The annexin A1/FPR2 signaling axis expands alveolar macrophages, limits viral replication, and attenuates pathogenesis in the murine influenza A virus infection model

Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes

(2018) Nicole Heitzig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The Annexin A1 Receptor FPR2 Regulates the Endosomal Export of Influenza Virus

(2018) Fryad Rahman et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Annexins in Translational Research: Hidden Treasures to Be Found

(2018) Sebastian Schloer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deficiency in Fpr2 results in reduced number of Lin-c-Kit+Sca1+myeloid progenitor cells

(2018) Keqiang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Annexin A1 in plasma from patients with bronchial asthma: its association with lung function

(2018) Sun-Hye Lee et al.   BMC Pulmonary Medicine

Alveolar Macrophages in the Resolution of Inflammation, Tissue Repair, and Tolerance to Infection

(2018) Benoit Allard et al.   Frontiers in Immunology

ISGylation – a key to lock the cell gates for preventing the spread of threats

(2017) Carolina Villarroya-Beltri et al.   JOURNAL OF CELL SCIENCE

Influenza virus replication in macrophages: balancing protection and pathogenesis

(2017) Troy D. Cline et al.   JOURNAL OF GENERAL VIROLOGY

AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality

(2017) Hongbo Zhang et al.   JOURNAL OF IMMUNOLOGY

The Formyl Peptide Receptors: Diversity of Ligands and Mechanism for Recognition

(2017) Hui-Qiong He et al.   MOLECULES

Host-directed therapies for bacterial and viral infections

(2017) Stefan H. E. Kaufmann et al.   NATURE REVIEWS DRUG DISCOVERY

Alveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial Cells

(2017) Amber Cardani et al.   PLoS Pathogens

FPR2: A Novel Promising Target for the Treatment of Influenza

(2017) Marie-Christine Alessi et al.   Frontiers in Microbiology

Inhibition of Phosphodiesterase-4 during Pneumococcal Pneumonia Reduces Inflammation and Lung Injury in Mice

(2016) Luciana P. Tavares et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Influenza virus damages the alveolar barrier by disrupting epithelial cell tight junctions

(2016) Kirsty R. Short et al.   EUROPEAN RESPIRATORY JOURNAL

Formyl Peptide Receptor 2 Plays a Deleterious Role During Influenza A Virus Infections

(2016) Sergey Tcherniuk et al.   JOURNAL OF INFECTIOUS DISEASES

Hierarchical effects of pro-inflammatory cytokines on the post-influenza susceptibility to pneumococcal coinfection

(2016) Stefanie Duvigneau et al.   Scientific Reports

Annexin A1 mimetic peptide controls the inflammatory and fibrotic effects of silica particles in mice

(2015) P G Trentin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lethal influenza infection: Is a macrophage to blame?

(2015) E. Scott Halstead et al.   Expert Review of Anti-Infective Therapy

Targeting formyl peptide receptor 2 reduces leukocyte-endothelial interactions in a murine model of stroke

(2015) Helen K. Smith et al.   FASEB JOURNAL

Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2

(2015) Stefan A. Schattgen et al.   JOURNAL OF IMMUNOLOGY

Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

(2015) Jesmond Dalli et al.   NATURE MEDICINE

An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation

(2015) Jason E. Shoemaker et al.   PLoS Pathogens

Delivery of GM-CSF to Protect against Influenza Pneumonia

(2015) Renuka Subramaniam et al.   PLoS One

Annexin1 regulates DC efferocytosis and cross-presentation during Mycobacterium tuberculosis infection

(2014) Fanny Tzelepis et al.   JOURNAL OF CLINICAL INVESTIGATION

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis

(2014) C. Happle et al.   Science Translational Medicine

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

(2014) Christoph Schneider et al.   PLoS Pathogens

Influenza virus and endothelial cells: a species specific relationship

(2014) Kirsty R. Short et al.   Frontiers in Microbiology

Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung

(2013) Alexander V. Misharin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

(2013) Masayuki Morita et al.   CELL

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Structural Determinants for the Interaction of Formyl Peptide Receptor 2 with Peptide Ligands

(2013) Hui-Qiong He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

(2013) H. E. Ghoneim et al.   JOURNAL OF IMMUNOLOGY

Annexin A6-Balanced Late Endosomal Cholesterol Controls Influenza A Replication and Propagation

(2013) A. Musiol et al.   mBio

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

(2012) Julie Helft et al.   JOURNAL OF CLINICAL INVESTIGATION

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

(2012) Fatimah S Dawood et al.   LANCET INFECTIOUS DISEASES

Colony stimulating factors and myeloid cell biology in health and disease

(2012) John A. Hamilton et al.   TRENDS IN IMMUNOLOGY

Annexin A1 and the regulation of innate and adaptive immunity

(2012) Felicity N. E. Gavins et al.   Frontiers in Immunology

Activation of the Annexin A1 Pathway Underlies the Protective Effects Exerted by Estrogen in Polymorphonuclear Leukocytes

(2011) Suchita Nadkarni et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis

(2011) Amílcar S Damazo et al.   BMC IMMUNOLOGY

Depletion of alveolar macrophages prolongs survival in response to acute pneumovirus infection

(2011) Peter Rigaux et al.   VIROLOGY

Human Formyl Peptide Receptor 2 Senses Highly Pathogenic Staphylococcus aureus

(2010) Dorothee Kretschmer et al.   Cell Host & Microbe

Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signalling

(2010) Danute Pupjalis et al.   EMBO Molecular Medicine

Cutting Edge: A Critical Role for the G Protein-Coupled Receptor mFPR2 in Airway Inflammation and Immune Responses

(2010) K. Chen et al.   JOURNAL OF IMMUNOLOGY

Protection of Mice against Lethal Challenge with 2009 H1N1 Influenza A Virus by 1918-Like and Classical Swine H1N1 Based Vaccines

(2010) Balaji Manicassamy et al.   PLoS Pathogens

The Pathology of Influenza Virus Infections

(2008) Jeffery K. Taubenberger et al.   Annual Review of Pathology-Mechanisms of Disease

Pathology of human influenza revisited

(2008) Thijs Kuiken et al.   VACCINE

Cellular Proteins in Influenza Virus Particles

(2008) Megan L. Shaw et al.   PLoS Pathogens

Impaired phagocytic mechanism in annexin 1 null macrophages

(2006) Simon Yona et al.   BRITISH JOURNAL OF PHARMACOLOGY