Formation of COPI-coated vesicles at a glance

Regulation of Arf activation occurs via distinct mechanisms at early and late Golgi compartments

(2017) Margaret A. Gustafson et al.   MOLECULAR BIOLOGY OF THE CELL

COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal

(2017) Peng Xu et al.   eLife

9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments

(2017) Svetlana O Dodonova et al.   eLife

The structure of the COPI coat determined within the cell

(2017) Yury S Bykov et al.   eLife

ARCN1 Mutations Cause a Recognizable Craniofacial Syndrome Due to COPI-Mediated Transport Defects

(2016) Kosuke Izumi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ER arrival sites for COPI vesicles localize to hotspots of membrane trafficking

(2016) Saskia Schröter et al.   EMBO JOURNAL

A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1

(2016) Markus Kilisch et al.   JOURNAL OF CELL SCIENCE

δ-COP modulates Aβ peptide formation via retrograde trafficking of APP

(2016) Karima Bettayeb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relevance of the COPI complex for Alzheimer’s disease progression in vivo

(2016) Karima Bettayeb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

δ-COP contains a helix C-terminal to its longin domain key to COPI dynamics and function

(2016) Eric C. Arakel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Essential Role for COPI in mRNA Localization to Mitochondria and Mitochondrial Function

(2016) Dmitry Zabezhinsky et al.   Cell Reports

Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi

(2016) Antonio Galindo et al.   Cell Reports

Structural characterization of coatomer in its cytosolic state

(2016) Shengliu Wang et al.   Protein & Cell

Missense-depleted regions in population exomes implicate ras superfamily nucleotide-binding protein alteration in patients with brain malformation

(2016) Xiaoyan Ge et al.   npj Genomic Medicine

The Erv41–Erv46 complex serves as a retrograde receptor to retrieve escaped ER proteins

(2015) Aya Shibuya et al.   JOURNAL OF CELL BIOLOGY

Coordinated regulation of bidirectional COPI transport at the Golgi by CDC42

(2015) Seung-Yeol Park et al.   NATURE

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis

(2015) Levi B Watkin et al.   NATURE GENETICS

Structural basis for the binding of tryptophan-based motifs by δ-COP

(2015) Richard J. Suckling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structure of the COPI coat and the role of coat proteins in membrane vesicle assembly

(2015) S. O. Dodonova et al.   SCIENCE

Structure of the bovine COPI δ subunit μ homology domain at 2.15 Å resolution

(2015) Avital Lahav et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Golgi Phosphoprotein 3 Triggers Signal-mediated Incorporation of Glycosyltransferases into Coatomer-coated (COPI) Vesicles

(2014) Elias S. P. Eckert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tuning the electrical properties of the heart by differential trafficking of KATP ion channel complexes

(2014) E. C. Arakel et al.   JOURNAL OF CELL SCIENCE

Scyl1 scaffolds class II Arfs to specific subcomplexes of coatomer through the  -COP appendage domain

(2014) J. N. R. Hamlin et al.   JOURNAL OF CELL SCIENCE

Contact of cis-Golgi with ER exit sites executes cargo capture and delivery from the ER

(2014) Kazuo Kurokawa et al.   Nature Communications

Characterization of TSET, an ancient and widespread membrane trafficking complex

(2014) Jennifer Hirst et al.   eLife

Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1

(2013) Xuefeng Ren et al.   CELL

Rules for the recognition of dilysine retrieval motifs by coatomer

(2013) Wenfu Ma et al.   EMBO JOURNAL

COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function

(2013) A. R. Thiam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Scission of COPI and COPII Vesicles Is Independent of GTP Hydrolysis

(2013) Frank Adolf et al.   TRAFFIC

Longin and GAF Domains: Structural Evolution and Adaptation to the Subcellular Trafficking Machinery

(2013) Nicola De Franceschi et al.   TRAFFIC

Vesicle coats: structure, function, and general principles of assembly

(2013) Marco Faini et al.   TRENDS IN CELL BIOLOGY

A Structure-Based Mechanism for Arf1-Dependent Recruitment of Coatomer to Membranes

(2012) Xinchao Yu et al.   CELL

Molecular Basis for Recognition of Dilysine Trafficking Motifs by COPI

(2012) Lauren P. Jackson et al.   DEVELOPMENTAL CELL

COPI transport complexes bind to specific RNAs in neuronal cells

(2012) Adrian G. Todd et al.   HUMAN MOLECULAR GENETICS

Molecular Insights into Vesicle Tethering at the Golgi by the Conserved Oligomeric Golgi (COG) Complex and the Golgin TATA Element Modulatory Factor (TMF)

(2012) Victoria J. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Structures of COPI-Coated Vesicles Reveal Alternate Coatomer Conformations and Interactions

(2012) M. Faini et al.   SCIENCE

A Conserved N-terminal Arginine-Motif in GOLPH3-Family Proteins Mediates Binding to Coatomer

(2012) Linna Tu et al.   TRAFFIC

Several ADP-ribosylation Factor (Arf) Isoforms Support COPI Vesicle Formation

(2011) Vincent Popoff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coatomer and dimeric ADP ribosylation factor 1 promote distinct steps in membrane scission

(2011) Rainer Beck et al.   JOURNAL OF CELL BIOLOGY

Molecular Structure and Flexibility of the Yeast Coatomer as Revealed by Electron Microscopy

(2011) Calvin K. Yip et al.   JOURNAL OF MOLECULAR BIOLOGY

Recombinant Heptameric Coatomer Complexes: Novel Tools to Study Isoform-Specific Functions

(2011) Monika C. Sahlmüller et al.   TRAFFIC

ArfGAP1 interacts with coat proteins through tryptophan-based motifs

(2010) Moran Rawet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure of Coatomer Cage Proteins and the Relationship among COPI, COPII, and Clathrin Vesicle Coats

(2010) Changwook Lee et al.   CELL

A Large-Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the AP2 Clathrin Adaptor Complex

(2010) Lauren P. Jackson et al.   CELL

Arf GAPs: Gatekeepers of vesicle generation

(2010) Anne Spang et al.   FEBS LETTERS

ARFGAP2 and ARFGAP3 Are Essential for COPI Coat Assembly on the Golgi Membrane of Living Cells

(2010) Fredrik Kartberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective export of human GPI-anchored proteins from the endoplasmic reticulum

(2010) C. Bonnon et al.   JOURNAL OF CELL SCIENCE

Scyl1 Regulates Golgi Morphology

(2010) Jonathon L. Burman et al.   PLoS One

Mutation in Archain 1, a Subunit of COPI Coatomer Complex, Causes Diluted Coat Color and Purkinje Cell Degeneration

(2010) Xinjie Xu et al.   PLoS Genetics

A Structure-Based Mechanism for Vesicle Capture by the Multisubunit Tethering Complex Dsl1

(2009) Yi Ren et al.   CELL

Arf GAP2 is positively regulated by coatomer and cargo

(2009) Ruibai Luo et al.   CELLULAR SIGNALLING

On vesicle formation and tethering in the ER–Golgi shuttle

(2009) Anne Spang   CURRENT OPINION IN CELL BIOLOGY

A Link between ER Tethering and COP-I Vesicle Uncoating

(2009) Sabrina Zink et al.   DEVELOPMENTAL CELL

Early endosomes and endosomal coatomer are required for autophagy

(2009) Minoo Razi et al.   JOURNAL OF CELL BIOLOGY

Coatomer-dependent protein delivery to lipid droplets

(2009) K. G. Soni et al.   JOURNAL OF CELL SCIENCE

mTrs130 Is a Component of a Mammalian TRAPPII Complex, a Rab1 GEF That Binds to COPI-coated Vesicles

(2009) Akinori Yamasaki et al.   MOLECULAR BIOLOGY OF THE CELL

The GAP Domain and the SNARE, Coatomer and Cargo Interaction Region of the ArfGAP2/3 Glo3 are Sufficient for Glo3 Function

(2009) Christina Schindler et al.   TRAFFIC

Ypt11 Functions in Bud-Directed Transport of the Golgi by Linking Myo2 to the Coatomer Subunit Ret2

(2008) Seisuke Arai et al.   CURRENT BIOLOGY

A COPI coat subunit interacts directly with an early-Golgi localized Arf exchange factor

(2008) Yi Deng et al.   EMBO REPORTS

Kinetic Analysis of Arf GAP1 Indicates a Regulatory Role for Coatomer

(2008) Ruibai Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arf1-GTP-induced Tubule Formation Suggests a Function of Arf Family Proteins in Curvature Acquisition at Sites of Vesicle Budding

(2008) Michael Krauss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking

(2008) Carolin Weimer et al.   JOURNAL OF CELL BIOLOGY

The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus

(2008) Auxiliadora Aguilera-Romero et al.   JOURNAL OF CELL BIOLOGY

Coat-Tether Interaction in Golgi Organization

(2008) Yusong Guo et al.   MOLECULAR BIOLOGY OF THE CELL

Discrete Determinants in ArfGAP2/3 Conferring Golgi Localization and Regulation by the COPI Coat

(2008) Lena Kliouchnikov et al.   MOLECULAR BIOLOGY OF THE CELL

A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenance

(2008) Jia-Shu Yang et al.   NATURE CELL BIOLOGY

COPI coat assembly occurs on liquid-disordered domains and the associated membrane deformations are limited by membrane tension

(2008) J.-B. Manneville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane curvature induced by Arf1-GTP is essential for vesicle formation

(2008) R. Beck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signal-Mediated Dynamic Retention of Glycosyltransferases in the Golgi

(2008) L. Tu et al.   SCIENCE

A Conformational Change in the α-subunit of Coatomer Induced by Ligand Binding to γ-COP Revealed by Single-pair FRET

(2008) Julian D. Langer et al.   TRAFFIC

ArfGAP1 Activity and COPI Vesicle Biogenesis

(2008) Rainer Beck et al.   TRAFFIC

COPI Complex Is a Regulator of Lipid Homeostasis

(2008) Mathias Beller et al.   PLOS BIOLOGY