Carotenoids as Novel Therapeutic Molecules Against Neurodegenerative Disorders: Chemistry and Molecular Docking Analysis

Effects of Astaxanthin and Docosahexaenoic-Acid-Acylated Astaxanthin on Alzheimer’s Disease in APP/PS1 Double-Transgenic Mice

(2018) Hongxia Che et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Supplementation of lycopene attenuates lipopolysaccharide-induced amyloidogenesis and cognitive impairments via mediating neuroinflammation and oxidative stress

(2018) Jia Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Recent Advances in Studies on the Therapeutic Potential of Dietary Carotenoids in Neurodegenerative Diseases

(2018) Kyoung Sang Cho et al.   Oxidative Medicine and Cellular Longevity

A global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health

(2018) Manuel Rodriguez-Concepcion et al.   PROGRESS IN LIPID RESEARCH

Targeting Oligomers in Neurodegenerative Disorders: Lessons from α-Synuclein, Tau, and Amyloid-β Peptide

(2018) Bharathi Shrikanth Gadad et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative Genome Damage and its Repair in Neurodegenerative Diseases: Function of Transition Metals as a Double-Edged Sword

(2018) Muralidhar L. Hegde et al.   JOURNAL OF ALZHEIMERS DISEASE

Fucoxanthin Inhibits β-Amyloid Assembly and Attenuates β-Amyloid Oligomer-Induced Cognitive Impairments

(2017) Siying Xiang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer’s Disease

(2017) Johant Lakey-Beitia et al.   JOURNAL OF ALZHEIMERS DISEASE

Anti-amyloid aggregation activity of novel carotenoids: implications for Alzheimer’s drug discovery

(2017) Johant Lakey-Beitia et al.   Clinical Interventions in Aging

Differential Accumulation of Secreted AβPP Metabolites in Ocular Fluids

(2017) Annamalai Prakasam et al.   JOURNAL OF ALZHEIMERS DISEASE

Kinetics and molecular docking studies of fucosterol and fucoxanthin, BACE1 inhibitors from brown algae Undaria pinnatifida and Ecklonia stolonifera

(2016) Hyun Ah Jung et al.   FOOD AND CHEMICAL TOXICOLOGY

Deposition Form and Bioaccessibility of Keto-carotenoids from Mamey Sapote (Pouteria sapota), Red Bell Pepper (Capsicum annuum), and Sockeye Salmon (Oncorhynchus nerka) Filet

(2016) Tania Chacón-Ordóñez et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Reaction of Paprika Carotenoids, Capsanthin and Capsorubin, with Reactive Oxygen Species

(2016) Azusa Nishino et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Guide for Carotenoid Identification in Biological Samples

(2016) Sol Maiam Rivera Vélez   JOURNAL OF NATURAL PRODUCTS

Neuronal response in Alzheimer’s and Parkinson’s disease: the effect of toxic proteins on intracellular pathways

(2015) Shohreh Majd et al.   BMC NEUROSCIENCE

Isolation of β-Cryptoxanthin-epoxides, Precursors of Cryptocapsin and 3′-Deoxycapsanthin, from Red Mamey (Pouteria sapota)

(2015) Erika Turcsi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lycopene abrogates Aβ(1–42)-mediated neuroinflammatory cascade in an experimental model of Alzheimer’s disease

(2015) Anand Kamal Sachdeva et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Simultaneous Determination of Fucoxanthin and Its Deacetylated Metabolite Fucoxanthinol in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry

(2015) Yiping Zhang et al.   Marine Drugs

Redox Status and Neuro Inflammation Indexes in Cerebellum and Motor Cortex of Wistar Rats Supplemented with Natural Sources of Omega-3 Fatty Acids and Astaxanthin: Fish Oil, Krill Oil, and Algal Biomass

(2015) Tatiana Polotow et al.   Marine Drugs

PubChem Substance and Compound databases

(2015) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Structure-Based Peptide Design to Modulate Amyloid Beta Aggregation and Reduce Cytotoxicity

(2015) Jitendra Kumar et al.   PLoS One

Emerging Therapeutics for Alzheimer's Disease

(2014) Karen Chiang et al.   Annual Review of Pharmacology and Toxicology

Phase II enzyme induction by a carotenoid, lutein, in a PC12D neuronal cell line

(2014) Seiji Miyake et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Carotenoids and flavonoids synergistically attenuate inflammation in endothelial cells induced by TNF-α

(2014) Talya Wolak et al.   Journal of the American Society of Hypertension

Carotenoids inhibit lipid peroxidation and hemoglobin oxidation, but not the depletion of glutathione induced by ROS in human erythrocytes

(2014) Renan Campos Chisté et al.   LIFE SCIENCES

Polyphenols as Therapeutic Molecules in Alzheimer’s Disease Through Modulating Amyloid Pathways

(2014) Johant Lakey-Beitia et al.   MOLECULAR NEUROBIOLOGY

Review of methods for analysis of carotenoids

(2014) K.T. Amorim-Carrilho et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

3-β-Glucosyl-3′-β-quinovosyl zeaxanthin, a novel carotenoid glycoside synthesized by Escherichia coli cells expressing the Pantoea ananatis carotenoid biosynthesis gene cluster

(2013) Seon-Kang Choi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Saffron and natural carotenoids: Biochemical activities and anti-tumor effects

(2013) Azam Bolhassani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Mechanistic Aspects of Carotenoid Biosynthesis

(2013) Alexander R. Moise et al.   CHEMICAL REVIEWS

Cryptocapsinepoxide-Type Carotenoids from Red Mamey, Pouteria sapota

(2013) Gergely Gulyás-Fekete et al.   JOURNAL OF NATURAL PRODUCTS

Clinical Trials in Predementia Stages of Alzheimer Disease

(2013) Jagan A. Pillai et al.   MEDICAL CLINICS OF NORTH AMERICA

Treatment Strategies Targeting Amyloid  -Protein

(2013) D. Schenk et al.   Cold Spring Harbor Perspectives in Medicine

Cholinestrase inhibitory effects of geranylated flavonoids from Paulownia tomentosa fruits

(2012) Jung Keun Cho et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

(2012) I. W. Hamley   CHEMICAL REVIEWS

Native carotenoids composition of some tropical fruits

(2012) Enrique Murillo et al.   FOOD CHEMISTRY

Review of Theoretical Studies for Prediction of Neurodegenerative Inhibitors

(2012) F. Prado-Prado et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Recent Advances in α-Synuclein Functions, Advanced Glycation, and Toxicity: Implications for Parkinson’s Disease

(2012) Erika Guerrero et al.   MOLECULAR NEUROBIOLOGY

Hydrophilic Carotenoids: Recent Progress

(2012) Magdolna Háda et al.   MOLECULES

Carotenoids and DNA damage

(2012) Amaya Azqueta et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Exploring the inhibitory activity of short-chain phospholipids against amyloid fibrillogenesis of hen egg-white lysozyme

(2011) Steven S.-S. Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Amyloid β-induced erythrocytic damage and its attenuation by carotenoids

(2011) Kiyotaka Nakagawa et al.   FEBS LETTERS

Protective Effects of Anthocyanins against Amyloid β-Peptide-Induced Damage in Neuro-2A Cells

(2011) Ping-Hsiao Shih et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bioaccessibility of Carotenoids and Vitamin E from Pasta: Evaluation of an in Vitro Digestion Model

(2011) Susanne Werner et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Apricot Carotenoids Possess Potent Anti-amyloidogenic Activity in Vitro

(2011) Shigeru Katayama et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Sapotexanthin, an A-Provitamin Carotenoid from Red Mamey (Pouteria sapota)

(2011) Enrique Murillo et al.   JOURNAL OF NATURAL PRODUCTS

Carotenoids in Algae: Distributions, Biosyntheses and Functions

(2011) Shinichi Takaichi   Marine Drugs

Aβ(42) induced MRI changes in aged rabbit brain resembles AD brain

(2011) B.N. Ramesh et al.   NEUROCHEMISTRY INTERNATIONAL

Carotenoids and Alzheimer’s Disease: An insight into therapeutic role of retinoids in animal models

(2011) M. Obulesu et al.   NEUROCHEMISTRY INTERNATIONAL

The first synthesis of PEG–carotenoid conjugates

(2011) Magdolna Háda et al.   TETRAHEDRON LETTERS

Dietary carotenoid lutein protects against DNA damage and alterations of the redox status induced by cisplatin in human derived HepG2 cells

(2011) Juliana Mara Serpeloni et al.   TOXICOLOGY IN VITRO

Towards Carotenoid Dendrimers: Carotenoid Diesters and Triesters with Aromatic Cores

(2010) Magdolna Háda et al.   HELVETICA CHIMICA ACTA

Neuroprotective Effects of Astaxanthin in Oxygen-Glucose Deprivation in SH-SY5Y Cells and Global Cerebral Ischemia in Rat

(2010) Dae-Hee Lee et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Anti-amyloidogenic property of leaf aqueous extract of Caesalpinia crista

(2010) B.N. Ramesh et al.   NEUROSCIENCE LETTERS

Amyloid fibrils

(2010) Roma N. Rambaran et al.   Prion

Antioxidant potential of meso-zeaxanthin a semi synthetic carotenoid

(2009) Alikkunjhi P. Firdous et al.   FOOD CHEMISTRY

Expression ofphytoene synthase1and Carotene DesaturasecrtIGenes Result in an Increase in the Total Carotenoids Content in Transgenic Elite Wheat (Triticum aestivumL.)

(2009) Ling Cong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A traditional medicinal herbPaeonia suffruticosaand its active constituent 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose have potent anti-aggregation effects on Alzheimer’s amyloid β proteinsin vitroandin vivo

(2009) Hironori Fujiwara et al.   JOURNAL OF NEUROCHEMISTRY

Beta-Secretase: Structure, Function, and Evolution

(2008) Chitra Venugopal et al.   CNS & Neurological Disorders-Drug Targets

Carotenoids: Actual knowledge on food sources, intakes, stability and bioavailability and their protective role in humans

(2008) Giuseppe Maiani et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Biomarker discovery in neurodegenerative diseases: A proteomic approach

(2008) Min Shi et al.   NEUROBIOLOGY OF DISEASE

A Carotenoid Algal Preparation Containing Phytoene and Phytofluene Inhibited LDL Oxidation In Vitro

(2008) Aviv Shaish et al.   PLANT FOODS FOR HUMAN NUTRITION

Efficient Inhibition of the Alzheimer's Disease  -Secretase by Membrane Targeting

(2008) L. Rajendran et al.   SCIENCE

Dicarotenoid esters of bivalent acids

(2008) Magdolna Háda et al.   TETRAHEDRON LETTERS

Geranylgeranyl pyrophosphate stimulates γ-secretase to increase the generation of Aβ and APP-CTFγ

(2007) Yan Zhou et al.   FASEB JOURNAL