On-chip clearing of arrays of 3-D cell cultures and micro-tissues

Optimizing Imaging of Three-Dimensional Multicellular Tumor Spheroids with Fluorescent Reporter Proteins Using Confocal Microscopy

(2018) Lucia le Roux et al.   Molecular Imaging

Multicellular Tumor Spheroids as an in Vivo–Like Tumor Model for Three-Dimensional Imaging of Chemotherapeutic and Nano Material Cellular Penetration

(2018) Hui-li Ma et al.   Molecular Imaging

Micro-dissected tumor tissues on chip: an ex vivo method for drug testing and personalized therapy

(2016) M. Astolfi et al.   LAB ON A CHIP

Super-Resolution Mapping of Neuronal Circuitry With an Index-Optimized Clearing Agent

(2016) Meng-Tsen Ke et al.   Cell Reports

Core-shell hydrogel beads with extracellular matrix for tumor spheroid formation

(2015) L. Yu et al.   Biomicrofluidics

Clarifying Tissue Clearing

(2015) Douglas S. Richardson et al.   CELL

ScaleS: an optical clearing palette for biological imaging

(2015) Hiroshi Hama et al.   NATURE NEUROSCIENCE

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

(2015) Etsuo A Susaki et al.   Nature Protocols

Designing a Microfluidic Device with Integrated Ratiometric Oxygen Sensors for the Long-Term Control and Monitoring of Chronic and Cyclic Hypoxia

(2015) Samantha Grist et al.   SENSORS

Application and Assessment of Optical Clearing Methods for Imaging of Tissue-Engineered Neural Stem Cell Spheres

(2015) Molly E. Boutin et al.   TISSUE ENGINEERING PART C-METHODS

Scalable and DiI-compatible optical clearance of the mammalian brain

(2015) Bing Hou et al.   Frontiers in Neuroanatomy

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

(2014) Etsuo A. Susaki et al.   CELL

Multilayer Spheroids To Quantify Drug Uptake and Diffusion in 3D

(2014) Toni-Marie Achilli et al.   MOLECULAR PHARMACEUTICS

Microscopy: seeing through tissue

(2014) Vivien Marx   NATURE METHODS

Autophagy modulation as a target for anticancer drug discovery

(2013) Xin Li et al.   ACTA PHARMACOLOGICA SINICA

High-resolution deep imaging of live cellular spheroids with light-sheet-based fluorescence microscopy

(2013) Francesco Pampaloni et al.   CELL AND TISSUE RESEARCH

ClearT: a detergent- and solvent-free clearing method for neuronal and non-neuronal tissue

(2013) T. Kuwajima et al.   DEVELOPMENT

Cells, tissues, and organs on chips: challenges and opportunities for the cancer tumor microenvironment

(2013) Edmond W. K. Young   Integrative Biology

In vivo imaging of zebrafish embryogenesis

(2013) Philipp J. Keller   METHODS

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

(2013) Meng-Tsen Ke et al.   NATURE NEUROSCIENCE

Light microscopy mapping of connections in the intact brain

(2013) Sung-Yon Kim et al.   TRENDS IN COGNITIVE SCIENCES

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

(2013) X Sui et al.   Cell Death & Disease

Chemical Clearing and Dehydration of GFP Expressing Mouse Brains

(2012) Klaus Becker et al.   PLoS One

Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain

(2011) Hiroshi Hama et al.   NATURE NEUROSCIENCE

Two-photon imaging of multicellular tumor spheroids: A novel method for evaluating the efficacy of CDC25 phosphatase inhibitors

(2010) Robert Warden et al.   CANCER BIOLOGY & THERAPY

Deep tissue multiphoton microscopy using longer wavelength excitation

(2009) Demirhan Kobat et al.   OPTICS EXPRESS

Autophagy: Basic Principles and Relevance to Disease

(2008) Mondira Kundu et al.   Annual Review of Pathology-Mechanisms of Disease

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

Hypoxia and Aggressive Tumor Phenotype: Implications for Therapy and Prognosis

(2008) P. Vaupel   ONCOLOGIST

Microscopic imaging techniques for drug discovery

(2007) Andrew Bullen   NATURE REVIEWS DRUG DISCOVERY