The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming
Authors
Keywords
Parasitic diseases, Toxoplasma gondii, Cytokines, Lectins, Toll-like receptors, Macrophages, Protozoan infections, Immune cells
Journal
PLoS Pathogens
Volume 15, Issue 6, Pages e1007871
Publisher
Public Library of Science (PLoS)
Online
2019-06-22
DOI
10.1371/journal.ppat.1007871
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Secretory Microneme Proteins Induce T-Cell Recall Responses in Mice Chronically Infected with Toxoplasma gondii
- (2019) Iti Saraav et al. mSphere
- Toxoplasma gondiiTgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses
- (2016) Gabrielle Gay et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lipophosphoglycans from Leishmania amazonensis Strains Display Immunomodulatory Properties via TLR4 and Do Not Affect Sand Fly Infection
- (2016) Paula M. Nogueira et al. PLoS Neglected Tropical Diseases
- Paracoccin Induces M1 Polarization of Macrophages via Interaction with TLR4
- (2016) Mateus S. Freitas et al. Frontiers in Microbiology
- Identification of a TNF-α inducer MIC3 originating from the microneme of non-cystogenic, virulent Toxoplasma gondii
- (2016) Jingfan Qiu et al. Scientific Reports
- Toxoplasma gondii GRA7-Induced TRAF6 Activation Contributes to Host Protective Immunity
- (2015) Chul-Su Yang et al. INFECTION AND IMMUNITY
- Evidence for Conformational Mechanism on the Binding of TgMIC4 with β-Galactose-Containing Carbohydrate Ligand
- (2015) Adriano Santos et al. LANGMUIR
- Differential Impact of LPG-and PG-Deficient Leishmania major Mutants on the Immune Response of Human Dendritic Cells
- (2015) Michelle A. Favila et al. PLoS Neglected Tropical Diseases
- Vaccination with Recombinant Microneme Proteins Confers Protection against Experimental Toxoplasmosis in Mice
- (2015) Camila Figueiredo Pinzan et al. PLoS One
- Selective and strain-specific NFAT4 activation by theToxoplasma gondiipolymorphic dense granule protein GRA6
- (2014) Ji Su Ma et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Recognition of TLR2 N-Glycans: Critical Role in ArtinM Immunomodulatory Activity
- (2014) Vania Sammartino Mariano et al. PLoS One
- Therapeutic Administration of Recombinant Paracoccin Confers Protection against Paracoccidioides brasiliensis Infection: Involvement of TLRs
- (2014) Ana Claudia Paiva Alegre-Maller et al. PLoS Neglected Tropical Diseases
- Multimeric Assembly of Host-Pathogen Adhesion Complexes Involved in Apicomplexan Invasion
- (2014) May M. Paing et al. PLoS Pathogens
- Combined Action of Nucleic Acid-Sensing Toll-like Receptors and TLR11/TLR12 Heterodimers Imparts Resistance to Toxoplasma gondii in Mice
- (2013) Warrison A. Andrade et al. Cell Host & Microbe
- Expression of recombinant glycoproteins in mammalian cells: towards an integrative approach to structural biology
- (2013) A Radu Aricescu et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The immunomodulatory effect of plant lectins: a review with emphasis on ArtinM properties
- (2013) Maria A. Souza et al. GLYCOCONJUGATE JOURNAL
- AToxoplasmadense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation
- (2013) Laurence Braun et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lysophosphatidylcholine Triggers TLR2- and TLR4-Mediated Signaling Pathways but Counteracts LPS-Induced NO Synthesis in Peritoneal Macrophages by Inhibiting NF-κB Translocation and MAPK/ERK Phosphorylation
- (2013) Alan Brito Carneiro et al. PLoS One
- Recognition of Profilin by Toll-like Receptor 12 Is Critical for Host Resistance to Toxoplasma gondii
- (2012) A. Alicia Koblansky et al. IMMUNITY
- Galactose Recognition by the Apicomplexan ParasiteToxoplasma gondii
- (2012) Jan Marchant et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modulation of innate immunity by Toxoplasma gondii virulence effectors
- (2012) Christopher A. Hunter et al. NATURE REVIEWS MICROBIOLOGY
- Plant lectins are novel Toll-like receptor agonists
- (2011) John Unitt et al. BIOCHEMICAL PHARMACOLOGY
- Strain-specific activation of the NF-κB pathway by GRA15, a novelToxoplasma gondiidense granule protein
- (2011) Emily E. Rosowski et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Detection of Mycoplasma in cell cultures
- (2010) Lesley Young et al. Nature Protocols
- Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection
- (2009) Guillaume Oldenhove et al. IMMUNITY
- Intravenous immunoglobulin contains a broad repertoire of anticarbohydrate antibodies that is not restricted to the IgG2 subclass
- (2009) Stephan von Gunten et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Members of a Novel Protein Family Containing Microneme Adhesive Repeat Domains Act as Sialic Acid-binding Lectins during Host Cell Invasion by Apicomplexan Parasites
- (2009) Nikolas Friedrich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Toxoplasma Profilin Is Essential for Host Cell Invasion and TLR11-Dependent Induction of an Interleukin-12 Response
- (2008) Fabienne Plattner et al. Cell Host & Microbe
- Toll-like receptors and their role in host resistance to Toxoplasma gondii
- (2008) Felix Yarovinsky IMMUNOLOGY LETTERS
- Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies
- (2008) Kristina E.M. Persson et al. JOURNAL OF CLINICAL INVESTIGATION
- MARveling at parasite invasion
- (2008) Kristin M. Hager et al. TRENDS IN PARASITOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now