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Title
The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases
Authors
Keywords
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Journal
Frontiers in Endocrinology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-08-27
DOI
10.3389/fendo.2019.00585
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- (2009) Andrea Reboldi et al. NATURE IMMUNOLOGY
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- (2007) M LI et al. PROGRESS IN NEUROBIOLOGY
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