Designing a Microfluidic Device with Integrated Ratiometric Oxygen Sensors for the Long-Term Control and Monitoring of Chronic and Cyclic Hypoxia

Alginate core-shell beads for simplified three-dimensional tumor spheroid culture and drug screening

(2015) Linfen Yu et al.   BIOMEDICAL MICRODEVICES

Core-shell hydrogel beads with extracellular matrix for tumor spheroid formation

(2015) L. Yu et al.   Biomicrofluidics

Intermittent Hypoxia Selects for Genotypes and Phenotypes That Increase Survival, Invasion, and Therapy Resistance

(2015) Daniel Verduzco et al.   PLoS One

Low cost referenced luminescent imaging of oxygen and pH with a 2-CCD colour near infrared camera

(2014) Josef Ehgartner et al.   ANALYST

Fabrication and laser patterning of polystyrene optical oxygen sensor films for lab-on-a-chip applications

(2014) S. M. Grist et al.   ANALYST

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium

(2014) Erik O. Pettersen et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Oxygen control with microfluidics

(2014) Martin D. Brennan et al.   LAB ON A CHIP

Ultra-sensitive optical oxygen sensors for characterization of nearly anoxic systems

(2014) Philipp Lehner et al.   Nature Communications

Microfluidic oxygen imaging using integrated optical sensor layers and a color camera

(2013) Birgit Ungerböck et al.   LAB ON A CHIP

Mathematical analysis of oxygen transfer through polydimethylsiloxane membrane between double layers of cell culture channel and gas chamber in microfluidic oxygenator

(2013) Min-Cheol Kim et al.   Microfluidics and Nanofluidics

Islet Preconditioning via Multimodal Microfluidic Modulation of Intermittent Hypoxia

(2012) Joe F. Lo et al.   ANALYTICAL CHEMISTRY

Microtissue size and hypoxia in HTS with 3D cultures

(2012) Amish Asthana et al.   DRUG DISCOVERY TODAY

Construction of oxygen and chemical concentration gradients in a single microfluidic device for studying tumor cell–drug interactions in a dynamic hypoxia microenvironment

(2012) Lei Wang et al.   LAB ON A CHIP

Precise Spatial and Temporal Control of Oxygen within In Vitro Brain Slices via Microfluidic Gas Channels

(2012) Gerardo Mauleon et al.   PLoS One

A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease

(2012) D. K. Wood et al.   Science Translational Medicine

Stable optical oxygen sensing materials based on click-coupling of fluorinated platinum(II) and palladium(II) porphyrins—A convenient way to eliminate dye migration and leaching

(2012) Klaus Koren et al.   SENSORS AND ACTUATORS B-CHEMICAL

Regulating Oxygen Levels in a Microfluidic Device

(2011) Peter C. Thomas et al.   ANALYTICAL CHEMISTRY

Reversible alteration of calcium dynamics in cardiomyocytes during acute hypoxia transient in a microfluidic platform

(2011) S. Martewicz et al.   Integrative Biology

On-chip CO2 control for microfluidic cell culture

(2011) Samuel P. Forry et al.   LAB ON A CHIP

Generation of oxygen gradients in microfluidic devices for cell culture using spatially confined chemical reactions

(2011) Yung-Ann Chen et al.   LAB ON A CHIP

Gene expression and hypoxia in breast cancer

(2011) Elena Favaro et al.   Genome Medicine

Imaging Cycling Tumor Hypoxia

(2010) S. Matsumoto et al.   CANCER RESEARCH

Precise control over the oxygen conditions within the Boyden chamber using a microfabricated insert

(2010) Shawn C. Oppegard et al.   LAB ON A CHIP

Optical Oxygen Sensors for Applications in Microfluidic Cell Culture

(2010) Samantha M. Grist et al.   SENSORS

Light Harvesting as a Simple and Versatile Way to Enhance Brightness of Luminescent Sensors

(2009) Torsten Mayr et al.   ANALYTICAL CHEMISTRY

Culturing Aerobic and Anaerobic Bacteria and Mammalian Cells with a Microfluidic Differential Oxygenator

(2009) Raymond H. W. Lam et al.   ANALYTICAL CHEMISTRY

Hypoxia Helps Glioma to Fight Therapy

(2009) Verena Amberger-Murphy   CURRENT CANCER DRUG TARGETS

The effects of low oxygen on self-renewal and differentiation of embryonic stem cells

(2009) Jeffrey R Millman et al.   Current Opinion in Organ Transplantation

Fine temporal control of the medium gas content and acidity and on-chip generation of series of oxygen concentrations for cell cultures

(2009) Mark Polinkovsky et al.   LAB ON A CHIP

Generation of oxygen gradients with arbitrary shapes in a microfluidic device

(2009) Micha Adler et al.   LAB ON A CHIP

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Modulating Temporal and Spatial Oxygenation over Adherent Cellular Cultures

(2009) Shawn C. Oppegard et al.   PLoS One

The Pervasive Presence of Fluctuating Oxygenation in Tumors

(2008) L. I. Cardenas-Navia et al.   CANCER RESEARCH

The role of oxygen availability in embryonic development and stem cell function

(2008) M. Celeste Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hypoxia and Aggressive Tumor Phenotype: Implications for Therapy and Prognosis

(2008) P. Vaupel   ONCOLOGIST

Ratiometric fiber-optic oxygen sensors based on sol–gel matrix doped with metalloporphyrin and 7-amino-4-trifluoromethyl coumarin

(2008) Chen-Shane Chu et al.   SENSORS AND ACTUATORS B-CHEMICAL

Ratiometric porphyrin-based layers and nanoparticles for measuring oxygen in biosamples

(2008) Piotr J. Cywinski et al.   SENSORS AND ACTUATORS B-CHEMICAL