Article
Nanoscience & Nanotechnology
Yuemei Li, Yongmei Li, Haoming Wang, Riyue Liu
Summary: Yb/Er/CeO2-x upconversion nanoparticles have shown promising antioxidative activities in the treatment of Parkinson's disease, with increased enzyme-like catalytic activities and reductions in ROS production in the brain, indicating their potential as a therapeutic option for PD.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Naseer Ahmad, Sufian Rasheed, Muhammad Ikram Nabeel, Waqas Ahmad, Abrar Mohyuddin, Syed Ghulam Musharraf, Muhammad Najam-ul-Haq, Zafar Khan Ghouri, Dilshad Hussain
Summary: In this study, a fluorine-free, durable superhydrophobic cotton fabric with CeO2 nanoparticles and stearic acid was developed to mimic the lotus effect. The modified fabric exhibited high superhydrophobicity, self-cleaning, antiwater absorption, UV-blocking, and antibacterial properties. The proposed strategy is simple, green, economical, and has potential for commercial applications in functional fabric preparation.
Review
Biochemistry & Molecular Biology
Somu Yadav, Shivangi Chamoli, Piyush Kumar, Pawan Kumar Maurya
Summary: Cerium oxide nanoparticles have wide applications in biomedical fields, but their safety and biocompatibility pose challenges. Polysaccharides can be used as coatings for cerium oxide nanoparticles, affecting their properties. This review explores the impact of biopolymer coatings on size, stability, aggregation, and biocompatibility of cerium oxide nanoparticles, as well as their applications in bone tissue regeneration, liver inflammation, wound healing, and antibacterial and anticancer activities. Biocompatible cerium oxide nanoparticles will enhance their biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Adrian Boey, Shu Qing Leong, Sayali Bhave, Han Kiat Ho
Summary: Exposure to metallic nanoparticles can lead to unintended accumulation in body tissues, with cerium oxide nanoparticles showing potential beneficial effects by reducing oxidative stress levels and TGF-beta-mediated signaling in liver cells. These findings suggest a therapeutic pathway for hepatic fibrosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Valentina A. Petrova, Natallia V. Dubashynskaya, Iosif V. Gofman, Alexey S. Golovkin, Alexander I. Mishanin, Arthur D. Aquino, Daria V. Mukhametdinova, Alexandra L. Nikolaeva, Elena M. Ivan'kova, Alexander E. Baranchikov, Alexander V. Yakimansky, Vladimir K. Ivanov, Yury A. Skorik
Summary: Polymeric nanocomposite materials have the potential to enhance tissue-engineered scaffolds by influencing the structure and properties of polymeric materials and regulating cell behavior. In this study, cerium oxide nanoparticles were incorporated into a chitosan film to promote the proliferation of mesenchymal stem cells. The resulting CS-CeONP films exhibited good biocompatibility and regenerative potential in both in vitro and in vivo experiments.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Farah Quddus, Afzal Shah, Jan Nisar, Muhammad Abid Zia, Shamsa Munir
Summary: This research investigates the photocatalytic degradation of piroxicam and naproxen using CeO2 nanoparticles synthesized from Azadirachta indica plant extract. The results showed that the nanoparticles efficiently removed the pharmaceutical drugs with photodegradation efficiencies of 89% and 97% for naproxen and piroxicam, respectively. The photocatalytic process followed pseudo-order first-order kinetics, and the catalyst showed good recyclability with a degradation efficiency of 100% up to the 2nd cycle.
Article
Medicine, Research & Experimental
Fereshteh Asgharzadeh, Alireza Hashemzadeh, Farzad Rahmani, Atieh Yaghoubi, Seyedeh Elnaz Nazari, Amir Avan, Seyed Mahdi Hasanian Mehr, Saman Soleimanpour, Majid Khazaei
Summary: The experimental study demonstrated that cerium oxide nanoparticles significantly reduced clinical symptoms of colitis, enhanced disease activity index, and effectively reduced tissue damage, suggesting a promising therapeutic effect in treating ulcerative colitis.
Article
Cell Biology
Nikita N. Chukavin, Vladimir K. Ivanov, Anton L. Popov
Summary: This study investigated a new type of cerium oxide nanoparticles that can monitor intracellular reactive oxygen species (ROS) activity by releasing fluorescent dye calcein. The results show that these nanoparticles have selective cytotoxicity against cancer cells and can modulate the expression of key genes related to cell redox status and proliferation/migration activity.
Article
Polymer Science
Vasily V. Spiridonov, Andrey V. Sybachin, Vladislava A. Pigareva, Mikhail I. Afanasov, Sharifjon A. Musoev, Alexander V. Knotko, Sergey B. Zezin
Summary: An elegant method for synthesizing nanocomposites consisting of cerium-containing nanoparticles stabilized by carboxymethyl cellulose (CMC) macromolecules at room temperature was introduced in this study. The nanocomposites were characterized using microscopy, XRD, and IR spectroscopy analysis. The crystal structure of the inorganic nanoparticles, corresponding to CeO2, was determined and a mechanism for nanoparticle formation was proposed. The study demonstrated that the size and shape of the nanoparticles in the resulting nanocomposites were independent of the ratio of the initial reagents. Spherical particles with a mean diameter of 2-3 nm were obtained in different reaction mixtures with a cerium mass fraction ranging from 6.4% to 14.1%. The study also proposed a dual stabilization scheme for CeO2 nanoparticles involving carboxylate and hydroxyl groups of CMC. These findings suggest that the easily reproducible technique has promise for the large-scale development of nanoceria-containing materials.
Article
Chemistry, Applied
Mangala Joshi, Raman Sandhoo, Bapan Adak
Summary: This study investigates the effect of nano-ceria and nano-zirconia particles on the weather resistance property of polyurethane coatings. The results show that both nano-ceria and nano-zirconia have the potential to enhance the weather resistance performance of PU-coated fabrics, and the weather resistance improves gradually with increasing nanoparticle concentration. Nano-ceria has a better effect on improving weather resistance compared to nano-zirconia, especially at higher concentrations.
PROGRESS IN ORGANIC COATINGS
(2022)
Article
Chemistry, Multidisciplinary
Belal Hanafy, Gareth W. Cave, Yvonne Barnett, Barbara K. Pierscionek
Summary: Nanoceria delays cataract progression through multiple mechanisms including mimicking catalase, improving cellular redox state, and inhibiting glucose-induced glycation of lens proteins.
Article
Environmental Sciences
Arkajyoti Sarkar, Tharun Selvam Mahendran, Aasha Meenakshisundaram, Rushenka Vashti Christopher, Pallavi Dan, Vignesh Sundararajan, Nishant Jana, Devanand Venkatasubbu, Sahabudeen Sheik Mohideen
Summary: The study showed that exposure to BPA can lead to behavioral deficits and increased oxidative stress in flies, while co-treatment with cerium oxide nanoparticles can alleviate these negative effects.
Article
Nanoscience & Nanotechnology
Feng Li, Jian Li, Xujun Song, Tong Sun, Lian Mi, Jian Liu, Xiaomin Xia, Na Bai, Xue Li
Summary: This study developed and evaluated an appropriate GA-nCeO2 hydrogel scaffold for bone tissue engineering. The results showed that the scaffold had a favorable structure, biocompatibility, and strong osteogenic potential. This research provides a potential new material for the treatment of bone defects.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Environmental Sciences
Ajith Dias Samarajeewa, Jessica R. Velicogna, Dina M. Schwertfeger, Matthew J. Meier, Renuka M. Subasinghe, Juliska I. Princz, Rick P. Scroggins, Lee A. Beaudette
Summary: Increased use of nano-cerium oxide (nCeO(2)) in industrial applications has raised concerns about its potential effects on the soil microbial community. This research found that nCeO(2) did not consistently inhibit critical microbial processes such as organic matter decomposition and nitrification. However, soluble Ce had significant effects on these processes, indicating that the behavior of nCeO(2) differs from soluble Ce. This study provides valuable information for understanding the behavior and effects of nCeO(2).
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Polymer Science
Danil D. Kolmanovich, Nikita N. Chukavin, Irina V. Savintseva, Elena A. Mysina, Nelli R. Popova, Alexander E. Baranchikov, Madina M. Sozarukova, Vladimir K. Ivanov, Anton L. Popov
Summary: Layer-by-layer self-assembled polyelectrolyte capsules have great potential in drug delivery and imaging contrast agent applications. This study presents the design of MRI-visible capsules loaded with gadolinium-doped cerium oxide nanoparticles, which showed high biocompatibility and cellular uptake efficiency in cancer cells and normal cells.
Article
Toxicology
Sophia M. Orbach, Margaret E. Cassin, Marion F. Ehrich, Padmavathy Rajagopalan
TOXICOLOGY IN VITRO
(2017)
Article
Biochemical Research Methods
Yongle Du, Long Xia, Ami Jo, Richey M. Davis, Philippe Bissel, Marion F. Ehrich, David G. I. Kingston
BIOCONJUGATE CHEMISTRY
(2018)
Article
Engineering, Biomedical
Zongmin Zhao, Brian Harris, Yun Hu, Theresa Harmon, Paul R. Pentel, Marion Ehrich, Chenming Zhang
Article
Nanoscience & Nanotechnology
Zongmin Zhao, Yun Hu, Theresa Harmon, Paul R. Pentel, Marion Ehrich, Chenming Zhang
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2018)
Article
Toxicology
Sophia M. Orbach, Marion F. Ehrich, Padmavathy Rajagopalan
TOXICOLOGY IN VITRO
(2018)
Article
Engineering, Biomedical
Yun Hu, Zongmin Zhao, Theresa Harmon, Paul R. Pentel, Marion Ehrich, Chenming Zhang
Article
Pharmacology & Pharmacy
Andrew Leber, Raquel Hontecillas, Victoria Zoccoli-Rodriguez, Marion Ehrich, Jennifer Davis, Jyoti Chauhan, Josep Bassaganya-Riera
INTERNATIONAL JOURNAL OF TOXICOLOGY
(2019)
Article
Medicine, Research & Experimental
Zongmin Zhao, Yun Hu, Theresa Harmon, Paul Pentel, Marion Ehrich, Chenming Zhang
MOLECULAR PHARMACEUTICS
(2019)
Article
Nanoscience & Nanotechnology
Yun Hu, Daniel Smith, Zongmin Zhao, Theresa Harmon, Paul R. Pentel, Marion Ehrich, Chenming Zhang
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2019)
Article
Chemistry, Multidisciplinary
Andrew Leber, Raquel Hontecillas, Victoria Zoccoli-Rodriguez, Marion Ehrich, Jyoti Chauhan, Josep Bassaganya-Riera
Summary: The study found that NX-13 is safe and well-tolerated in rats at oral doses as high as 1000 mg/kg. No significant changes were observed in weight, clinical signs, blood parameters, or tissue pathology between treated and control rats. Pharmacokinetic analysis showed that NX-13 has a favorable gastrointestinal localized profile.
DRUG AND CHEMICAL TOXICOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Geraldine Magnin, Philippe Bissel, Roberto Mcalister Council-Troche, Zhiguo Zhou, Marion Ehrich
Article
Pharmacology & Pharmacy
Marion Ehrich, Jonathan Hinckley, Stephen R. Werre, Zhiguo Zhou
Article
Nanoscience & Nanotechnology
Yun Hu, Zongmin Zhao, Marion Ehrich, Chenming Zhang
Summary: Nicotine vaccines have been studied for smoking cessation, and the combination of lipid-PLA and lipid-PLGA nanoparticles has shown potential for achieving long-lasting immunity against nicotine. The results suggest that the stability and combination of vaccines play a crucial role in their long-term efficacy, with the lipid-PLA vaccine inducing more sustained antibody production. Additionally, the study indicated that the vaccines were safe for use in mice based on body weight and histopathology assessments.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Christine M. DuChane, George W. Karpin, Marion Enrich, Joseph O. Falkinham, Joseph S. Merola