An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation

CCR2+ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality

(2014) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Pathogenic Influenza Viruses and Coronaviruses Utilize Similar and Contrasting Approaches To Control Interferon-Stimulated Gene Responses

(2014) V. D. Menachery et al.   mBio

Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice

(2013) Nicolas Tchitchek et al.   BMC Systems Biology

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

SUMOylation Affects the Interferon Blocking Activity of the Influenza A Nonstructural Protein NS1 without Affecting Its Stability or Cellular Localization

(2013) A. Santos et al.   JOURNAL OF VIROLOGY

Regulation of Toll-like receptor signaling pathways in innate immune responses

(2012) Cheng Qian et al.   Annals of the New York Academy of Sciences

CTen: a web-based platform for identifying enriched cell types from heterogeneous microarray data

(2012) Jason E Shoemaker et al.   BMC GENOMICS

Integrated network analysis reveals a novel role for the cell cycle in 2009 pandemic influenza virus-induced inflammation in macaque lungs

(2012) Jason E Shoemaker et al.   BMC Systems Biology

Integrated Clinical, Pathologic, Virologic, and Transcriptomic Analysis of H5N1 Influenza Virus-Induced Viral Pneumonia in the Rhesus Macaque

(2012) K. Shinya et al.   JOURNAL OF VIROLOGY

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Ultrasensitivity and Positive Feedback to Promote Sharp Mitotic Entry

(2011) Youlian Goulev et al.   MOLECULAR CELL

Ultrasensitivity in the Regulation of Cdc25C by Cdk1

(2011) Nicole B. Trunnell et al.   MOLECULAR CELL

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

The ability of pandemic influenza virus hemagglutinins to induce lower respiratory pathology is associated with decreased surfactant protein D binding

(2011) Li Qi et al.   VIROLOGY

Toll-like receptor pre-stimulation protects mice against lethal infection with highly pathogenic influenza viruses

(2011) Kyoko Shinya et al.   Virology Journal

SnapShot: Pathways of Antiviral Innate Immunity

(2010) Lijun Sun et al.   CELL

Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection

(2010) C. Cilloniz et al.   JOURNAL OF VIROLOGY

Extracellular 2'-5' Oligoadenylate Synthetase Stimulates RNase L-Independent Antiviral Activity: a Novel Mechanism of Virus-Induced Innate Immunity

(2010) H. Kristiansen et al.   JOURNAL OF VIROLOGY

MyD88 Signaling Is Indispensable for Primary Influenza A Virus Infection but Dispensable for Secondary Infection

(2010) S.-U. Seo et al.   JOURNAL OF VIROLOGY

Modification of Nonstructural Protein 1 of Influenza A Virus by SUMO1

(2010) K. Xu et al.   JOURNAL OF VIROLOGY

ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems

(2010) V. Kaimal et al.   NUCLEIC ACIDS RESEARCH

Viral Replication Rate Regulates Clinical Outcome and CD8 T Cell Responses during Highly Pathogenic H5N1 Influenza Virus Infection in Mice

(2010) Yasuko Hatta et al.   PLoS Pathogens

H5N1 influenza viruses: outbreaks and biological properties

(2009) Gabriele Neumann et al.   CELL RESEARCH

Identification of the non-structural influenza A viral protein NS1A as a bona fide target of the Small Ubiquitin-like MOdifier by the use of dicistronic expression constructs

(2009) Sangita Pal et al.   JOURNAL OF VIROLOGICAL METHODS

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Lethal Influenza Virus Infection in Macaques Is Associated with Early Dysregulation of Inflammatory Related Genes

(2009) Cristian Cillóniz et al.   PLoS Pathogens

Simultaneous Inference in General Parametric Models

(2008) Torsten Hothorn et al.   BIOMETRICAL JOURNAL

Identifying Fragilities in Biochemical Networks: Robust Performance Analysis of Fas Signaling-Induced Apoptosis

(2008) Jason E. Shoemaker et al.   BIOPHYSICAL JOURNAL

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS