The Comet Assay as a Tool to Detect the Genotoxic Potential of Nanomaterials

Shape-engineered titanium dioxide nanoparticles (TiO2-NPs): cytotoxicity and genotoxicity in bronchial epithelial cells

(2019) Marta Gea et al.   FOOD AND CHEMICAL TOXICOLOGY

Nanoceria acts as antioxidant in tumoral and transformed cells

(2018) Laura Rubio et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Differential pulmonary in vitro toxicity of two small-sized polyvinylpyrrolidone-coated silver nanoparticles

(2018) Fernanda Rosário et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Assessment of the in vitro genotoxicity of TiO2 nanoparticles in a regulatory context

(2018) Sandrine Charles et al.   Nanotoxicology

Genotoxicity Assessment of Nanomaterials: Recommendations on Best Practices, Assays, and Methods

(2018) Rosalie Elespuru et al.   TOXICOLOGICAL SCIENCES

Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: A review

(2018) Niels Hadrup et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Zinc oxide nanoparticles impacts: cytotoxicity, genotoxicity, developmental toxicity, and neurotoxicity

(2018) Sanjiv Singh   TOXICOLOGY MECHANISMS AND METHODS

Genotoxicity of amorphous silica nanoparticles: Status and prospects

(2018) Mostafa Yazdimamaghani et al.   Nanomedicine-Nanotechnology Biology and Medicine

Review of toxicity studies of carbon nanotubes

(2017) Norihiro Kobayashi et al.   JOURNAL OF OCCUPATIONAL HEALTH

Recent advances (2010–2015) in studies of cerium oxide nanoparticles’ health effects

(2016) Yan Li et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Comparative genotoxicity of silver nanoparticles in human liver HepG2 and lung epithelial A549 cells

(2016) J. Wang et al.   JOURNAL OF APPLIED TOXICOLOGY

Comparison of the DNA damage response in BEAS-2B and A549 cells exposed to titanium dioxide nanoparticles

(2016) M. Biola-Clier et al.   MUTAGENESIS

Genotoxicity of TiO2nanoparticles assessed by mini-gel comet assay and micronucleus scoring with flow cytometry

(2016) Sebastiano Di Bucchianico et al.   MUTAGENESIS

In vitrogenotoxicity testing of four reference metal nanomaterials, titanium dioxide, zinc oxide, cerium oxide and silver: towards reliable hazard assessment

(2016) Naouale El Yamani et al.   MUTAGENESIS

Effect of particle size and dispersion status on cytotoxicity and genotoxicity of zinc oxide in human bronchial epithelial cells

(2016) Joanna Roszak et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

In vitroandin vivogenotoxic effects of straight versus tangled multi-walled carbon nanotubes

(2016) Julia Catalán et al.   Nanotoxicology

Frozen dispersions of nanomaterials are a useful operational procedure in nanotoxicology

(2016) Laura Vila et al.   Nanotoxicology

Long-term exposure of A549 cells to titanium dioxide nanoparticles induces DNA damage and sensitizes cells towards genotoxic agents

(2016) Lucie Armand et al.   Nanotoxicology

Evaluation of the cytotoxic and genotoxic effects of benchmark multi-walled carbon nanotubes in relation to their physicochemical properties

(2016) Henriqueta Louro et al.   TOXICOLOGY LETTERS

Cerium oxide nanoparticles in neuroprotection and considerations for efficacy and safety

(2016) Beverly A. Rzigalinski et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Nanoproducts – what is actually available to European consumers?

(2016) Steffen Foss Hansen et al.   Environmental Science-Nano

Acute and long-term in vitro effects of zinc oxide nanoparticles

(2015) Balasubramanyam Annangi et al.   ARCHIVES OF TOXICOLOGY

Antioxidant and anti-genotoxic properties of cerium oxide nanoparticles in a pulmonary-like cell system

(2015) Laura Rubio et al.   ARCHIVES OF TOXICOLOGY

Use of high-throughput RT-qPCR to assess modulations of gene expression profiles related to genomic stability and interactions by cadmium

(2015) Bettina Maria Fischer et al.   ARCHIVES OF TOXICOLOGY

Applications and Toxicity of Silver Nanoparticles: A Recent Review

(2015) Stefania Marin et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Combined exposure to nano-silica and lead induced potentiation of oxidative stress and DNA damage in human lung epithelial cells

(2015) Chun-Feng Lu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Toxicity assessment of aggregated/agglomerated cerium oxide nanoparticles in an in vitro 3D airway model: The influence of mucociliary clearance

(2015) C. Frieke Kuper et al.   TOXICOLOGY IN VITRO

Toxicological assessment of multi-walled carbon nanotubes on A549 human lung epithelial cells

(2015) Giuseppa Visalli et al.   TOXICOLOGY IN VITRO

Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory

(2015) Marina E Vance et al.   Beilstein Journal of Nanotechnology

Can the comet assay be used reliably to detect nanoparticle-induced genotoxicity?

(2014) Hanna L. Karlsson et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Evaluation of cytotoxic, genotoxic and inflammatory response in human alveolar and bronchial epithelial cells exposed to titanium dioxide nanoparticles

(2014) Cinzia Lucia Ursini et al.   JOURNAL OF APPLIED TOXICOLOGY

Applications of the comet assay in particle toxicology: air pollution and engineered nanomaterials exposure

(2014) P. Moller et al.   MUTAGENESIS

Long-term exposures to low doses of titanium dioxide nanoparticles induce cell transformation, but not genotoxic damage in BEAS-2B cells

(2014) Gerard Vales et al.   Nanotoxicology

Is the toxic potential of nanosilver dependent on its size?

(2014) Anna Huk et al.   Particle and Fibre Toxicology

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

(2014) Anda R Gliga et al.   Particle and Fibre Toxicology

Differences in Cytotoxic, Genotoxic, and Inflammatory Response of Bronchial and Alveolar Human Lung Epithelial Cells to Pristine and COOH-Functionalized Multiwalled Carbon Nanotubes

(2014) Cinzia Lucia Ursini et al.   Biomed Research International

The essential comet assay: a comprehensive guide to measuring DNA damage and repair

(2013) Amaya Azqueta et al.   ARCHIVES OF TOXICOLOGY

The comet assay as a tool for human biomonitoring studies: The ComNet Project

(2013) Andrew Collins et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Titanium dioxide nanoparticles: a review of current toxicological data

(2013) Hongbo Shi et al.   Particle and Fibre Toxicology

Intracellular Uptake and Toxicity of Ag and CuO Nanoparticles: A Comparison Between Nanoparticles and their Corresponding Metal Ions

(2013) Pontus Cronholm et al.   Small

Oxidative DNA damage corresponds to the long term survival of human cells treated with silver nanoparticles

(2013) Marcin Kruszewski et al.   TOXICOLOGY LETTERS

DNA Damage Caused by Metal Nanoparticles: Involvement of Oxidative Stress and Activation of ATM

(2012) Rong Wan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges

(2012) Helinor Johnston et al.   CRITICAL REVIEWS IN TOXICOLOGY

Multi-walled carbon nanotubes induce cytotoxicity and genotoxicity in human lung epithelial cells

(2012) Delia Cavallo et al.   JOURNAL OF APPLIED TOXICOLOGY

Genotoxicity of short single-wall and multi-wall carbon nanotubes in human bronchial epithelial and mesothelial cells in vitro

(2012) Hanna K. Lindberg et al.   TOXICOLOGY

Genotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in BEAS 2B cells

(2012) Penny Nymark et al.   TOXICOLOGY

Comparative cyto-genotoxicity assessment of functionalized and pristine multiwalled carbon nanotubes on human lung epithelial cells

(2012) Cinzia Lucia Ursini et al.   TOXICOLOGY IN VITRO

Genotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cells

(2011) Ha Ryong Kim et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

(2011) Mary-Line Jugan et al.   Nanotoxicology

Exploring the aneugenic and clastogenic potential in the nanosize range: A549 human lung carcinoma cells and amorphous monodisperse silica nanoparticles as models

(2010) Laetitia Gonzalez et al.   Nanotoxicology

A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro

(2010) Tina Thurnherr et al.   TOXICOLOGY LETTERS

NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials

(2009) Neenu Singh et al.   BIOMATERIALS

Genotoxic effects of nanosized and fine TiO2

(2009) GCM Falck et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Titanium dioxide nanoparticles induce oxidative stress and DNA-adduct formation but not DNA-breakage in human lung cells

(2009) Kunal Bhattacharya et al.   Particle and Fibre Toxicology

Mechanisms Related to the Genotoxicity of Particles in the Subway and from Other Sources

(2008) Hanna L. Karlsson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

DNA oxidation: Investigating its key role in environmental mutagenesis with the comet assay

(2008) Amaya Azqueta et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS