Vimentin protects cells against nuclear rupture and DNA damage during migration

Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness

(2019) A. Vahabikashi et al.   BIOPHYSICAL JOURNAL

Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins

(2018) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

Quantifying solid stress and elastic energy from excised or in situ tumors

(2018) Hadi T Nia et al.   Nature Protocols

Mechanical principles of nuclear shaping and positioning

(2018) Tanmay P. Lele et al.   JOURNAL OF CELL BIOLOGY

Nuclear rupture at sites of high curvature compromises retention of DNA repair factors

(2018) Yuntao Xia et al.   JOURNAL OF CELL BIOLOGY

Active superelasticity in three-dimensional epithelia of controlled shape

(2018) Ernest Latorre et al.   NATURE

Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA

(2017) Yaming Jiu et al.   JOURNAL OF CELL SCIENCE

Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes

(2017) Amnon Buxboim et al.   MOLECULAR BIOLOGY OF THE CELL

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus

(2017) Andrew D. Stephens et al.   MOLECULAR BIOLOGY OF THE CELL

The molecular architecture of lamins in somatic cells

(2017) Yagmur Turgay et al.   NATURE

Nonlinear Loading-Rate-Dependent Force Response of Individual Vimentin Intermediate Filaments to Applied Strain

(2017) Johanna Block et al.   PHYSICAL REVIEW LETTERS

Squish and squeeze — the nucleus as a physical barrier during migration in confined environments

(2016) Alexandra Lynn McGregor et al.   CURRENT OPINION IN CELL BIOLOGY

Volume regulation and shape bifurcation in the cell nucleus

(2016) Dong-Hwee Kim et al.   JOURNAL OF CELL SCIENCE

Nuclear constriction segregates mobile nuclear proteins away from chromatin

(2016) Jerome Irianto et al.   MOLECULAR BIOLOGY OF THE CELL

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

(2016) M. Raab et al.   SCIENCE

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

Intermediate Filaments: Structure and Assembly

(2016) Harald Herrmann et al.   Cold Spring Harbor Perspectives in Biology

Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration

(2016) Zhuo Gan et al.   Cell Systems

Moving Cell Boundaries Drive Nuclear Shaping during Cell Spreading

(2015) Yuan Li et al.   BIOPHYSICAL JOURNAL

Intermediate Filaments Play a Pivotal Role in Regulating Cell Architecture and Function

(2015) Jason Lowery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell

(2015) Srujana Neelam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CircStat: AMATLABToolbox for Circular Statistics

(2015) Philipp Berens   Journal of Statistical Software

Vimentin Enhances Cell Elastic Behavior and Protects against Compressive Stress

(2014) M.G. Mendez et al.   BIOPHYSICAL JOURNAL

Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments

(2014) Patricia M. Davidson et al.   Cellular and Molecular Bioengineering

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Dynamic signaling by T follicular helper cells during germinal center B cell selection

(2014) Z. Shulman et al.   SCIENCE

Geometric control of vimentin intermediate filaments

(2013) Shagufta H. Shabbir et al.   BIOMATERIALS

The Role of Vimentin Intermediate Filaments in Cortical and Cytoplasmic Mechanics

(2013) Ming Guo et al.   BIOPHYSICAL JOURNAL

Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1

(2013) Daniel E. Conway et al.   CURRENT BIOLOGY

Nesprin-3 connects plectin and vimentin to the nuclear envelope of Sertoli cells but is not required for Sertoli cell function in spermatogenesis

(2013) Mirjam Ketema et al.   MOLECULAR BIOLOGY OF THE CELL

Substrate stiffness regulates solubility of cellular vimentin

(2013) Maria E. Murray et al.   MOLECULAR BIOLOGY OF THE CELL

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Transient nuclear envelope rupturing during interphase in human cancer cells

(2012) Jesse D. Vargas et al.   Nucleus

Cell deformation at the air-liquid interface induces Ca2+-dependent ATP release from lung epithelial cells

(2011) Ronaldo Ramsingh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Vimentin in cancer and its potential as a molecular target for cancer therapy

(2011) Arun Satelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies

(2011) Winnok H. De Vos et al.   HUMAN MOLECULAR GENETICS

Cytoplasmic intermediate filaments mediate actin-driven positioning of the nucleus

(2011) I. Dupin et al.   JOURNAL OF CELL SCIENCE

Vimentin intermediate filaments modulate the motility of mitochondria

(2011) Oxana E. Nekrasova et al.   MOLECULAR BIOLOGY OF THE CELL

Vimentin organization modulates the formation of lamellipodia

(2011) Brian T. Helfand et al.   MOLECULAR BIOLOGY OF THE CELL

The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks

(2010) Asako J. Nakamura et al.   CELL CYCLE

Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

(2010) Melissa G. Mendez et al.   FASEB JOURNAL

Nuclear Lamins

(2010) T. Dechat et al.   Cold Spring Harbor Perspectives in Biology

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL

The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

(2008) T. Shimi et al.   GENES & DEVELOPMENT