Therapeutic Targeting of MZF1‐AS1 /PARP1/E2F1 Axis Inhibits Proline Synthesis and Neuroblastoma Progression

Long Noncoding RNA pancEts-1 Promotes Neuroblastoma Progression through hnRNPK-Mediated β-Catenin Stabilization

(2018) Dan Li et al.   CANCER RESEARCH

Loss of the Nuclear Pool of Ubiquitin Ligase CHIP/STUB1 in Breast Cancer Unleashes the MZF1-Cathepsin Pro-oncogenic Program

(2018) Haitao Luan et al.   CANCER RESEARCH

HPSE enhancer RNA promotes cancer progression through driving chromatin looping and regulating hnRNPU/p300/EGR1/HPSE axis

(2018) Wanju Jiao et al.   ONCOGENE

Angiogenic patterning by STEEL, an endothelial-enriched long noncoding RNA

(2018) H. S. Jeffrey Man et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Precision Targeted Therapy with BLU-667 for RET -Driven Cancers

(2018) Vivek Subbiah et al.   Cancer Discovery

E2F1 silencing inhibits migration and invasion of osteosarcoma cells via regulating DDR1 expression

(2017) Zhaofeng Wang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer

(2017) Tengyue Zeng et al.   MEDICAL ONCOLOGY

EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer

(2017) H Yamaguchi et al.   ONCOGENE

E2F1 induces TINCR transcriptional activity and accelerates gastric cancer progression via activation of TINCR/STAU1/CDKN2B signaling axis

(2017) Tong-Peng Xu et al.   Cell Death & Disease

An Update on Poly(ADP-ribose)polymerase-1 (PARP-1) Inhibitors: Opportunities and Challenges in Cancer Therapy

(2016) Ying-Qing Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tumour-specific proline vulnerability uncovered by differential ribosome codon reading

(2016) Fabricio Loayza-Puch et al.   NATURE

The BioGRID interaction database: 2017 update

(2016) Andrew Chatr-aryamontri et al.   NUCLEIC ACIDS RESEARCH

PARP1 enhances lung adenocarcinoma metastasis by novel mechanisms independent of DNA repair

(2016) E-B Choi et al.   ONCOGENE

Functional Characterization of Long Noncoding RNA Lnc_bc060912 in Human Lung Carcinoma Cells

(2015) Huaxia Luo et al.   BIOCHEMISTRY

Proline metabolism and cancer

(2015) James M. Phang et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Advances in Risk Classification and Treatment Strategies for Neuroblastoma

(2015) Navin R. Pinto et al.   JOURNAL OF CLINICAL ONCOLOGY

Bimolecular Fluorescence Complementation (BiFC) Analysis: Advances and Recent Applications for Genome-Wide Interaction Studies

(2015) Kristi E. Miller et al.   JOURNAL OF MOLECULAR BIOLOGY

Intelectin 1 suppresses the growth, invasion and metastasis of neuroblastoma cells through up-regulation of N-myc downstream regulated gene 2

(2015) Dan Li et al.   Molecular Cancer

Disruption of Proline Synthesis in Melanoma Inhibits Protein Production Mediated by the GCN2 Pathway

(2015) G. R. Kardos et al.   MOLECULAR CANCER RESEARCH

CTCF cooperates with noncoding RNA MYCNOS to promote neuroblastoma progression through facilitating MYCN expression

(2015) X Zhao et al.   ONCOGENE

Differential regulation of MMPs by E2F1, Sp1 and NF-kappa B controls the small cell lung cancer invasive phenotype

(2014) Zunling Li et al.   BMC CANCER

The Risk-Associated Long Noncoding RNA NBAT-1 Controls Neuroblastoma Progression by Regulating Cell Proliferation and Neuronal Differentiation

(2014) Gaurav Kumar Pandey et al.   CANCER CELL

Regulation of E2F1-induced apoptosis by poly(ADP-ribosyl)ation

(2014) A Kumari et al.   CELL DEATH AND DIFFERENTIATION

C-KIT Signaling in Cancer Treatment

(2014) Karmen Stankov et al.   CURRENT PHARMACEUTICAL DESIGN

RNABindRPlus: A Predictor that Combines Machine Learning and Sequence Homology-Based Methods to Improve the Reliability of Predicted RNA-Binding Residues in Proteins

(2014) Rasna R. Walia et al.   PLoS One

Myeloid zinc finger 1 mediates sulindac sulfide-induced upregulation of death receptor 5 of human colon cancer cells

(2014) Mano Horinaka et al.   Scientific Reports

Up-Regulation of FOXM1 by E6 Oncoprotein through the MZF1/NKX2-1 Axis Is Required for Human Papillomavirus–Associated Tumorigenesis

(2014) Po-Ming Chen et al.   NEOPLASIA

catRAPID omics: a web server for large-scale prediction of protein-RNA interactions

(2013) F. Agostini et al.   BIOINFORMATICS

E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B

(2013) David Engelmann et al.   Journal of Molecular Cell Biology

Inheritance of Silent rDNA Chromatin Is Mediated by PARP1 via Noncoding RNA

(2012) Claudio Guetg et al.   MOLECULAR CELL

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

(2012) Jan J. Molenaar et al.   NATURE

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC

(2012) W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic Profiling Identifies Dysregulated Pathways in Small Cell Lung Cancer and Novel Therapeutic Targets Including PARP1

(2012) Lauren Averett Byers et al.   Cancer Discovery

The Proline Regulatory Axis and Cancer

(2012) James Ming Phang et al.   Frontiers in Oncology

PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions

(2011) M. F. Lin et al.   BIOINFORMATICS

Genome-wide Analysis of Transcription Factor E2F1 Mutant Proteins Reveals That N- and C-terminal Protein Interaction Domains Do Not Participate in Targeting E2F1 to the Human Genome

(2011) Alina R. Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments

(2010) Alexander Lachmann et al.   BIOINFORMATICS

E2F1 in Melanoma Progression and Metastasis

(2009) Vijay Alla et al.   JNCI-Journal of the National Cancer Institute