Ketamine Increases Proliferation of Human iPSC-Derived Neuronal Progenitor Cells via Insulin-Like Growth Factor 2 and Independent of the NMDA Receptor

Esketamine for Treatment-Resistant Depression — First FDA-Approved Antidepressant in a New Class

(2019) Jean Kim et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Hippocampal Neurogenesis Persists throughout Aging

(2018) Maura Boldrini et al.   Cell Stem Cell

NMDAR-independent, cAMP-dependent antidepressant actions of ketamine

(2018) Nathan H. Wray et al.   MOLECULAR PSYCHIATRY

Mechanisms of ketamine action as an antidepressant

(2018) P Zanos et al.   MOLECULAR PSYCHIATRY

Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

(2018) Panos Zanos et al.   PHARMACOLOGICAL REVIEWS

Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation

(2018) Daniel Simão et al.   Stem Cell Reports

Insulin growth factor 2 (IGF2) as an emergent target in psychiatric and neurological disorders. Review

(2018) M. Pardo et al.   NEUROSCIENCE RESEARCH

Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit

(2017) N Yao et al.   MOLECULAR PSYCHIATRY

Up-regulation of insulin-like growth factor 2 by ketamine requires glycogen synthase kinase-3 inhibition

(2017) Steven F. Grieco et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response

(2017) Zhenzhong Ma et al.   Nature Communications

Ketamine: NMDA Receptors and Beyond

(2016) C. F. Zorumski et al.   JOURNAL OF NEUROSCIENCE

cAMP signaling in brain is decreased in unmedicated depressed patients and increased by treatment with a selective serotonin reuptake inhibitor

(2016) M Fujita et al.   MOLECULAR PSYCHIATRY

Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown

(2016) Mihaela Pertea et al.   Nature Protocols

Role of hippocampal p11 in the sustained antidepressant effect of ketamine in the chronic unpredictable mild stress model

(2016) H-L Sun et al.   Translational Psychiatry

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Antidepressant mechanism of ketamine: perspective from preclinical studies

(2015) Lisa Scheuing et al.   Frontiers in Neuroscience

Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons

(2014) Jeffrey L. Dage et al.   PSYCHOPHARMACOLOGY

Stress susceptibility-specific phenotype associated with different hippocampal transcriptomic responses to chronic tricyclic antidepressant treatment in mice

(2013) Pawel Lisowski et al.   BMC NEUROSCIENCE

Antidepressant Augmentation Using theN-Methyl-d-Aspartate Antagonist Memantine

(2013) Eric G. Smith et al.   JOURNAL OF CLINICAL PSYCHIATRY

p11 and its role in depression and therapeutic responses to antidepressants

(2013) Per Svenningsson et al.   NATURE REVIEWS NEUROSCIENCE

Neural Plasticity and Proliferation in the Generation of Antidepressant Effects: Hippocampal Implication

(2013) Fuencisla Pilar-Cuéllar et al.   NEURAL PLASTICITY

Gene Expression Profiling of Neural Stem Cells and Their Neuronal Progeny Reveals IGF2 as a Regulator of Adult Hippocampal Neurogenesis

(2012) O. Bracko et al.   JOURNAL OF NEUROSCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

A critical role for IGF-II in memory consolidation and enhancement

(2011) Dillon Y. Chen et al.   NATURE

Neurogenic Effects of Fluoxetine Are Attenuated in p11 (S100A10) Knockout Mice

(2010) Martin Egeland et al.   BIOLOGICAL PSYCHIATRY

A Role for p11 in the Antidepressant Action of Brain-Derived Neurotrophic Factor

(2010) Jennifer L. Warner-Schmidt et al.   BIOLOGICAL PSYCHIATRY

Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models

(2010) B M Andrus et al.   MOLECULAR PSYCHIATRY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Rapid Onset of Antidepressant Action

(2009) Rodrigo Machado-Vieira et al.   JOURNAL OF CLINICAL PSYCHIATRY

Antidepressants increase neural progenitor cells in the human hippocampus

(2009) Maura Boldrini et al.   NEUROPSYCHOPHARMACOLOGY

In-vitro effects of brain-derived neurotrophic factor on neural progenitor/stem cells from rat hippocampus

(2009) Tingsong Li et al.   NEUROREPORT

Erk1/2 promotes proliferation and inhibits neuronal differentiation of neural stem cells

(2009) Bin Wang et al.   NEUROSCIENCE LETTERS

A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration

(2009) P. Koch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA