Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa

Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study

(2016) John Gregson et al.   LANCET INFECTIOUS DISEASES

Treatment failure and drug resistance in HIV-positive patients on tenofovir-based first-line antiretroviral therapy in western Kenya

(2016) Katherine Brooks et al.   Journal of the International AIDS Society

Safety of zidovudine dose reduction in treatment-naïve HIV infected patients. A randomized controlled study (MiniZID)

(2015) M Rougemont et al.   HIV MEDICINE

Virological Response and Antiretroviral Drug Resistance Emerging during Antiretroviral Therapy at Three Treatment Centers in Uganda

(2015) Pontiano Kaleebu et al.   PLoS One

Assessment of Second-Line Antiretroviral Regimens for HIV Therapy in Africa

(2014) Nicholas I. Paton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resistance at Virological Failure Using Boosted Protease Inhibitors Versus Nonnucleoside Reverse Transcriptase Inhibitors As First-Line Antiretroviral Therapy—Implications for Sustained Efficacy of ART in Resource-Limited Settings

(2013) Andrew Hill et al.   JOURNAL OF INFECTIOUS DISEASES

Emergence of HIV Drug Resistance During First- and Second-Line Antiretroviral Therapy in Resource-Limited Settings

(2013) Mina C. Hosseinipour et al.   JOURNAL OF INFECTIOUS DISEASES

High Coverage of ART Associated with Decline in Risk of HIV Acquisition in Rural KwaZulu-Natal, South Africa

(2013) F. Tanser et al.   SCIENCE

Increases in Adult Life Expectancy in Rural South Africa: Valuing the Scale-Up of HIV Treatment

(2013) J. Bor et al.   SCIENCE

Viral load monitoring in resource-limited settings

(2012) Nathan Ford et al.   AIDS

Second-Line Antiretroviral Treatment Successfully Resuppresses Drug-Resistant HIV-1 After First-Line Failure: Prospective Cohort in Sub-Saharan Africa

(2012) K. C. E. Sigaloff et al.   JOURNAL OF INFECTIOUS DISEASES

Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global collaborative study and meta-regression analysis

(2012) Ravindra K Gupta et al.   LANCET

Long-Lasting Protection of Activity of Nucleoside Reverse Transcriptase Inhibitors and Protease Inhibitors (PIs) by Boosted PI Containing Regimens

(2012) Alexandra U. Scherrer et al.   PLoS One

Accumulation of HIV Drug Resistance Mutations in Patients Failing First-Line Antiretroviral Treatment in South Africa

(2011) Kim C.E. Sigaloff et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Impact of the N348I Mutation in HIV-1 Reverse Transcriptase on Nonnucleoside Reverse Transcriptase Inhibitor Resistance in Non-Subtype B HIV-1

(2011) Adele L. McCormick et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Unnecessary Antiretroviral Treatment Switches and Accumulation of HIV Resistance Mutations; Two Arguments for Viral Load Monitoring in Africa

(2011) Kim C E Sigaloff et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study

(2011) Linda Wittkop et al.   LANCET INFECTIOUS DISEASES

Effect of pretreatment HIV-1 drug resistance on immunological, virological, and drug-resistance outcomes of first-line antiretroviral treatment in sub-Saharan Africa: a multicentre cohort study

(2011) Raph L Hamers et al.   LANCET INFECTIOUS DISEASES

Drug Resistance in Human Immunodeficiency Virus Type-1 Infected Zambian Children Using Adult Fixed Dose Combination Stavudine, Lamivudine, and Nevirapine

(2010) Ravindra K. Gupta et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Viremia, Resuppression, and Time to Resistance in Human Immunodeficiency Virus (HIV) Subtype C during First‐Line Antiretroviral Therapy in South Africa

(2009) Christopher J. Hoffmann et al.   CLINICAL INFECTIOUS DISEASES

Viral Rebound and Emergence of Drug Resistance in the Absence of Viral Load Testing: A Randomized Comparison between Zidovudine‐Lamivudine plus Nevirapine and Zidovudine‐Lamivudine plus Abacavir

(2009) Nicasie Ndembi et al.   JOURNAL OF INFECTIOUS DISEASES

Virological monitoring and resistance to first-line highly active antiretroviral therapy in adults infected with HIV-1 treated under WHO guidelines: a systematic review and meta-analysis

(2009) Ravindra K Gupta et al.   LANCET INFECTIOUS DISEASES

Emergence of Drug Resistance in HIV Type 1–Infected Patients after Receipt of First‐Line Highly Active Antiretroviral Therapy: A Systematic Review of Clinical Trials

(2008) Ravindra Gupta et al.   CLINICAL INFECTIOUS DISEASES