Silaboration of [1.1.1]Propellane: A Storable Feedstock for Bicyclo[1.1.1]pentane Derivatives

Deoxygenative Borylation of Secondary and Tertiary Alcohols

(2019) Florian Werner Friese et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aminoalkylation of [1.1.1]Propellane Enables Direct Access to High-Value 3-Alkylbicyclo[1.1.1]pentan-1-amines

(2019) Jonathan M. E. Hughes et al.   ORGANIC LETTERS

A General Route to Bicyclo[1.1.1]pentanes through Photoredox Catalysis

(2019) Jeremy Nugent et al.   ACS Catalysis

In Situ Generation of Silylzinc by Si−B Bond Activation Enabling Silylzincation and Silaboration of Terminal Alkynes

(2018) Yuki Nagashima et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Modular Approach to the Synthesis of gem-Disubstituted Cyclopropanes

(2018) Michael R. Harris et al.   ORGANIC LETTERS

Synthesis and applications of highly functionalized 1-halo-3-substituted bicyclo[1.1.1]pentanes

(2018) Dimitri F. J. Caputo et al.   Chemical Science

Synthesis of BCP Benzylamines From 2-Azaallyl Anions and [1.1.1]Propellane

(2018) Russell A. Shelp et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonconjugated Hydrocarbons as Rigid-Linear Motifs: Isosteres for Material Sciences and Bioorganic and Medicinal Chemistry

(2018) Gemma M. Locke et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Advances in the Synthetic Chemistry of Bicyclo[1.1.1]pentane

(2018) Junichiro Kanazawa et al.   SYNLETT

Enabling the Cross-Coupling of Tertiary Organoboron Nucleophiles through Radical-Mediated Alkyl Transfer

(2017) David N. Primer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical Multicomponent Carboamination of [1.1.1]Propellane

(2017) Junichiro Kanazawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of 1-Heteroaryl-3-azabicyclo[3.1.0]hexanes by sp3–sp2 Suzuki–Miyaura and Chan–Evans–Lam Coupling Reactions of Tertiary Trifluoroborates

(2017) Michael R. Harris et al.   ORGANIC LETTERS

Development of Enantiospecific Coupling of Secondary and Tertiary Boronic Esters with Aromatic Compounds

(2016) Marcin Odachowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Strain-release amination

(2016) R. Gianatassio et al.   SCIENCE

Synthesis and Biopharmaceutical Evaluation of Imatinib Analogues Featuring Unusual Structural Motifs

(2015) Kyriacos C. Nicolaou et al.   ChemMedChem

Evaluation oftert-Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities

(2015) Matthias V. Westphal et al.   ChemMedChem

Oxalates as Activating Groups for Alcohols in Visible Light Photoredox Catalysis: Formation of Quaternary Centers by Redox-Neutral Fragment Coupling

(2015) Christopher C. Nawrat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereospecific Coupling of Boronic Esters with N-Heteroaromatic Compounds

(2015) Josep Llaveria et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantiospecific sp2–sp3 coupling of secondary and tertiary boronic esters

(2014) Amadeu Bonet et al.   Nature Chemistry

Activation of the Si–B Interelement Bond: Mechanism, Catalysis, and Synthesis

(2012) Martin Oestreich et al.   CHEMICAL REVIEWS

Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

(2012) Antonia F. Stepan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ate Complexes of Secondary Boronic Esters as Chiral Organometallic-Type Nucleophiles for Asymmetric Synthesis

(2011) Robin Larouche-Gauthier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Scalable Synthesis of 1-Bicyclo[1.1.1]pentylamine via a Hydrohydrazination Reaction

(2011) Kevin D. Bunker et al.   ORGANIC LETTERS

Convenient Access to Various 1-Cyclopropylcyclopropane Derivatives

(2010) Armin de Meijere et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Improved method for the conversion of pinacolboronic esters into trifluoroborate salts: facile synthesis of chiral secondary and tertiary trifluoroborates

(2009) Viktor Bagutski et al.   TETRAHEDRON

The Inverted Bond in [1.1.1]Propellane is a Charge-Shift Bond

(2008) Wei Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantiodivergent conversion of chiral secondary alcohols into tertiary alcohols

(2008) Jake L. Stymiest et al.   NATURE