Dynamic formation of ER–PM junctions presents a lipid phosphatase to regulate phosphoinositides

Phosphoinositides regulate ion channels

(2015) Bertil Hille et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phosphatidylinositol-Phosphatidic Acid Exchange by Nir2 at ER-PM Contact Sites Maintains Phosphoinositide Signaling Competence

(2015) Yeun Ju Kim et al.   DEVELOPMENTAL CELL

Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering

(2015) O. Idevall-Hagren et al.   EMBO JOURNAL

Three-dimensional architecture of extended synaptotagmin-mediated endoplasmic reticulum–plasma membrane contact sites

(2015) Rubén Fernández-Busnadiego et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts

(2015) J. Chung et al.   SCIENCE

Recurrent turnover of senescent cells during regeneration of a complex structure

(2015) Maximina H Yun et al.   eLife

Sac1–Vps74 structure reveals a mechanism to terminate phosphoinositide signaling in the Golgi apparatus

(2014) Yiying Cai et al.   JOURNAL OF CELL BIOLOGY

Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics

(2014) William A. Prinz   JOURNAL OF CELL BIOLOGY

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

(2014) Gerald R.V. Hammond et al.   JOURNAL OF CELL BIOLOGY

Nerve Growth Factor Sensitizes Adult Sympathetic Neurons to the Proinflammatory Peptide Bradykinin

(2014) O. Vivas et al.   JOURNAL OF NEUROSCIENCE

Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer

(2014) Curtis M. Schauder et al.   NATURE

A polarized Ca2+, diacylglycerol and STIM1 signalling system regulates directed cell migration

(2014) Feng-Chiao Tsai et al.   NATURE CELL BIOLOGY

Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current

(2014) E. J. Dickson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Four-Step Cycle Driven by PI(4)P Hydrolysis Directs Sterol/PI(4)P Exchange by the ER-Golgi Tether OSBP

(2013) Bruno Mesmin et al.   CELL

PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

(2013) Francesca Giordano et al.   CELL

ER–PM connections: sites of information transfer and inter-organelle communication

(2013) Christopher J Stefan et al.   CURRENT OPINION IN CELL BIOLOGY

Quantitative properties and receptor reserve of the DAG and PKC branch of Gq-coupled receptor signaling

(2013) Björn H. Falkenburger et al.   JOURNAL OF GENERAL PHYSIOLOGY

Quantitative properties and receptor reserve of the IP3and calcium branch of Gq-coupled receptor signaling

(2013) Eamonn J. Dickson et al.   JOURNAL OF GENERAL PHYSIOLOGY

Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

(2013) Tamas Balla   PHYSIOLOGICAL REVIEWS

Resolution Doubling in 3D-STORM Imaging through Improved Buffers

(2013) Nicolas Olivier et al.   PLoS One

Feedback Regulation of Receptor-Induced Ca2+ Signaling Mediated by E-Syt1 and Nir2 at Endoplasmic Reticulum-Plasma Membrane Junctions

(2013) Chi-Lun Chang et al.   Cell Reports

Allosteric Activation of the Phosphoinositide Phosphatase Sac1 by Anionic Phospholipids

(2012) Shurong Zhong et al.   BIOCHEMISTRY

ER-to-Plasma Membrane Tethering Proteins Regulate Cell Signaling and ER Morphology

(2012) Andrew G. Manford et al.   DEVELOPMENTAL CELL

ER-shaping proteins facilitate lipid exchange between the ER and mitochondria in S. cerevisiae

(2012) C. Voss et al.   JOURNAL OF CELL SCIENCE

A conserved membrane-binding domain targets proteins to organelle contact sites

(2012) A. Toulmay et al.   JOURNAL OF CELL SCIENCE

Orai-STIM-mediated Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe

(2012) E. J. Dickson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes

(2012) S.-H. Shim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Dynamics and Apoptosis--the ER Connection

(2012) S. Hoppins et al.   SCIENCE

Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites

(2011) Christopher J. Stefan et al.   CELL

Lipid transfer and signaling at organelle contact sites: the tip of the iceberg

(2011) Alexandre Toulmay et al.   CURRENT OPINION IN CELL BIOLOGY

Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry

(2011) Jonathan Clark et al.   NATURE METHODS

Evaluation of fluorophores for optimal performance in localization-based super-resolution imaging

(2011) Graham T Dempsey et al.   NATURE METHODS

Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes

(2011) Y. Uchida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Triggering Actin Comets Versus Membrane Ruffles: Distinctive Effects of Phosphoinositides on Actin Reorganization

(2011) T. Ueno et al.   Science Signaling

Lipid Trafficking sans Vesicles: Where, Why, How?

(2010) William A. Prinz   CELL

Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function

(2010) Andrew Manford et al.   EMBO JOURNAL

Kinetics of PIP2metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells

(2010) Björn H. Falkenburger et al.   JOURNAL OF GENERAL PHYSIOLOGY

Organelle-specific, rapid induction of molecular activities and membrane tethering

(2010) Toru Komatsu et al.   NATURE METHODS

Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling

(2010) Z. Szentpetery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

Dependence of STIM1/Orai1-mediated Calcium Entry on Plasma Membrane Phosphoinositides

(2009) Marek K. Korzeniowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1

(2008) Anastasia Blagoveshchenskaya et al.   JOURNAL OF CELL BIOLOGY

Functional stoichiometry of the unitary calcium-release-activated calcium channel

(2008) W. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA