A dynamical systems model for the measurement of cellular senescence

Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2

(2018) Eva Latorre et al.   Aging-US

Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence

(2018) Guillaume Collin et al.   Cell Death & Disease

FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence

(2018) Eva Latorre et al.   FASEB JOURNAL

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

(2018) Tyler J. Bussian et al.   NATURE

Comparison of several commonly used detection indicators of cell senescence

(2018) Yuanyuan Xiao et al.   DRUG AND CHEMICAL TOXICOLOGY

Systems modelling ageing: from single senescent cells to simple multi-cellular models

(2017) Alvaro Martinez Guimera et al.   Essays in Biochemistry

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

(2017) Ok Hee Jeon et al.   NATURE MEDICINE

Senescent cells: an emerging target for diseases of ageing

(2017) Bennett G. Childs et al.   NATURE REVIEWS DRUG DISCOVERY

Cellular senescence drives age-dependent hepatic steatosis

(2017) Mikolaj Ogrodnik et al.   Nature Communications

Biomarkers to identify and isolate senescent cells

(2016) Mantas Matjusaitis et al.   AGEING RESEARCH REVIEWS

Small molecule compounds that induce cellular senescence

(2016) Nadezhda V. Petrova et al.   AGING CELL

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice

(2016) Carolyn M. Roos et al.   AGING CELL

The cell fate: senescence or quiescence

(2016) Menderes Yusuf Terzi et al.   MOLECULAR BIOLOGY REPORTS

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

Cellular senescence in renal ageing and disease

(2016) Ines Sturmlechner et al.   Nature Reviews Nephrology

Modeling of replicative senescence in hematopoietic development

(2016) Anna Marciniak-Czochra et al.   Aging-US

Cell cycle arrest is not senescence

(2016) Mikhail V. Blagosklonny   Aging-US

Senescence from G2 arrest, revisited

(2015) Véronique Gire et al.   CELL CYCLE

Quantifying replicative senescence as a tumor suppressor pathway and a target for cancer therapy

(2015) Ignacio A. Rodriguez-Brenes et al.   Scientific Reports

Targeting senescent cells enhances adipogenesis and metabolic function in old age

(2015) Ming Xu et al.   eLife

Cancer-Associated Mutations in Healthy Individuals: Assessing the Risk of Carcinogenesis

(2014) Ignacio A. Rodriguez-Brenes et al.   CANCER RESEARCH

The hallmarks of fibroblast ageing

(2014) Julia Tigges et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

(2014) Piero Dalle Pezze et al.   PLoS Computational Biology

Changes in splicing factor expression are associated with advancing age in man

(2013) Alice C. Holly et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Senescence and aging: the critical roles of p53

(2013) A Rufini et al.   ONCOGENE

A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations

(2012) Conor Lawless et al.   PLoS One

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Quantitative assessment of markers for cell senescence

(2010) Conor Lawless et al.   EXPERIMENTAL GERONTOLOGY

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Paradoxical Dependencies of Tumor Dormancy and Progression on Basic Cell Kinetics

(2009) H. Enderling et al.   CANCER RESEARCH