Aconitine induces cardiomyocyte damage by mitigating BNIP3‐dependent mitophagy and the TNFα‐NLRP3 signalling axis

Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy

(2019) Dan Hao et al.   Cell Death & Disease

Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial‐lysosomal crosstalk

(2019) Jiyao Sheng et al.   CELL PROLIFERATION

Lipid-modified cell-penetrating peptide-based self-assembly micelles for co-delivery of narciclasine and siULK1 in hepatocellular carcinoma therapy

(2018) Xiaoyun Wang et al.   Acta Biomaterialia

Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy

(2018) Fengbo Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Synthesis of deuterium-labelled analogues of NLRP3 inflammasome inhibitor MCC950

(2018) Manohar Salla et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Asymmetric synthesis of tetrahydroisoquinoline-fused spirooxindoles as Ras-GTP inhibitors that inhibit colon adenocarcinoma cell proliferation and invasion

(2018) Qian Zhao et al.   CHEMICAL COMMUNICATIONS

Isolation, Synthesis, and Semisynthesis of Amaryllidaceae Constituents from Narcissus and Galanthus sp.: De Novo Total Synthesis of 2-epi-Narciclasine

(2018) Suresh Borra et al.   JOURNAL OF NATURAL PRODUCTS

Inhibition of excessive autophagy and mitophagy mediates neuroprotective effects of URB597 against chronic cerebral hypoperfusion

(2018) Shao-Hua Su et al.   Cell Death & Disease

Discovery of a self-assembling and self-adjuvant lipopeptide as a saccharide-free peptide vaccine targeting EGFRvIII positive cutaneous melanoma

(2018) Yujuan Chen et al.   Biomaterials Science

Narciclasine induces autophagy-dependent apoptosis in triple-negative breast cancer cells by regulating the AMPK-ULK1 axis

(2018) Chuan Cao et al.   CELL PROLIFERATION

Therapeutic strategies involving survivin inhibition in cancer

(2018) David Martínez‐García et al.   MEDICINAL RESEARCH REVIEWS

Dynamic genome and transcriptional network-based biomarkers and drugs: precision in breast cancer therapy

(2018) Ioannis D. Kyrochristos et al.   MEDICINAL RESEARCH REVIEWS

Mitochondrial dysfunction and potential anticancer therapy

(2017) Matilde E. Lleonart et al.   MEDICINAL RESEARCH REVIEWS

Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction

(2017) Yi Zhang et al.   Cell Death & Disease

Administration of follicle-stimulating hormone induces autophagy via upregulation of HIF-1α in mouse granulosa cells

(2017) Jilong Zhou et al.   Cell Death & Disease

Cytotoxicity of Aconitum alkaloid and its interaction with calf thymus DNA by multi-spectroscopic techniques

(2017) Fei Liu et al.   Scientific Reports

Phagocytosis of environmental or metabolic crystalline particles induces cytotoxicity by triggering necroptosis across a broad range of particle size and shape

(2017) Mohsen Honarpisheh et al.   Scientific Reports

Regulated necrosis-related molecule mRNA expression in humans and mice and in murine acute tissue injury and systemic autoimmunity leading to progressive organ damage, and progressive fibrosis

(2016) M. Honarpisheh et al.   BIOSCIENCE REPORTS

Antitoxic effect of Veratrilla baillonii on the acute toxicity in mice induced by Aconitum brachypodum , one of the genus Aconitum

(2016) Yue-Bin Ge et al.   JOURNAL OF ETHNOPHARMACOLOGY

Targeting Programmed Cell Death Using Small-Molecule Compounds to Improve Potential Cancer Therapy

(2016) Bowen Ke et al.   MEDICINAL RESEARCH REVIEWS

Involvement of PI3K, MAPK ERK1/2 and p38 in Functional Stimulation of Mesenchymal Progenitor Cells by Alkaloid Songorine

(2015) G. N. Zyuz’kov et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Development of a Recombinant Xenogeneic Tumor Necrosis Factor Alpha Protein Vaccine To Protect Mice from Experimental Colitis

(2015) Yang Wan et al.   Clinical and Vaccine Immunology

BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory

(2015) Timothy E. O’Sullivan et al.   IMMUNITY

A review on phytochemistry and pharmacological activities of the processed lateral root of Aconitum carmichaelii Debeaux

(2015) Guohong Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

A review on phytochemistry, pharmacology and toxicology studies ofAconitum

(2014) Eric Nyirimigabo et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Effective inhibition of melanoma tumorigenesis and growth via a new complex vaccine based on NY-ESO-1-alum-polysaccharide-HH2

(2014) Meng Li et al.   Molecular Cancer

Aconitine-induced Ca2+ overload causes arrhythmia and triggers apoptosis through p38 MAPK signaling pathway in rats

(2014) Gui-bo Sun et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitophagy: mechanisms, pathophysiological roles, and analysis

(2012) Wen-Xing Ding et al.   BIOLOGICAL CHEMISTRY

Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy

(2012) Rita A. Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A gene ontology inferred from molecular networks

(2012) Janusz Dutkowski et al.   NATURE BIOTECHNOLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Pharmacokinetics of aconitine as the targeted marker of Fuzi (Aconitum carmichaeli) following single and multiple oral administrations of Fuzi extracts in rat by UPLC/MS/MS

(2011) Lan Tang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Semisynthesis and pharmacological investigation of lipo-alkaloids prepared from aconitine

(2010) Botond Borcsa et al.   FITOTERAPIA

Mechanism study of Aconitum-induced neurotoxicity in PC12 cells: Involvement of dopamine release and oxidative damage

(2010) Yinglan Zhao et al.   NEUROTOXICOLOGY

Role of BNIP3 and NIX in cell death, autophagy and mitophagy

(2009) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

Aconite poisoning

(2009) Thomas Y.K. Chan   CLINICAL TOXICOLOGY

Aconitum in Traditional Chinese Medicine—A valuable drug or an unpredictable risk?

(2009) Judith Singhuber et al.   JOURNAL OF ETHNOPHARMACOLOGY