Strain-release amination

Ring-Strain-Enabled Reaction Discovery: New Heterocycles from Bicyclo[1.1.0]butanes

(2015) Maciej A. A. Walczak et al.   ACCOUNTS OF CHEMICAL RESEARCH

Academia–Industry Symbiosis in Organic Chemistry

(2015) Quentin Michaudel et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Thiol-Ene Coupling Approach to Native Peptide Stapling and Macrocyclization

(2015) Yuanxiang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in Chemical Protein Modification

(2015) Omar Boutureira et al.   CHEMICAL REVIEWS

Peptide stapling techniques based on different macrocyclisation chemistries

(2015) Yu Heng Lau et al.   CHEMICAL SOCIETY REVIEWS

Evaluation oftert-Butyl Isosteres: Case Studies of Physicochemical and Pharmacokinetic Properties, Efficacies, and Activities

(2015) Matthias V. Westphal et al.   ChemMedChem

Peptide/Protein Stapling and Unstapling: Introduction of s-Tetrazine, Photochemical Release, and Regeneration of the Peptide/Protein

(2015) Stephen P. Brown et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Good Partnership between Sulfur and Fluorine: Sulfur-Based Fluorination and Fluoroalkylation Reagents for Organic Synthesis

(2014) Chuanfa Ni et al.   CHEMICAL REVIEWS

Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation

(2014) Craig S. McKay et al.   CHEMISTRY & BIOLOGY

Amine Protection/α-Activation with the tert-Butoxythiocarbonyl Group: Application to Azetidine Lithiation–Electrophilic Substitution

(2014) David M. Hodgson et al.   ORGANIC LETTERS

A New Route to Bicyclo[1.1.1]pentan-1-amine from 1-Azido-3-iodobicyclo[1.1.1]pentane

(2014) Yi Ling Goh et al.   ORGANIC LETTERS

Iron- and Cobalt-Catalyzed Arylation of Azetidines, Pyrrolidines, and Piperidines with Grignard Reagents

(2014) Baptiste Barré et al.   ORGANIC LETTERS

Adamantylation of saturated nitrogen-containing heterocycles

(2014) G. M. Butov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Exploration of 3-Aminoazetidines as Triple Reuptake Inhibitors by Bioisosteric Modification of 3-α-Oxyazetidine

(2014) Minsoo Han et al.   ACS Medicinal Chemistry Letters

A Perfluoroaryl-Cysteine SNAr Chemistry Approach to Unprotected Peptide Stapling

(2013) Alexander M. Spokoyny et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

(2012) Antonia F. Stepan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iridium-Catalyzed Reduction of Secondary Amides to Secondary Amines and Imines by Diethylsilane

(2012) Chen Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Practical and innate carbon–hydrogen functionalization of heterocycles

(2012) Yuta Fujiwara et al.   NATURE

The conjugate addition of enantiomerically pure lithium amides as chiral ammonia equivalents part II: 2005−2011

(2012) Stephen G. Davies et al.   TETRAHEDRON-ASYMMETRY

Optimization of Potent, Selective, and Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors of Heat Shock Protein 90. Identification of Development Candidate 2-Amino-4-{4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl}-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide

(2011) Luke Zehnder et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evaluation of Quinazoline Analogues as Glucocerebrosidase Inhibitors with Chaperone Activity

(2011) Juan J. Marugan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Choosing an effective protein bioconjugation strategy

(2011) Nicholas Stephanopoulos et al.   Nature Chemical Biology

Scalable Synthesis of 1-Bicyclo[1.1.1]pentylamine via a Hydrohydrazination Reaction

(2011) Kevin D. Bunker et al.   ORGANIC LETTERS

Synthesis of Multi-Substituted Cyclobutanes and Alkylidenecyclobutanes by the Reaction of Cyclobutylmagnesium Carbenoids with Nucleophiles

(2011) Tsuyoshi Satoh et al.   SYNTHESIS-STUTTGART

C-2 Arylation of Piperidines through Directed Transition-Metal-Catalyzed sp3CH Activation

(2010) Hana Prokopcová et al.   CHEMISTRY-A EUROPEAN JOURNAL

Advances in Bioconjugation

(2009) Jeet Kalia et al.   CURRENT ORGANIC CHEMISTRY

A Biomimetic Electrocatalytic System for the Atom-Economical Chemoselective Synthesis of Secondary Amines

(2009) Martine Largeron et al.   ORGANIC LETTERS

A General Method formeta andpara Functionalization of Arenes Using TMP2Mg⋅2 LiCl

(2008) Christoph J. Rohbogner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of New Quinolone Antibiotics Utilizing Azetidine Derivatives Obtained from 1-Azabicyclo[1.1.0]butane

(2008) Yoshifumi Ikee et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Novel Syntheses of Azetidines and Azetidinones

(2008) Alberto Brandi et al.   CHEMICAL REVIEWS