β2 adrenergic receptor–mediated signaling regulates the immunosuppressive potential of myeloid-derived suppressor cells

Manipulation of Ambient Housing Temperature To Study the Impact of Chronic Stress on Immunity and Cancer in Mice

(2019) Bonnie L. Hylander et al.   JOURNAL OF IMMUNOLOGY

Tumor Neurobiology and the War of Nerves in Cancer

(2019) Sam Faulkner et al.   Cancer Discovery

Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression

(2019) Atsunori Kamiya et al.   NATURE NEUROSCIENCE

Myeloid derived-suppressor cells: their role in cancer and obesity

(2018) Suzanne Ostrand-Rosenberg   CURRENT OPINION IN IMMUNOLOGY

Sympathetic Neuronal Activation Triggers Myeloid Progenitor Proliferation and Differentiation

(2018) Sathish Babu Vasamsetti et al.   IMMUNITY

STAT3 in Tumor-Associated Myeloid Cells: Multitasking to Disrupt Immunity

(2018) Yu-Lin Su et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of the nervous system in cancer metastasis

(2018) Nyanbol Kuol et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Blockade of Host β2-Adrenergic Receptor Enhances Graft-versus-Tumor Effect through Modulating APCs

(2018) Hemn Mohammadpour et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Derived Suppressor Cells: Immune-Suppressive Cells That Impair Antitumor Immunity and Are Sculpted by Their Environment

(2018) Suzanne Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Myeloid-derived suppressor cells coming of age

(2018) Filippo Veglia et al.   NATURE IMMUNOLOGY

Transitory presence of myeloid-derived suppressor cells in neonates is critical for control of inflammation

(2018) Yu-Mei He et al.   NATURE MEDICINE

Modulation of anti-tumor immunity by the brain’s reward system

(2018) Tamar L Ben-Shaanan et al.   Nature Communications

Adrenergic Signaling: A Targetable Checkpoint Limiting Development of the Antitumor Immune Response

(2018) Guanxi Qiao et al.   Frontiers in Immunology

Social Stress Mobilizes Hematopoietic Stem Cells to Establish Persistent Splenic Myelopoiesis

(2018) Daniel B. McKim et al.   Cell Reports

Myeloid-Derived Suppressor Cells

(2017) Dmitry I. Gabrilovich   Cancer Immunology Research

Beta blocker use correlates with better overall survival in metastatic melanoma patients and improves the efficacy of immunotherapies in mice

(2017) Kathleen M. Kokolus et al.   OncoImmunology

Sympathetic neural signaling via the β2-adrenergic receptor suppresses T-cell receptor-mediated human and mouse CD8+ T-cell effector function

(2016) Leonardo D. Estrada et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation

(2016) Vinit Kumar et al.   IMMUNITY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice

(2016) Dominic Schmidt et al.   PLoS One

Regulation of Tumor Metastasis by Myeloid-Derived Suppressor Cells

(2015) Thomas Condamine et al.   Annual Review of Medicine

Fas Ligand Deficiency Impairs Tumor Immunity by Promoting an Accumulation of Monocytic Myeloid-Derived Suppressor Cells

(2015) S. Peyvandi et al.   CANCER RESEARCH

Nerve-Cancer Cell Cross-talk: A Novel Promoter of Tumor Progression

(2015) P. Jobling et al.   CANCER RESEARCH

Molecular Mechanisms Underlying β-Adrenergic Receptor-Mediated Cross-Talk between Sympathetic Neurons and Immune Cells

(2015) Dianne Lorton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages

(2015) Stefano Ugel et al.   JOURNAL OF CLINICAL INVESTIGATION

Housing Temperature–Induced Stress Is Suppressing Murine Graft-versus-Host Disease through β2-Adrenergic Receptor Signaling

(2015) Nicholas D. Leigh et al.   JOURNAL OF IMMUNOLOGY

Neural Regulation of Hematopoiesis, Inflammation, and Cancer

(2015) Maher Hanoun et al.   NEURON

Housing temperature-induced stress drives therapeutic resistance in murine tumour models through β2-adrenergic receptor activation

(2015) Jason W.-L. Eng et al.   Nature Communications

A nervous tumor microenvironment: the impact of adrenergic stress on cancer cells, immunosuppression, and immunotherapeutic response

(2014) Jason W.-L. Eng et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Irradiation and anti–PD-L1 treatment synergistically promote antitumor immunity in mice

(2014) Liufu Deng et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/ CD40 Therapy

(2014) J. M. Weiss et al.   JOURNAL OF IMMUNOLOGY

Stressful Presentations: Mild Cold Stress in Laboratory Mice Influences Phenotype of Dendritic Cells in Naïve and Tumor-Bearing Mice

(2014) Kathleen M. Kokolus et al.   Frontiers in Immunology

Deregulation of Apoptotic Factors Bcl-xL and Bax Confers Apoptotic Resistance to Myeloid-derived Suppressor Cells and Contributes to Their Persistence in Cancer

(2013) Xiaolin Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis

(2013) Jeremy D. Waight et al.   JOURNAL OF CLINICAL INVESTIGATION

Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature

(2013) K. M. Kokolus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autonomic Nerve Development Contributes to Prostate Cancer Progression

(2013) C. Magnon et al.   SCIENCE

Structure-Function of the G Protein–Coupled Receptor Superfamily

(2012) Vsevolod Katritch et al.   Annual Review of Pharmacology and Toxicology

Neuroendocrine influences on cancer progression

(2012) Guillermo N. Armaiz-Pena et al.   BRAIN BEHAVIOR AND IMMUNITY

Thermal physiology of laboratory mice: Defining thermoneutrality

(2012) C.J. Gordon   JOURNAL OF THERMAL BIOLOGY

Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasL

(2011) P. Sinha et al.   BLOOD

The beta2-adrenergic receptor on T and B lymphocytes: Do we understand it yet?

(2011) Virginia M. Sanders   BRAIN BEHAVIOR AND IMMUNITY

Molecular Pathways: Beta-Adrenergic Signaling in Cancer: Figure 1.

(2011) Steven W. Cole et al.   CLINICAL CANCER RESEARCH

Epigenetic regulation of beta2-adrenergic receptor expression in TH1 and TH2 cells

(2010) Jaclyn W. McAlees et al.   BRAIN BEHAVIOR AND IMMUNITY

The Sympathetic Nervous System Induces a Metastatic Switch in Primary Breast Cancer

(2010) E. K. Sloan et al.   CANCER RESEARCH

Impact of stress on cancer metastasis

(2010) Myrthala Moreno-Smith et al.   Future Oncology

Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells

(2010) M. G. Lechner et al.   JOURNAL OF IMMUNOLOGY

GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

(2009) Johanna K. Morales et al.   BREAST CANCER RESEARCH AND TREATMENT

Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas

(2008) Y Komohara et al.   JOURNAL OF PATHOLOGY

β2 Adrenergic receptor on T lymphocytes and its clinical implications

(2008) Xuelai Fan et al.   Progress in Natural Science-Materials International