Receptor Heterodimerization and Co-Receptor Engagement in TLR2 Activation Induced by MIC1 and MIC4 from Toxoplasma gondii

The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming

(2019) Aline Sardinha-Silva et al.   PLoS Pathogens

CD14 is critical for TLR2-mediated M1 macrophage activation triggered by N-glycan recognition

(2017) Thiago Aparecido da Silva et al.   Scientific Reports

Targeting and Recognition of Toll-Like Receptors by Plant and Pathogen Lectins

(2017) Rafael Ricci-Azevedo et al.   Frontiers in Immunology

Synthesis and evaluation of a desymmetrised synthetic lectin: an approach to carbohydrate receptors with improved versatility

(2016) Tiddo J. Mooibroek et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Lipophosphoglycans from Leishmania amazonensis Strains Display Immunomodulatory Properties via TLR4 and Do Not Affect Sand Fly Infection

(2016) Paula M. Nogueira et al.   PLoS Neglected Tropical Diseases

Toll-like receptor co-receptors as master regulators of the immune response

(2015) Marco Di Gioia et al.   MOLECULAR IMMUNOLOGY

Research advances in microneme protein 3 of Toxoplasma gondii

(2015) Yanhua Wang et al.   Parasites & Vectors

Differential Impact of LPG-and PG-Deficient Leishmania major Mutants on the Immune Response of Human Dendritic Cells

(2015) Michelle A. Favila et al.   PLoS Neglected Tropical Diseases

Vaccination with Recombinant Microneme Proteins Confers Protection against Experimental Toxoplasmosis in Mice

(2015) Camila Figueiredo Pinzan et al.   PLoS One

TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages and the Th1 immune response in vivo and in vitro

(2014) Jia-Yun Li et al.   Cellular & Molecular Immunology

Incidence, immunological and clinical characteristics of reactivation of latent Toxoplasma gondii infection in HIV-infected patients

(2014) P. KODYM et al.   EPIDEMIOLOGY AND INFECTION

Toxoplasma gondii-Derived Profilin Triggers Human Toll-Like Receptor 5-Dependent Cytokine Production

(2014) Rosa Maria Salazar Gonzalez et al.   Journal of Innate Immunity

Recognition of TLR2 N-Glycans: Critical Role in ArtinM Immunomodulatory Activity

(2014) Vania Sammartino Mariano et al.   PLoS One

Therapeutic Administration of Recombinant Paracoccin Confers Protection against Paracoccidioides brasiliensis Infection: Involvement of TLRs

(2014) Ana Claudia Paiva Alegre-Maller et al.   PLoS Neglected Tropical Diseases

Multimeric Assembly of Host-Pathogen Adhesion Complexes Involved in Apicomplexan Invasion

(2014) May M. Paing et al.   PLoS Pathogens

Toll-Like Receptor Signaling Pathways

(2014) Takumi Kawasaki et al.   Frontiers in Immunology

Combined Action of Nucleic Acid-Sensing Toll-like Receptors and TLR11/TLR12 Heterodimers Imparts Resistance to Toxoplasma gondii in Mice

(2013) Warrison A. Andrade et al.   Cell Host & Microbe

Binding sugars: from natural lectins to synthetic receptors and engineered neolectins

(2013) Julie Arnaud et al.   CHEMICAL SOCIETY REVIEWS

CD14 Protein Acts as an Adaptor Molecule for the Immune Recognition ofSalmonellaCurli Fibers

(2013) Glenn J. Rapsinski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors

(2013) Jeroen van Bergenhenegouwen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Protective immunity induced by a DNA vaccine-encoding Toxoplasma gondii microneme protein 11 against acute toxoplasmosis in BALB/c mice

(2013) Qing Tao et al.   PARASITOLOGY RESEARCH

Lysophosphatidylcholine Triggers TLR2- and TLR4-Mediated Signaling Pathways but Counteracts LPS-Induced NO Synthesis in Peritoneal Macrophages by Inhibiting NF-κB Translocation and MAPK/ERK Phosphorylation

(2013) Alan Brito Carneiro et al.   PLoS One

Cell type-specific function of TAK1 in innate immune signaling

(2013) Adebusola A. Ajibade et al.   TRENDS IN IMMUNOLOGY

Evaluation of protective effect of pVAX-TgMIC13 plasmid against acute and chronic Toxoplasma gondii infection in a murine model

(2013) Zi-Guo Yuan et al.   VACCINE

Epidemiology of and Diagnostic Strategies for Toxoplasmosis

(2012) F. Robert-Gangneux et al.   CLINICAL MICROBIOLOGY REVIEWS

Recognition of Profilin by Toll-like Receptor 12 Is Critical for Host Resistance to Toxoplasma gondii

(2012) A. Alicia Koblansky et al.   IMMUNITY

Galactose Recognition by the Apicomplexan ParasiteToxoplasma gondii

(2012) Jan Marchant et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of TLR5-Flagellin Recognition and Signaling

(2012) S.-i. Yoon et al.   SCIENCE

Structural Biology of the Toll-Like Receptor Family

(2011) Jin Young Kang et al.   Annual Review of Biochemistry

What the Myddosome structure tells us about the initiation of innate immunity

(2011) Nicholas J. Gay et al.   TRENDS IN IMMUNOLOGY

Innate responses to Toxoplasma gondii in mice and humans

(2011) Reed Pifer et al.   TRENDS IN PARASITOLOGY

Sialic acids: Key determinants for invasion by the Apicomplexa

(2010) Nikolas Friedrich et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Detection of Mycoplasma in cell cultures

(2010) Lesley Young et al.   Nature Protocols

Toxoplasma gondii microneme protein 8 (MIC8) is a potential vaccine candidate against toxoplasmosis

(2010) M. M. Liu et al.   PARASITOLOGY RESEARCH

Stimulation of IFN-γ production by garlic lectin in mouse spleen cells: Involvement of IL-12 via activation of p38 MAPK and ERK in macrophages

(2010) Qing Dong et al.   PHYTOMEDICINE

A Method for Generation of Bone Marrow-Derived Macrophages from Cryopreserved Mouse Bone Marrow Cells

(2010) Fernanda M. Marim et al.   PLoS One

A truncated lipoglycan from mycobacteria with altered immunological properties

(2010) H. L. Birch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Difficulties and Perspectives of Immunomodulatory Therapy with Mistletoe Lectins and Standardized Mistletoe Extracts in Evidence-Based Medicine

(2009) Tibor Hajtó et al.   Evidence-based Complementary and Alternative Medicine

Members of a Novel Protein Family Containing Microneme Adhesive Repeat Domains Act as Sialic Acid-binding Lectins during Host Cell Invasion by Apicomplexan Parasites

(2009) Nikolas Friedrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Synthetic lectins

(2009) Anthony P. Davis   ORGANIC & BIOMOLECULAR CHEMISTRY

Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2

(2009) Maximiliano J. Jimenez-Dalmaroni et al.   PLoS One

Toxoplasma gondii microneme protein 6 (MIC6) is a potential vaccine candidate against toxoplasmosis in mice

(2009) Gao-Hui Peng et al.   VACCINE

Toll-like receptors and their role in host resistance to Toxoplasma gondii

(2008) Felix Yarovinsky   IMMUNOLOGY LETTERS

Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies

(2008) Kristina E.M. Persson et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36

(2008) Nadra J. Nilsen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

(2008) L. Liu et al.   SCIENCE