Molecular Mechanisms Underlying β-Adrenergic Receptor-Mediated Cross-Talk between Sympathetic Neurons and Immune Cells

Targeting α- and β-Adrenergic Receptors Differentially Shifts Th1, Th2, and Inflammatory Cytokine Profiles in Immune Organs to Attenuate Adjuvant Arthritis

(2015) Cheri L. Lubahn et al.   Frontiers in Immunology

Autonomic regulation of cellular immune function

(2014) Denise L. Bellinger et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Functionally biased signalling properties of 7TM receptors - opportunities for drug development for the ghrelin receptor

(2013) B Sivertsen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Altered Sympathetic-to-Immune Cell Signaling viaβ2-Adrenergic Receptors in Adjuvant Arthritis

(2013) Dianne Lorton et al.   Clinical & Developmental Immunology

Nuclear Factor κB Mediates Suppression of Canonical Transient Receptor Potential 6 Expression by Reactive Oxygen Species and Protein Kinase C in Kidney Cells

(2013) Yanxia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TLR4 Signaling Augments Monocyte Chemotaxis by Regulating G Protein-Coupled Receptor Kinase 2 Translocation

(2013) Z. Liu et al.   JOURNAL OF IMMUNOLOGY

G Protein-Coupled Receptor Kinase 6 Deficiency Promotes Angiogenesis, Tumor Progression, and Metastasis

(2013) S. K. Raghuwanshi et al.   JOURNAL OF IMMUNOLOGY

GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance

(2013) Michio Nakaya et al.   Nature Communications

Molecular mechanisms of feedback inhibition of protein kinase A on intracellular cAMP accumulation

(2012) Jurgen Vandamme et al.   CELLULAR SIGNALLING

Involvement of Nuclear Factor κB (NF-κB) Signaling Pathway in Regulation of Cardiac G Protein-coupled Receptor Kinase 5 (GRK5) Expression

(2012) Kazi N. Islam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Raf Kinase Inhibitor Protein (RKIP) Dimer Formation Controls Its Target Switch from Raf1 to G Protein-coupled Receptor Kinase (GRK) 2

(2012) Katharina Deiss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2012) Niels Eijkelkamp et al.   MOLECULAR MEDICINE

The role of GRK6 in animal models of Parkinson's Disease and L-DOPA treatment

(2012) Francesca Managò et al.   Scientific Reports

Role of Epac proteins in mechanisms of cAMP-dependent immunoregulation

(2011) S. V. Shirshev   BIOCHEMISTRY-MOSCOW

Cyclic AMP: a selective modulator of NF-κB action

(2011) Sarah Gerlo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inflammatory signaling in macrophages: Transitions from acute to tolerant and alternative activation states

(2011) Lionel B. Ivashkiv   EUROPEAN JOURNAL OF IMMUNOLOGY

PDEs create local domains of cAMP signaling

(2011) Delphine Mika et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Quantifying Ligand Bias at Seven-Transmembrane Receptors

(2011) S. Rajagopal et al.   MOLECULAR PHARMACOLOGY

G protein-coupled receptor kinases: More than just kinases and not only for GPCRs

(2011) Eugenia V. Gurevich et al.   PHARMACOLOGY & THERAPEUTICS

Mammalian Cyclic Nucleotide Phosphodiesterases: Molecular Mechanisms and Physiological Functions

(2011) Sharron H. Francis et al.   PHYSIOLOGICAL REVIEWS

Distinct Phosphorylation Sites on the  2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of  -Arrestin

(2011) K. N. Nobles et al.   Science Signaling

Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling

(2011) Arun K. Shukla et al.   TRENDS IN BIOCHEMICAL SCIENCES

Interleukin-2 receptor downstream events in regulatory T cells: Implications for the choice of immunosuppressive drug therapy

(2010) Robert Zeiser et al.   CELL CYCLE

Signaling through the P38 and ERK pathways: a common link between HIV replication and the immune response

(2010) Robert L. Furler et al.   IMMUNOLOGIC RESEARCH

Distinct Roles of Adenylyl Cyclase VII in Regulating the Immune Responses in Mice

(2010) B. Duan et al.   JOURNAL OF IMMUNOLOGY

Cross Talk between Phosphatidylinositol 3-Kinase and Cyclic AMP (cAMP)-Protein Kinase A Signaling Pathways at the Level of a Protein Kinase B/ -Arrestin/cAMP Phosphodiesterase 4 Complex

(2010) E. Bjorgo et al.   MOLECULAR AND CELLULAR BIOLOGY

Beyond Desensitization: Physiological Relevance of Arrestin-Dependent Signaling

(2010) L. M. Luttrell et al.   PHARMACOLOGICAL REVIEWS

Adenylyl Cyclase-A-kinase Anchoring Protein Complexes: The Next Dimension in cAMP Signaling

(2009) C. W. Dessauer   MOLECULAR PHARMACOLOGY

Targeted transgenesis reveals discrete attenuator functions of GRK and PKA in airway  2-adrenergic receptor physiologic signaling

(2009) W. C. H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclic AMP

(2008) Carlos H. Serezani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

GRK6, a gatekeeper of visceral hyperalgesia

(2008) Cristina Murga et al.   BRAIN BEHAVIOR AND IMMUNITY

Cholesterol-dependent Separation of the β2-Adrenergic Receptor from Its Partners Determines Signaling Efficacy

(2008) Stéphanie M. Pontier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages

(2008) Katie Loniewski et al.   MOLECULAR IMMUNOLOGY