Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

Mutations in ERCC4, Encoding the DNA-Repair Endonuclease XPF, Cause Fanconi Anemia

(2013) Massimo Bogliolo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway

(2012) A. M. Ali et al.   BLOOD

Germline mutations in BRIP1 and PALB2 in Jewish high cancer risk families

(2012) Irene Catucci et al.   Familial Cancer

Rare germline mutations inPALB2and breast cancer risk: A population-based study

(2012) Marc Tischkowitz et al.   HUMAN MUTATION

Molecular pathogenesis and clinical management of Fanconi anemia

(2012) Younghoon Kee et al.   JOURNAL OF CLINICAL INVESTIGATION

Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway

(2012) J. Chun et al.   MOLECULAR AND CELLULAR BIOLOGY

BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer

(2011) Michelle W. Wong et al.   BREAST CANCER RESEARCH AND TREATMENT

Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility

(2011) Mikko Vuorela et al.   BREAST CANCER RESEARCH AND TREATMENT

Novel germline PALB2 truncating mutations in African American breast cancer patients

(2011) Yonglan Zheng et al.   CANCER

Contribution of Inherited Mutations in the BRCA2-Interacting Protein PALB2 to Familial Breast Cancer

(2011) S. Casadei et al.   CANCER RESEARCH

PALB2 mutations in familial breast and pancreatic cancer

(2011) Erin W. Hofstatter et al.   Familial Cancer

Germline mutations in the PALB2 gene are population specific and occur with low frequencies in familial breast cancer

(2011) Heide Hellebrand et al.   HUMAN MUTATION

Distinct Roles of FANCO/RAD51C Protein in DNA Damage Signaling and Repair

(2011) Kumar Somyajit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Germline mutations in PALB2 in African-American breast cancer cases

(2010) Yuan Chun Ding et al.   BREAST CANCER RESEARCH AND TREATMENT

PALB2 analysis in BRCA2-like families

(2010) M. A. Adank et al.   BREAST CANCER RESEARCH AND TREATMENT

PALB2 mutations in German and Russian patients with bilateral breast cancer

(2010) Natalia Bogdanova et al.   BREAST CANCER RESEARCH AND TREATMENT

PALB2: a novel inactivating mutation in a Italian breast cancer family

(2010) Cristina Balia et al.   Familial Cancer

MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks

(2010) T. Hayakawa et al.   JOURNAL OF CELL SCIENCE

MHF1-MHF2, a Histone-Fold-Containing Protein Complex, Participates in the Fanconi Anemia Pathway via FANCM

(2010) Thiyam Ramsing Singh et al.   MOLECULAR CELL

Structure of RCC1 chromatin factor bound to the nucleosome core particle

(2010) Ravindra D. Makde et al.   NATURE

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

(2010) Alfons Meindl et al.   NATURE GENETICS

Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination

(2010) Rémi Buisson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2

(2010) Eloïse Dray et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

WD40 proteins propel cellular networks

(2010) Christian U. Stirnimann et al.   TRENDS IN BIOCHEMICAL SCIENCES

The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51

(2009) Aura Carreira et al.   CELL

PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

(2009) Feng Zhang et al.   CURRENT BIOLOGY

Fanconi Anemia Proteins, DNA Interstrand Crosslink Repair Pathways, and Cancer Therapy

(2009) Paul Andreassen et al.   CURRENT CANCER DRUG TARGETS

Structural basis for recruitment of BRCA2 by PALB2

(2009) Antony W Oliver et al.   EMBO REPORTS

PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2

(2009) F. Zhang et al.   MOLECULAR CANCER RESEARCH

RAD18 transmits DNA damage signalling to elicit homologous recombination repair

(2009) Jun Huang et al.   NATURE CELL BIOLOGY

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

(2009) S. M. H. Sy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Predisposition to Breast Cancer: Past, Present, and Future

(2008) Clare Turnbull et al.   Annual Review of Genomics and Human Genetics

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

(2008) J B Wilson et al.   ONCOGENE