Epigenetic down regulation of G protein-coupled estrogen receptor (GPER) functions as a tumor suppressor in colorectal cancer

Estrogen receptor beta as target for colorectal cancer prevention

(2016) Cecilia Williams et al.   CANCER LETTERS

Activation of GPER suppresses epithelial mesenchymal transition of triple negative breast cancer cells via NF-κB signals

(2016) Zhuo-Jia Chen et al.   Molecular Oncology

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/β-catenin signalling pathway via suppression of activator protein 2α

(2015) Yanlei Ma et al.   GUT

Aldosterone stimulates the cardiac sodium/bicarbonate cotransporter via activation of the g protein-coupled receptor gpr30

(2015) Verónica C. De Giusti et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

40-year trends in an index of survival for all cancers combined and survival adjusted for age and sex for each cancer in England and Wales, 1971–2011: a population-based study

(2015) Manuela Quaresma et al.   LANCET

SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer

(2015) M F Santolla et al.   Cell Death & Disease

GPER functions as a tumor suppressor in MCF-7 and SK-BR-3 breast cancer cells

(2014) Christine Weißenborn et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Involvement of activating ERK1/2 through G protein coupled receptor 30 and estrogen receptor α/β in low doses of bisphenol A promoting growth of Sertoli TM4 cells

(2014) Li-Chen Ge et al.   TOXICOLOGY LETTERS

The activation of G protein-coupled receptor 30 (GPR30) inhibits proliferation of estrogen receptor-negative breast cancer cells in vitro and in vivo

(2014) W Wei et al.   Cell Death & Disease

GPER-1 Expression Decreases During Breast Cancer Tumorigenesis

(2013) Tanja Ignatov et al.   CANCER INVESTIGATION

GPER activates Notch signaling in breast cancer cells and cancer-associated fibroblasts (CAFs)

(2013) Marco Pupo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Estrogen Signaling through the G Protein-Coupled Estrogen Receptor Regulates Granulocyte Activation in Fish

(2013) I. Cabas et al.   JOURNAL OF IMMUNOLOGY

Selective GPER activation decreases proliferation and activates apoptosis in tumor Leydig cells

(2013) A Chimento et al.   Cell Death & Disease

The G-protein-coupled estrogen receptor agonist G-1 suppresses proliferation of ovarian cancer cells by blocking tubulin polymerization

(2013) C Wang et al.   Cell Death & Disease

GPER-1 acts as a tumor suppressor in ovarian cancer

(2013) Tanja Ignatov et al.   Journal of Ovarian Research

Expression of oestrogen receptor β and prognosis of colorectal cancer

(2012) A Rudolph et al.   BRITISH JOURNAL OF CANCER

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Estrogen receptor-β protects against colitis-associated neoplasia in mice

(2012) Diana Saleiro et al.   INTERNATIONAL JOURNAL OF CANCER

Estrogenic transmembrane receptor of GPR30 mediates invasion and carcinogenesis by endometrial cancer cell line RL95-2

(2012) Yin-Yan He et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Estrogen Plus Progestin and Colorectal Cancer Incidence and Mortality

(2012) Michael S. Simon et al.   JOURNAL OF CLINICAL ONCOLOGY

The G protein-coupled estrogen receptor 1 (GPER/GPR30) does not predict survival in patients with ovarian cancer

(2012) Zuzana Kolkova et al.   Journal of Ovarian Research

Diacylglycerol kinase α mediates 17-β-estradiol-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line through the G protein-coupled estrogen receptor GPR30

(2011) Nicoletta Filigheddu et al.   CELLULAR SIGNALLING

The effect of estrogen vs. combined estrogen-progestogen therapy on the risk of colorectal cancer

(2011) Kueiyu Joshua Lin et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting Sarcoplasmic/Endoplasmic Reticulum Ca2+-ATPase 2 by Curcumin Induces ER Stress-Associated Apoptosis for Treating Human Liposarcoma

(2011) L. Wang et al.   MOLECULAR CANCER THERAPEUTICS

The G-protein-coupled estrogen receptor GPER in health and disease

(2011) Eric R. Prossnitz et al.   Nature Reviews Endocrinology

Targeting ER stress induced apoptosis and inflammation in cancer

(2010) Tom Verfaillie et al.   CANCER LETTERS

The G Protein-Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor-Positive Breast Cancer Cells

(2010) E. A. Ariazi et al.   CANCER RESEARCH

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

(2010) Yohannes Mebratu et al.   CELL CYCLE

Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21 and induction of G2 cell-cycle arrest

(2010) Q K Y Chan et al.   CELL DEATH AND DIFFERENTIATION

Modeling Oncogenic Signaling in Colon Tumors by Multidirectional Analyses of Microarray Data Directed for Maximization of Analytical Reliability

(2010) Magdalena Skrzypczak et al.   PLoS One

Tumor Repressive Functions of Estrogen Receptor   in SW480 Colon Cancer Cells

(2009) J. Hartman et al.   CANCER RESEARCH

Estradiol Alters Cell Growth in Nonmalignant Colonocytes and Reduces the Formation of Preneoplastic Lesions in the Colon

(2009) C. C. Weige et al.   CANCER RESEARCH

Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

(2009) Deo Prakash Pandey et al.   EMBO JOURNAL

GPR30 predicts poor survival for ovarian cancer

(2009) Harriet O. Smith et al.   GYNECOLOGIC ONCOLOGY

Glycogen Synthase Kinase-3 Inhibition Induces Glioma Cell Death through c-MYC, Nuclear Factor- B, and Glucose Regulation

(2008) S. Kotliarova et al.   CANCER RESEARCH