p66Shcknockout mice are short lived under natural condition

(2011) Marco Giorgio et al.   AGING CELL

Adipose Tissue Extracellular Matrix and Vascular Abnormalities in Obesity and Insulin Resistance

(2011) Michael Spencer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

The Shc locus regulates insulin signaling and adiposity in mammals

(2010) Alexey A. Tomilov et al.   AGING CELL

The Redox Enzyme p66Shc Contributes to Diabetes and Ischemia-Induced Delay in Cutaneous Wound Healing

(2010) G. P. Fadini et al.   DIABETES

Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance

(2010) S. C. Ranieri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood orange juice inhibits fat accumulation in mice

(2009) L Titta et al.   INTERNATIONAL JOURNAL OF OBESITY

p66Shc-generated Oxidative Signal Promotes Fat Accumulation

(2008) Ina Berniakovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY