Lethal influenza infection: Is a macrophage to blame?

Alternative activation of macrophages and pulmonary fibrosis are modulated by scavenger receptor, macrophage receptor with collagenous structure

(2015) Shubha Murthy et al.   FASEB JOURNAL

Protection from Severe Influenza Virus Infections in Mice Carrying theMx1Influenza Virus Resistance Gene Strongly Depends on Genetic Background

(2015) Dai-Lun Shin et al.   JOURNAL OF VIROLOGY

A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza

(2015) Wenji Piao et al.   Cell Reports

An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation

(2015) Jason E. Shoemaker et al.   PLoS Pathogens

SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation

(2015) Linlin Yang et al.   PLoS One

Delivery of GM-CSF to Protect against Influenza Pneumonia

(2015) Renuka Subramaniam et al.   PLoS One

Influenza virus replication in lung epithelial cells depends on redox-sensitive pathways activated by NOX4-derived ROS

(2014) Donatella Amatore et al.   CELLULAR MICROBIOLOGY

Transient ablation of alveolar macrophages leads to massive pathology of influenza infection without affecting cellular adaptive immunity

(2014) Christina Purnama et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Influenza A virus and TLR7 activation potentiate NOX2 oxidase-dependent ROS production in macrophages

(2014) E. E. To et al.   FREE RADICAL RESEARCH

Targeted Prostaglandin E2 Inhibition Enhances Antiviral Immunity through Induction of Type I Interferon and Apoptosis in Macrophages

(2014) François Coulombe et al.   IMMUNITY

PI3K/Akt Signaling Pathway Modulates Influenza Virus Induced Mouse Alveolar Macrophage Polarization to M1/M2b

(2014) Xiangfeng Zhao et al.   PLoS One

NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein

(2014) J. Jaworska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

(2014) Christoph Schneider et al.   PLoS Pathogens

Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function

(2013) Atsushi Nakamura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

(2013) H. E. Ghoneim et al.   JOURNAL OF IMMUNOLOGY

The severe pathogenicity of alveolar macrophage-depleted ferrets infected with 2009 pandemic H1N1 influenza virus

(2013) Heui Man Kim et al.   VIROLOGY

Glutathione Peroxidase-1 Reduces Influenza A Virus–Induced Lung Inflammation

(2012) Selcuk Yatmaz et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Distinct Macrophage Subpopulations Characterize Acute Infection and Chronic Inflammatory Lung Disease

(2012) M. Duan et al.   JOURNAL OF IMMUNOLOGY

GM-CSF Priming Drives Bone Marrow-Derived Macrophages to a Pro-Inflammatory Pattern and Downmodulates PGE2 in Response to TLR2 Ligands

(2012) Carlos Arterio Sorgi et al.   PLoS One

Fas Determines Differential Fates of Resident and Recruited Macrophages during Resolution of Acute Lung Injury

(2011) William J Janssen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

GM-CSF in the Lung Protects against Lethal Influenza Infection

(2011) Fang-Fang Huang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MARCO Regulates Early Inflammatory Responses against Influenza

(2011) Sanjukta Ghosh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

GM-CSF modulates pulmonary resistance to influenza A infection

(2011) Zvjezdana Sever-Chroneos et al.   ANTIVIRAL RESEARCH

Temporal Dynamics of Host Molecular Responses Differentiate Symptomatic and Asymptomatic Influenza A Infection

(2011) Yongsheng Huang et al.   PLoS Genetics

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

(2011) Ross Vlahos et al.   PLoS Pathogens

Protective effects of recombinant human granulocyte macrophage colony stimulating factor on H1N1 influenza virus-induced pneumonia in mice

(2010) Hai Huang et al.   CYTOKINE

Pulmonary Surfactant: An Immunological Perspective

(2009) Zissis Chroneos et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Alveolar Macrophages Are Indispensable for Controlling Influenza Viruses in Lungs of Pigs

(2008) H. M. Kim et al.   JOURNAL OF VIROLOGY