Illuminating the membrane contact sites between the endoplasmic reticulum and the trans ‐Golgi network

The activity of Sac1 across ER–TGN contact sites requires the four-phosphate-adaptor-protein-1

(2019) Rossella Venditti et al.   JOURNAL OF CELL BIOLOGY

Molecular determinants of ER–Golgi contacts identified through a new FRET–FLIM system

(2019) Rossella Venditti et al.   JOURNAL OF CELL BIOLOGY

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ

(2019) Delphine Judith et al.   JOURNAL OF CELL BIOLOGY

Structure, functions and regulation of CERT, a lipid‐transfer protein for the delivery of ceramide at the ER–Golgi membrane contact sites

(2019) Keigo Kumagai et al.   FEBS LETTERS

The Oxysterol-Binding Protein Cycle: Burning Off PI(4)P to Transport Cholesterol

(2018) Bruno Antonny et al.   Annual Review of Biochemistry

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

(2018) Nikit Kumar et al.   JOURNAL OF CELL BIOLOGY

Lipid transport by TMEM24 at ER–plasma membrane contacts regulates pulsatile insulin secretion

(2017) Joshua A. Lees et al.   SCIENCE

ER-mitochondria tethering by PDZD8 regulates Ca2+dynamics in mammalian neurons

(2017) Yusuke Hirabayashi et al.   SCIENCE

Molecular mechanisms of STIM/Orai communication

(2016) Isabella Derler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

VAP, a Versatile Access Point for the Endoplasmic Reticulum: Review and analysis of FFAT-like motifs in the VAPome

(2016) Sarah E. Murphy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P

(2016) Rui Dong et al.   CELL

A Tether Is a Tether Is a Tether: Tethering at Membrane Contact Sites

(2016) Michal Eisenberg-Bord et al.   DEVELOPMENTAL CELL

Dynamic formation of ER–PM junctions presents a lipid phosphatase to regulate phosphoinositides

(2016) Eamonn J. Dickson et al.   JOURNAL OF CELL BIOLOGY

An inducible ER–Golgi tether facilitates ceramide transport to alleviate lipotoxicity

(2016) Li-Ka Liu et al.   JOURNAL OF CELL BIOLOGY

Critical Role of Intracellular RyR1 Calcium Release Channels in Skeletal Muscle Function and Disease

(2016) Erick O. Hernández-Ochoa et al.   Frontiers in Physiology

Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion

(2015) Tim Eiseler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CARTS biogenesis requires VAP–lipid transfer protein complexes functioning at the endoplasmic reticulum–Golgi interface

(2015) Yuichi Wakana et al.   MOLECULAR BIOLOGY OF THE CELL

Repeated ER–endosome contacts promote endosome translocation and neurite outgrowth

(2015) Camilla Raiborg et al.   NATURE

Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate

(2015) J. Moser von Filseck et al.   SCIENCE

PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts

(2015) J. Chung et al.   SCIENCE

A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes

(2015) Joachim Moser von Filseck et al.   Nature Communications

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

(2015) Alberto T Gatta et al.   eLife

Mature VLDL triggers the biogenesis of a distinct vesicle from thetrans-Golgi network for its export to the plasma membrane

(2014) Tanvir Hossain et al.   BIOCHEMICAL JOURNAL

ER Contact Sites Define the Position and Timing of Endosome Fission

(2014) Ashley A. Rowland et al.   CELL

Golgi compartmentation and identity

(2014) Effrosyni Papanikou et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphoregulation of the Ceramide Transport Protein CERT at Serine 315 in the Interaction with VAMP-associated Protein (VAP) for Inter-organelle Trafficking of Ceramide in Mammalian Cells

(2014) Keigo Kumagai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sac1–Vps74 structure reveals a mechanism to terminate phosphoinositide signaling in the Golgi apparatus

(2014) Yiying Cai et al.   JOURNAL OF CELL BIOLOGY

Cofilin recruits F-actin to SPCA1 and promotes Ca2+-mediated secretory cargo sorting

(2014) Christine Kienzle et al.   JOURNAL OF CELL BIOLOGY

Contact of cis-Golgi with ER exit sites executes cargo capture and delivery from the ER

(2014) Kazuo Kurokawa et al.   Nature Communications

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

(2014) Radu Stoica et al.   Nature Communications

Phosphatidylinositol-4-phosphate: The Golgi and beyond

(2013) Maria A. De Matteis et al.   BIOESSAYS

A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP

(2013) Bruno Mesmin et al.   CELL

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

Recruitment of arfaptins to the trans-Golgi network by PI(4)P and their involvement in cargo export

(2013) David Cruz-Garcia et al.   EMBO JOURNAL

Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins

(2013) Kenji Maeda et al.   NATURE

Oxysterol-binding proteins: Sterol and phosphoinositide sensors coordinating transport, signaling and metabolism

(2013) Vesa M. Olkkonen et al.   PROGRESS IN LIPID RESEARCH

Feedback Regulation of Receptor-Induced Ca2+ Signaling Mediated by E-Syt1 and Nir2 at Endoplasmic Reticulum-Plasma Membrane Junctions

(2013) Chi-Lun Chang et al.   Cell Reports

ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion

(2012) Eija Nissilä et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Connecting vesicular transport with lipid synthesis: FAPP2

(2012) Giovanni D'Angelo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The BAR Domain Protein Arfaptin-1 Controls Secretory Granule Biogenesis at the trans-Golgi Network

(2012) Helmuth Gehart et al.   DEVELOPMENTAL CELL

Cab45 is required for Ca2+-dependent secretory cargo sorting at the trans-Golgi network

(2012) Julia von Blume et al.   JOURNAL OF CELL BIOLOGY

A 14-3-3γ dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIIIβ to regulate post-Golgi carrier formation

(2012) Carmen Valente et al.   NATURE CELL BIOLOGY

Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites

(2011) Christopher J. Stefan et al.   CELL

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

(2011) Gregory D. Fairn et al.   JOURNAL OF CELL BIOLOGY

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

The Yeast Golgi Apparatus

(2011) Yasuyuki Suda et al.   TRAFFIC

The Distribution and Function of Phosphatidylserine in Cellular Membranes

(2010) Peter A. Leventis et al.   Annual Review of Biophysics

Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function

(2010) Andrew Manford et al.   EMBO JOURNAL

Variation in OSBPL10 is associated with dyslipidemia

(2010) Hiroshi Koriyama et al.   HYPERTENSION RESEARCH

Regulation of Oxysterol-binding Protein Golgi Localization through Protein Kinase D–mediated Phosphorylation

(2010) Sokha Nhek et al.   MOLECULAR BIOLOGY OF THE CELL

Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling

(2010) Z. Szentpetery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+ transfer from the ER to mitochondria: When, how and why

(2009) Rosario Rizzuto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

GOLPH3 Bridges Phosphatidylinositol-4- Phosphate and Actomyosin to Stretch and Shape the Golgi to Promote Budding

(2009) Holly C. Dippold et al.   CELL

The Golgi apparatus: Lessons from Drosophila

(2009) Vangelis Kondylis et al.   FEBS LETTERS

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Gluedand late endosome positioning

(2009) Nuno Rocha et al.   JOURNAL OF CELL BIOLOGY

OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism

(2009) Julia Perttilä et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Oxysterol Binding Protein–related Protein 9 (ORP9) Is a Cholesterol Transfer Protein That Regulates Golgi Structure and Function

(2009) Mike Ngo et al.   MOLECULAR BIOLOGY OF THE CELL

Grab a Golgi: Laser Trapping of Golgi Bodies Revealsin vivoInteractions with the Endoplasmic Reticulum

(2009) Imogen A. Sparkes et al.   TRAFFIC

Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1

(2008) Anastasia Blagoveshchenskaya et al.   JOURNAL OF CELL BIOLOGY

Coordinated Lipid Transfer between the Endoplasmic Reticulum and the Golgi Complex Requires the VAP Proteins and Is Essential for Golgi-mediated Transport

(2008) Diego Peretti et al.   MOLECULAR BIOLOGY OF THE CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

The Plant ER-Golgi Interface

(2008) Chris Hawes et al.   TRAFFIC