MT1-MMP modulates melanoma cell dissemination and metastasis through activation of MMP2 and RAC1

Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1α-induced invasion of human esophageal carcinoma cells

(2012) Meng-Liang Lin et al.   MOLECULAR CARCINOGENESIS

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

(2012) Michael Krauthammer et al.   NATURE GENETICS

A Notch1–neuregulin1 autocrine signaling loop contributes to melanoma growth

(2012) K Zhang et al.   ONCOGENE

Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes

(2011) Kenneth L. Scott et al.   CANCER CELL

Deletion of PTENP1 Pseudogene in Human Melanoma

(2011) Laura Poliseno et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hypoxia–reoxygenation increase invasiveness of PANC-1 cells through Rac1/MMP-2

(2010) Marcelo G. Binker et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MT1-MMP Is Required for Myeloid Cell Fusion via Regulation of Rac1 Signaling

(2010) Pilar Gonzalo et al.   DEVELOPMENTAL CELL

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Chemokine Receptor CXCR4 and the Metalloproteinase MT1-MMP Are Mutually Required during Melanoma Metastasis to Lungs

(2009) Rubén A. Bartolomé et al.   AMERICAN JOURNAL OF PATHOLOGY

Vascular regression and survival are differentially regulated by MT1-MMP and TIMPs in the aortic ring model of angiogenesis

(2009) A. C. Aplin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Chemical Genomic Approach Identifies Matrix Metalloproteinases as Playing an Essential and Specific Role in Xenopus Melanophore Migration

(2009) Matthew L. Tomlinson et al.   CHEMISTRY & BIOLOGY

Cytoplasmic tail of MT1-MMP regulates macrophage motility independently from its protease activity

(2009) Takeharu Sakamoto et al.   GENES TO CELLS

Matrix metalloproteinase-2 is involved in the migration and network formation of enteric neural crest-derived cells

(2009) Richard B. Anderson   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

A Novel Protein Associated with Membrane-type 1 Matrix Metalloproteinase Binds p27kip1and Regulates RhoA Activation, Actin Remodeling, and Matrigel Invasion

(2009) Daisuke Hoshino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SecretedVersusMembrane-anchored Collagenases

(2009) Farideh Sabeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch1 is an effector of Akt and hypoxia in melanoma development

(2008) Barbara Bedogni et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Basis of Metastasis

(2008) Anne C. Chiang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Breaching the basement membrane: who, when and how?

(2008) R. Grant Rowe et al.   TRENDS IN CELL BIOLOGY