Control of developmental networks by Rac/Rho small GTPases: How cytoskeletal changes during embryogenesis are orchestrated

Loss of Acetylcholine Signaling Reduces Cell Clearance Deficiencies in Caenorhabditis elegans

(2016) Sérgio M. Pinto et al.   PLoS One

GEFs and Rac GTPases control directional specificity of neurite extension along the anterior–posterior axis

(2016) Chaogu Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polarized Rac-dependent protrusions drive epithelial intercalation in the embryonic epidermis ofC. elegans

(2015) Elise Walck-Shannon et al.   DEVELOPMENT

Identifying Regulators of Morphogenesis Common to Vertebrate Neural Tube Closure and Caenorhabditis elegans Gastrulation

(2015) J. L. Sullivan-Brown et al.   GENETICS

The RhoGAP activity of CYK-4/MgcRacGAP functions non-canonically by promoting RhoA activation during cytokinesis

(2015) Donglei Zhang et al.   eLife

Role of SNTA1 in Rac1 activation, modulation of ROS generation and migratory potential of human breast cancer cells

(2014) H F Bhat et al.   BRITISH JOURNAL OF CANCER

Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans

(2014) L J Neukomm et al.   CELL DEATH AND DIFFERENTIATION

The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP

(2014) A. D. Norris et al.   DEVELOPMENT

PDR-1/hParkin negatively regulates the phagocytosis of apoptotic cell corpses in Caenorhabditis elegans

(2014) J Cabello et al.   Cell Death & Disease

Rac1 GTPase, a multifunctional player in the regulation of genotoxic stress response

(2013) Gerhard Fritz et al.   CELL CYCLE

Phagocytic receptor signaling regulates clathrin and epsin-mediated cytoskeletal remodeling during apoptotic cell engulfment in C. elegans

(2013) Q. Shen et al.   DEVELOPMENT

Role of Small GTPase Protein Rac1 in Cardiovascular Diseases

(2013) Nicola Ferri et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Emerging role of oxidative stress in metabolic syndrome and cardiovascular diseases: important role of Rac/NADPH oxidase

(2013) Mohammad T Elnakish et al.   JOURNAL OF PATHOLOGY

MT1-MMP modulates melanoma cell dissemination and metastasis through activation of MMP2 and RAC1

(2013) Khvaramze Shaverdashvili et al.   Pigment Cell & Melanoma Research

A Rac1/Cdc42 GTPase-Specific Small Molecule Inhibitor Suppresses Growth of Primary Human Prostate Cancer Xenografts and Prolongs Survival in Mice

(2013) Karin Zins et al.   PLoS One

PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1

(2013) H. Ebi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple functions of the noncanonical Wnt pathway

(2013) Eva Gómez-Orte et al.   TRENDS IN GENETICS

A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease

(2013) Donald E. Spratt et al.   Nature Communications

CED-1, CED-7, and TTR-52 Regulate Surface Phosphatidylserine Expression on Apoptotic and Phagocytic Cells

(2012) James Mapes et al.   CURRENT BIOLOGY

The RhoGAP Domain of CYK-4 Has an Essential Role in RhoA Activation

(2012) Andy Loria et al.   CURRENT BIOLOGY

Centralspindlin: At the heart of cytokinesis

(2012) Erin A. White et al.   Cytoskeleton

RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4

(2012) Yu Chung Tse et al.   MOLECULAR BIOLOGY OF THE CELL

The Rac GTP Exchange Factor TIAM-1 Acts with CDC-42 and the Guidance Receptor UNC-40/DCC in Neuronal Protrusion and Axon Guidance

(2012) Rafael S. Demarco et al.   PLoS Genetics

SLI-1 Cbl Inhibits the Engulfment of Apoptotic Cells in C. elegans through a Ligase-Independent Function

(2012) Courtney Anderson et al.   PLoS Genetics

UNC-40/DCC, SAX-3/Robo, and VAB-1/Eph Polarize F-Actin during Embryonic Morphogenesis by Regulating the WAVE/SCAR Actin Nucleation Complex

(2012) Yelena Y. Bernadskaya et al.   PLoS Genetics

Integrin α PAT-2/CDC-42 Signaling Is Required for Muscle-Mediated Clearance of Apoptotic Cells in Caenorhabditis elegans

(2012) Hsiao-Han Hsieh et al.   PLoS Genetics

Proper regulation of Cdc42 activity is required for tight actin concentration at the equator during cytokinesis in adherent mammalian Cells

(2011) Xiaodong Zhu et al.   EXPERIMENTAL CELL RESEARCH

The 'invisible hand': regulation of RHO GTPases by RHOGDIs

(2011) Rafael Garcia-Mata et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells

(2011) A. W. Kao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engulfment of Apoptotic Cells in C. elegans Is Mediated by Integrin α/SRC Signaling

(2010) Tsung-Yuan Hsu et al.   CURRENT BIOLOGY

ccz-1 mediates the digestion of apoptotic corpses in C. elegans

(2010) C. Nieto et al.   JOURNAL OF CELL SCIENCE

Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells

(2010) Jason M. Kinchen et al.   NATURE

Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans

(2010) Lukas J. Neukomm et al.   NATURE CELL BIOLOGY

Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor

(2010) Xiaochen Wang et al.   NATURE CELL BIOLOGY

The Wnt Pathway Controls Cell Death Engulfment, Spindle Orientation, and Migration through CED-10/Rac

(2010) Juan Cabello et al.   PLOS BIOLOGY

Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans

(2009) Michael E Hurwitz et al.   PLOS BIOLOGY

Caenorhabditis elegans Myotubularin MTM-1 Negatively Regulates the Engulfment of Apoptotic Cells

(2009) Wei Zou et al.   PLoS Genetics

The WAVE/SCAR complex promotes polarized cell movements and actin enrichment in epithelia during C. elegans embryogenesis

(2008) Falshruti B. Patel et al.   DEVELOPMENTAL BIOLOGY

The Arp2/3 Activators WAVE and WASP Have Distinct Genetic Interactions With Rac GTPases in Caenorhabditis elegans Axon Guidance

(2008) M. A. Shakir et al.   GENETICS

Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis

(2008) J. C. Canman et al.   SCIENCE