The RhoGAP activity of CYK-4/MgcRacGAP functions non-canonically by promoting RhoA activation during cytokinesis

Aurora B Kinase Promotes Cytokinesis by Inducing Centralspindlin Oligomers that Associate with the Plasma Membrane

(2015) Angika Basant et al.   DEVELOPMENTAL CELL

MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells

(2015) Elaina B. Breznau et al.   MOLECULAR BIOLOGY OF THE CELL

Oligonucleotide-based targeted gene editing in C. elegans via the CRISPR/Cas9 system

(2014) Pei Zhao et al.   CELL RESEARCH

Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4

(2014) Yang Zou et al.   FEBS LETTERS

A postmitotic function and distinct localization mechanism for centralspindlin at a stable intercellular bridge

(2013) Kang Zhou et al.   DEVELOPMENTAL BIOLOGY

A Conserved RhoGAP Limits M Phase Contractility and Coordinates with Microtubule Asters to Confine RhoA during Cytokinesis

(2013) Esther Zanin et al.   DEVELOPMENTAL CELL

Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination

(2013) Daniel J Dickinson et al.   NATURE METHODS

Identification of 526 Conserved Metazoan Genetic Innovations Exposes a New Role for Cofactor E-like in Neuronal Microtubule Homeostasis

(2013) Melissa Y. Frédéric et al.   PLoS Genetics

Cytokinesis in Animal Cells

(2012) Rebecca A. Green et al.   Annual Review of Cell and Developmental Biology

The RhoGAP Domain of CYK-4 Has an Essential Role in RhoA Activation

(2012) Andy Loria et al.   CURRENT BIOLOGY

Centralspindlin: At the heart of cytokinesis

(2012) Erin A. White et al.   Cytoskeleton

Morphogenesis and the Cell Cycle

(2012) Audrey S. Howell et al.   GENETICS

Activation of p115-RhoGEF Requires Direct Association of Gα13and the Dbl Homology Domain

(2012) Zhe Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CYK4 inhibits Rac1-dependent PAK1 and ARHGEF7 effector pathways during cytokinesis

(2012) Ricardo Nunes Bastos et al.   JOURNAL OF CELL BIOLOGY

RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4

(2012) Yu Chung Tse et al.   MOLECULAR BIOLOGY OF THE CELL

Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis

(2012) Sergey Lekomtsev et al.   NATURE

Improved Mos1-mediated transgenesis in C. elegans

(2012) Christian Frøkjær-Jensen et al.   NATURE METHODS

SLiCE: a novel bacterial cell extract-based DNA cloning method

(2012) Yongwei Zhang et al.   NUCLEIC ACIDS RESEARCH

Targeting of the RhoGEF Ect2 to the Equatorial Membrane Controls Cleavage Furrow Formation during Cytokinesis

(2011) Kuan-Chung Su et al.   DEVELOPMENTAL CELL

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

Aurora B and 14-3-3 Coordinately Regulate Clustering of Centralspindlin during Cytokinesis

(2010) Max E. Douglas et al.   CURRENT BIOLOGY

Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation

(2010) Zhe Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C. elegans Mutant Identification with a One-Step Whole-Genome-Sequencing and SNP Mapping Strategy

(2010) Maria Doitsidou et al.   PLoS One

Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells

(2009) Mark E. Burkard et al.   PLOS BIOLOGY

Polo-Like Kinase 1 Directs Assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF Complex to Initiate Cleavage Furrow Formation

(2009) Benjamin A. Wolfe et al.   PLOS BIOLOGY

Regulation of cytokinesis by Rho GTPase flux

(2008) Ann L. Miller et al.   NATURE CELL BIOLOGY

Single-copy insertion of transgenes in Caenorhabditis elegans

(2008) Christian Frøkjær-Jensen et al.   NATURE GENETICS

Membrane-dependent signal integration by the Ras activator Son of sevenless

(2008) Jodi Gureasko et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis

(2008) J. C. Canman et al.   SCIENCE