Human Immunodeficiency Virus-1 Viral Load Is Elevated in Individuals With Reverse-Transcriptase Mutation M184V/I During Virological Failure of First-Line Antiretroviral Therapy and Is Associated With Compensatory Mutation L74I

Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa

(2017) Ruth L. Goodall et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Rates of virological suppression and drug resistance in adult HIV-1-positive patients attending primary healthcare facilities in KwaZulu-Natal, South Africa

(2017) Gillian M Hunt et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Occult HIV-1 drug resistance to thymidine analogues following failure of first-line tenofovir combined with a cytosine analogue and nevirapine or efavirenz in sub Saharan Africa: a retrospective multi-centre cohort study

(2017) John Gregson et al.   LANCET INFECTIOUS DISEASES

Boosted protease inhibitor monotherapy versus boosted protease inhibitor plus lamivudine dual therapy as second-line maintenance treatment for HIV-1-infected patients in sub-Saharan Africa (ANRS12 286/MOBIDIP): a multicentre, randomised, parallel, open-label, superiority trial

(2017) Laura Ciaffi et al.   Lancet HIV

Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration

(2017) Soo-Yon Rhee et al.   EBioMedicine

Mutational Heterogeneity in p6 Gag Late Assembly (L) Domains in HIV-1 Subtype C Viruses from South Africa

(2016) Ujjwal Neogi et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Genotypic HIV-1 Drug Resistance Among Patients Failing Tenofovir-Based First-Line HAART in South India

(2016) Thongadi Ramesh Dinesha et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Antiretroviral Resistance After First-Line Antiretroviral Therapy Failure in Diverse HIV-1 Subtypes in the SECOND-LINE Study

(2016) Edward P. Lam et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV-1 antiretroviral drug resistance patterns in patients failing NNRTI-based treatment: results from a national survey in South Africa

(2016) K. Steegen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa

(2016) T. Sonia Boender et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study

(2016) John Gregson et al.   LANCET INFECTIOUS DISEASES

Lamivudine Monotherapy

(2016) Verena Linder et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Drug resistance mutations after the first 12 months on antiretroviral therapy and determinants of virological failure in Rwanda

(2016) Jean d'Amour Ndahimana et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Treatment failure and drug resistance in HIV-positive patients on tenofovir-based first-line antiretroviral therapy in western Kenya

(2016) Katherine Brooks et al.   Journal of the International AIDS Society

High Prevalence of the K65R Mutation in HIV-1 Subtype C Infected Patients Failing Tenofovir-Based First-Line Regimens in South Africa

(2015) Lindiwe Skhosana et al.   PLoS One

Virological Response and Antiretroviral Drug Resistance Emerging during Antiretroviral Therapy at Three Treatment Centers in Uganda

(2015) Pontiano Kaleebu et al.   PLoS One

Increased Virological Failure in Naive HIV-1-Infected Patients Taking Lamivudine Compared With Emtricitabine in Combination With Tenofovir and Efavirenz or Nevirapine in the Dutch Nationwide ATHENA Cohort

(2014) C. Rokx et al.   CLINICAL INFECTIOUS DISEASES

Temporal Trends in the Swedish HIV-1 Epidemic: Increase in Non-B Subtypes and Recombinant Forms over Three Decades

(2014) Ujjwal Neogi et al.   PLoS One

HIV multi-drug resistance at first-line antiretroviral failure and subsequent virological response in Asia

(2014) Awachana Jiamsakul et al.   Journal of the International AIDS Society

Resistance to tenofovir-based regimens during treatment failure of subtype C HIV-1 in South Africa

(2013) Christopher J Hoffmann et al.   ANTIVIRAL THERAPY

Trends in Genotypic HIV-1 Antiretroviral Resistance between 2006 and 2012 in South African Patients Receiving First- and Second-Line Antiretroviral Treatment Regimens

(2013) Gert U. Van Zyl et al.   PLoS One

High rate of K65R for antiretroviral therapy-naive patients with subtype C HIV infection failing a tenofovir-containing first-line regimen

(2012) Henry Sunpath et al.   AIDS

Tenofovir-based regimens associated with less drug resistance in HIV-1-infected Nigerians failing first-line antiretroviral therapy

(2012) Mary-Ann A. Etiebet et al.   AIDS

HIV-1 Subtype Is an Independent Predictor of Reverse Transcriptase Mutation K65R in HIV-1 Patients Treated with Combination Antiretroviral Therapy Including Tenofovir

(2012) K. Theys et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Virological Response and HIV Drug Resistance 12 Months After Antiretroviral Therapy Initiation at 2 Clinics in Nigeria

(2012) R. Ugbena et al.   CLINICAL INFECTIOUS DISEASES

HIV-1 Amino Acid Changes Among Participants With Virologic Failure: Associations With First-line Efavirenz or Atazanavir Plus Ritonavir and Disease Status

(2012) K. Mollan et al.   JOURNAL OF INFECTIOUS DISEASES

La cohorte de la red española de investigación en sida y su biobanco: organización, principales resultados y pérdidas al seguimiento

(2011) Paz Sobrino-Vegas et al.   ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

Unnecessary Antiretroviral Treatment Switches and Accumulation of HIV Resistance Mutations; Two Arguments for Viral Load Monitoring in Africa

(2011) Kim C E Sigaloff et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

A Leu to Ile but not Leu to Val change at HIV-1 reverse transcriptase codon 74 in the background of K65R mutation leads to an increased processivity of K65R+L74I enzyme and a replication competent virus

(2011) HimaBindu Chunduri et al.   Virology Journal

Full-length HIV-1 Gag determines protease inhibitor susceptibility within in-vitro assays

(2010) Ravindra K Gupta et al.   AIDS

Virological monitoring and resistance to first-line highly active antiretroviral therapy in adults infected with HIV-1 treated under WHO guidelines: a systematic review and meta-analysis

(2009) Ravindra K Gupta et al.   LANCET INFECTIOUS DISEASES

Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration

(2009) R. K. Gupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiretroviral combinations implicated in emergence of the L74I and L74V resistance mutations in HIV-1-infected patients

(2008) Marc Wirden et al.   AIDS

In Vivo Fitness Cost of the M184V Mutation in Multidrug-Resistant Human Immunodeficiency Virus Type 1 in the Absence of Lamivudine

(2008) R. Paredes et al.   JOURNAL OF VIROLOGY

Class-Sparing Regimens for Initial Treatment of HIV-1 Infection

(2008) Sharon A. Riddler et al.   NEW ENGLAND JOURNAL OF MEDICINE