Review
Nutrition & Dietetics
Aneta Otocka-Kmiecik
Summary: Paraoxonase 1 (PON1) is an antioxidant enzyme that is associated with HDL and has potential anti-atherogenic effects. Carotenoids, such as astaxanthin, beta-carotene, and lycopene, can increase PON1 activity and gene expression by quenching singlet oxygen and scavenging free radicals. Understanding the mechanisms by which carotenoids modulate PON1 may lead to the development of targeted therapies for cardiovascular diseases.
Article
Biochemistry & Molecular Biology
Yuanhao Chen, Hong Du, Honghao Liang, Ting Hong, Tangcheng Li
Summary: Chlamydomonas reinhardtii was transformed with BKT genes from Phaffia rhodozyma (PrBKT) and Chlamydomonas reinhardtii (CrBKT), resulting in the stable transformed algal strains C18 and P1. The total carotenoid content of C18 and P1 was 2.13-fold and 2.20-fold higher than that of the WT, respectively. Transcriptome and metabolome analysis revealed that overexpression of PrBKT in Chlamydomonas reinhardtii up-regulated more genes in the carotenoid pathway metabolism compared to CrBKT, indicating a structural difference between the two BKT genes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Medicinal
Konstantin Chekanov
Summary: This article reviews the existing data on microalgal species known as potential carotenoid producers in biotechnology. It includes well-known species like Haematococcus and Dunaliella, as well as lesser-known representatives. Their distribution covers Europe from the Greek Mediterranean coast in the south to snow valleys in Norway in the north, and from ponds in Portugal to saline lakes and mountains in Ukraine. A wide range of algal secondary carotenoids are reviewed, including beta-carotene, astaxanthin, canthaxanthin, echinenone, adonixanthin, and adonirubin. The main concepts of carotenoid-producing algae biology are briefly explained for convenience.
Article
Biology
Konstantin Chekanov, Daniil Litvinov, Tatiana Fedorenko, Olga Chivkunova, Elena Lobakova
Summary: Microalgae are rich sources of natural carotenoids, including the valuable pigments astaxanthin and beta-carotene, which are essential components of various industries. A new strain of green microalga, Bracteacoccus aggregatus BM5/15, was characterized for its simultaneous production of these carotenoids, showing potential for industrial-scale cultivation. The study provides valuable data on growth parameters, microscopic observations, pigment and fatty acid profiles, and proposes possible pathways of astaxanthin synthesis based on carotenoid composition.
Article
Biotechnology & Applied Microbiology
Ling Li, Xiuyang Tang, Yangyang Luo, Xuechao Hu, Lujing Ren
Summary: This study explored the effect of different abiotic stresses on carotenoid production and found that low temperature, ferric ion, glucose and monosodium glutamate ratio, and micro-oxygen supply conditions can all regulate the accumulation of carotenoids.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2022)
Article
Engineering, Chemical
Cassamo U. Mussagy, Fabiane O. Farias, Niura M. Bila, Maria J. S. M. Giannini, Jorge F. B. Pereira, Valeria C. Santos-Ebinuma, Adalberto Pessoa Jr
Summary: This study proposes a biocompatible method using ionic liquids (ILs) for the selective recovery of beta-carotene and astaxanthin from Phaffia rhodozyma cells. The most efficient IL solution was identified and an integrated platform for solvent recycling and biomolecule recovery was developed. The results demonstrate the efficacy of ILs for one-step extraction of beta-carotene and astaxanthin from microbial-based biomass.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Toru Yoshimi, Sakiko Hashimoto, Yuki Kubo, Masato Takeuchi, Daichi Morimoto, Satoshi Nakagawa, Shigeki Sawayama
Summary: By overexpressing a crtZ candidate gene, astaxanthin production in A.limacinum was significantly increased, suggesting a potential pathway via cantaxanthin for astaxanthin biosynthesis. Additionally, longer light exposure was found to enhance astaxanthin production while reducing beta-carotene content in the wild-type strain, highlighting the importance of light exposure duration for astaxanthin production in A.limacinum. Further investigations are needed to fully understand the astaxanthin biosynthetic process in A.limacinum.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Hang-Zhi Zhu, Shan Jiang, Jun-Jie Wu, Xue-Rong Zhou, Peng-Yang Liu, Feng-Hong Huang, Xia Wan
Summary: This study successfully engineered Yarrowia lipolytica to produce high levels of 3S,3'S-astaxanthin, providing potential for industrial production and laying the foundation for a sustainable biorefinery platform.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Hanyu Liang, Hongjuan Chen, Xinya Liu, Zihan Wang, Pengfu Li, Shan Lu
Summary: This study aims to investigate the synthesis mechanism of astaxanthin and suggests that the hydroxylation step may be the bottleneck for heterologous production of astaxanthin in Synechocystis.
Article
Biotechnology & Applied Microbiology
Benjamin W. Hall, Wayne S. Kontur, Jeanette C. Neri, Derek M. Gille, Daniel R. Noguera, Timothy J. Donohue
Summary: In this study, it was found that N. aromaticivorans can naturally produce various carotenoids and their production can be enhanced through gene deletion and heterologous expression. The levels of carotenoids were not significantly affected by oxygen concentration and they could be produced in significant amounts when grown in pretreated lignocellulosic biomass. These findings suggest that N. aromaticivorans has the potential to simultaneously produce valuable intracellular and extracellular commodities.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2023)
Article
Cell Biology
Hao-Hong Chen, Yu-Jing He, Ming-Hua Liang, Bing Yan, Jian-Guo Jiang
Summary: This study demonstrated that Dunaliella salina is capable of synthesizing astaxanthin, but the low expression of the enzyme DsBKT catalyzing this synthesis under both normal and stress conditions prevents D. salina from accumulating astaxanthin efficiently.
JOURNAL OF CELLULAR PHYSIOLOGY
(2022)
Article
Plant Sciences
Ming-Xia He, Jie-Lin Wang, Yuan-Yuan Lin, Jun-Chao Huang, Ai-Zhong Liu, Feng Chen
Summary: This study genetically engineered Camelina sativa to produce red ketocarotenoids as a reporter gene, allowing visualization of transgenic events without the use of traditional selection marker genes. The transgenic seed oils exhibited higher antioxidant activity.
PLANT CELL REPORTS
(2022)
Article
Fisheries
Samia Fawzy, Weilong Wang, Yue Zhou, Yucai Xue, Ganfeng Yi, Meiqin Wu, Xuxiong Huang
Summary: The study aimed to investigate the effect of dietary beta-carotene and astaxanthin on the performances of white shrimp. The results showed that white shrimp fed beta-carotene at 300-400 mg/kg had higher growth performance and survival compared to other beta-carotene treatments. The redness of the shrimp increased with the increase in beta-carotene level. The combination of beta-carotene and astaxanthin resulted in the highest shell astaxanthin content. The diets containing carotenoids significantly improved the total antioxidant capacity and malondialdehyde content in the shrimp.
AQUACULTURE REPORTS
(2022)
Article
Food Science & Technology
Jing Wang, Xinge Hu, Junbin Chen, Tiannan Wang, Xianju Huang, Guoxun Chen
Summary: Beta-carotene, an important carotenoid, can be extracted from microalgae and has been found to have biological activities such as promoting lifespan and reducing oxidative stress. However, further studies are needed to explore the health benefits and functional mechanisms of beta-carotene in microalgae extracts.
Article
Biotechnology & Applied Microbiology
Kunmei Huang, Zhongliang Su, Mingyan He, Yaoyao Wu, Meiqi Wang
Summary: The beta-carotene hydroxylase gene from Haematococcus pluvialis has a positive regulatory effect on pigments in Chlamydomonas reinhardtii, and high light stress can enhance pigment accumulation in transgenic C. reinhardtii.
BIOTECHNOLOGY LETTERS
(2022)
Review
Biotechnology & Applied Microbiology
Manpreet Sandhu, Shabir H. Wani, Victor M. Jimenez
PLANT CELL TISSUE AND ORGAN CULTURE
(2018)
Correction
Biotechnology & Applied Microbiology
Manpreet Sandhu, Shabir H. Wani, Victor M. Jimenez
PLANT CELL TISSUE AND ORGAN CULTURE
(2018)
Article
Food Science & Technology
Andrea Irias-Mata, Victor M. Jimenez, Christof Bjorn Steingass, Ralf M. Schweiggert, Reinhold Carle, Patricia Esquivel
FOOD RESEARCH INTERNATIONAL
(2018)
Article
Food Science & Technology
Roland Schex, Veronika M. Lieb, Victor M. Jimenez, Patricia Esquivel, Ralf M. Schweiggert, Reinhold Carle, Christof B. Steingass
FOOD RESEARCH INTERNATIONAL
(2018)
Article
Horticulture
Maria Vinas, Juan C. Mendez, Victor M. Jimenez
SCIENTIA HORTICULTURAE
(2020)
Article
Agronomy
Jose David Alfaro-Solis, Alexander Montoya-Arroyo, Victor M. Jimenez, Elizabeth Arnaez-Serrano, Jason Perez, Walter Vetter, Jan Frank, Iris Lewandowski
AGROFORESTRY SYSTEMS
(2020)
Article
Chemistry, Applied
Sevcan Ersan, Julia C. Berning, Patricia Esquivel, Victor M. Jimenez, Reinhold Carle, Bianca May, Ralf Schweiggert, Christof B. Steingass
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2020)
Article
Chemistry, Applied
Alexander Montoya-Arroyo, Jose David Alfaro-Solis, Patricia Esquivel, Victor M. Jimenez, Jan Frank
Summary: The study found significant differences in vitamin E content and composition of Acrocomia aculeata fruits from different regions in Costa Rica. The mesocarp was dominated by tocotrienols, while no tocopherols were found in the endosperm. The region with the most tropical climatic conditions had the highest vitamin E content observed.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Food Science & Technology
Catalina Acuna-Gutierrez, Steffen Schock, Victor M. Jimenez, Joachim Mueller
Summary: This study evaluated the feasibility of detecting fumonisin B-1 (FB1) in beans using NIRS technology and demonstrated the effectiveness of this method through controlled contamination experiments. The results showed that using the spread contamination method and grinding the sample achieved better linear adjustment, potentially serving as an important approach for future rapid detection techniques.
Article
Chemistry, Applied
Alexander Montoya-Arroyo, Katja Lehnert, Peter E. Lux, Victor M. Jimenez, Patricia Esquivel, Ana Margarita Silva-Benavides, Walter Vetter, Jan Frank
Summary: This study identified 11'-alpha-tocomonoenol as the predominant form of tocochromanol in cyanobacteria and microalgae, particularly Tetraselmis sp., and reported its presence in aquatic photosynthetic organisms for the first time.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Review
Food Science & Technology
Catalina Acuna-Gutierrez, Victor M. Jimenez, Joachim Mueller
Summary: This review summarizes the analysis and occurrence of mycotoxins in pulses, emphasizing the impact of climatic conditions on microorganism infestation and mycotoxin accumulation. It also explores the potential correlation between fungal infection and mycotoxin incidence in pulses. The review further discusses the potential effect of certain compounds on reducing fungi infestation and mycotoxin accumulation. It highlights the negative consequences of mycotoxin accumulation on the physiology and development of contaminated seeds and seedlings.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2022)
Article
Plant Sciences
Jorge Warner, Yesly Camacho-Solis, Victor M. Jimenez
Summary: This study describes direct and indirect shoot regeneration in Vanilla odorata and indirect regeneration in V. pompona for the first time. The results show that stem nodal segments and callus from both species have high regenerative potential under different culture conditions. Histological analysis also reveals the presence of calcium oxalate raphides in the callus. The findings of this study provide a foundation for large-scale propagation efforts and other biotechnological applications of Vanilla odorata and V. pompona.
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT
(2023)
Review
Food Science & Technology
Patricia Esquivel, Jessie Usaga, Ralf Schweiggert, Christof B. Steingass, Victor M. Jimenez
Summary: This review compiles the current state of knowledge on the effects of thermal and nonthermal processing and fermentation on selected compounds in potentially health-promoting tropical fruit juices. It discusses the functional properties of pineapple, pitaya, guava, and papaya fruits and the impact of processing techniques on the retention of their functional constituents.
ACS FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Food Science & Technology
Patricia Esquivel, Maria Vinas, Christof B. Steingass, Maike Gruschwitz, Eric Guevara, Reinhold Carle, Ralf M. Schweiggert, Victor M. Jimenez
FRONTIERS IN SUSTAINABLE FOOD SYSTEMS
(2020)
Article
Agronomy
Dessiree Zerpa-Catanho, Andres Hernandez-Pridybailo, Viviana Madrigal-Ortiz, Adonay Zunga-Centeno, Carolina Porras-Martinez, Victor M. Jimenez, Luis Barboza-Barquero
JOURNAL OF CROP IMPROVEMENT
(2019)