E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B

The Dark Side of E2F1: In Transit beyond Apoptosis

(2012) D. Engelmann et al.   CANCER RESEARCH

E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry

(2012) Vijay Alla et al.   CELL CYCLE

E2F1 apoptosis counterattacked: evil strikes back

(2012) Brigitte M. Pützer et al.   TRENDS IN MOLECULAR MEDICINE

Regulation of Matrix Metalloproteinase Genes by E2F Transcription Factors: Rb-Raf-1 Interaction as a Novel Target for Metastatic Disease

(2011) J. L. Johnson et al.   CANCER RESEARCH

Vascular endothelial growth factor receptor-3 promotes breast cancer cell proliferation, motility and survival in vitro and tumor formation in vivo

(2011) Elena V. Kurenova et al.   CELL CYCLE

ATM and p53 Regulate FOXM1 Expression via E2F in Breast Cancer Epirubicin Treatment and Resistance

(2011) J. Millour et al.   MOLECULAR CANCER THERAPEUTICS

Regulation of Vascular Endothelial Growth Factor Receptors by Rb and E2F1: Role of Acetylation

(2010) Smitha Pillai et al.   CANCER RESEARCH

ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2

(2010) E. V. Kalashnikova et al.   CANCER RESEARCH

GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria

(2010) K John et al.   CELL DEATH AND DIFFERENTIATION

Translating DNA damage into cancer cell death—A roadmap for E2F1 apoptotic signalling and opportunities for new drug combinations to overcome chemoresistance

(2010) David Engelmann et al.   DRUG RESISTANCE UPDATES

Evading tumor evasion: Current concepts and perspectives of anti-angiogenic cancer therapy

(2010) Amir Abdollahi et al.   DRUG RESISTANCE UPDATES

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

(2010) Ankur Sharma et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression Signature of E2F1 and Its Associated Genes Predict Superficial to Invasive Progression of Bladder Tumors

(2010) Ju-Seog Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

Chromatin Loading of E2F-MLL Complex by Cancer-Associated Coregulator ANCCA via Reading a Specific Histone Mark

(2010) A. S. Revenko et al.   MOLECULAR AND CELLULAR BIOLOGY

The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo

(2010) G Merdzhanova et al.   ONCOGENE

VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B

(2009) Mitsuho Onimaru et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Co-expression of PDGF-B and VEGFR-3 strongly correlates with lymph node metastasis and poor survival in non-small-cell lung cancer

(2009) T. Donnem et al.   ANNALS OF ONCOLOGY

Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF- B and Prox1

(2009) M. J. Flister et al.   BLOOD

Gonadotropin-Regulated Lymphangiogenesis in Ovarian Cancer Is Mediated by LEDGF-Induced Expression of VEGF-C

(2009) S. Sapoznik et al.   CANCER RESEARCH

Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGF-R3/JNK/ AP-1 pathway

(2009) Ming-Hsien Chien et al.   CARCINOGENESIS

Functional interplay between E2F1 and chemotherapeutic drugs defines immediate E2F1 target genes crucial for cancer cell death

(2009) David Engelmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

E2F1 in Melanoma Progression and Metastasis

(2009) Vijay Alla et al.   JNCI-Journal of the National Cancer Institute

Division and apoptosis of E2f-deficient retinal progenitors

(2009) Danian Chen et al.   NATURE

The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis

(2009) Giulia Fontemaggi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

In vivoanalysis of biocompatibility and vascularization of the synthetic bone grafting substitute NanoBone®

(2008) K. Abshagen et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

(2008) Tuomas Tammela et al.   NATURE