TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis
Published 2016 View Full Article
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Title
TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis
Authors
Keywords
Musculoskeletal injury, Rotator cuff muscles, Fibrosis, Apoptosis, Mouse models, Signal inhibition, Histology, Muscle cells
Journal
PLoS One
Volume 11, Issue 5, Pages e0155486
Publisher
Public Library of Science (PLoS)
Online
2016-05-18
DOI
10.1371/journal.pone.0155486
References
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Related references
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- (2015) Michael R. Davies et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors
- (2015) Dario R Lemos et al. NATURE MEDICINE
- Factors Affecting Rotator Cuff Healing
- (2014) Nathan A Mall et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Prognostic Factors for Successful Recovery After Arthroscopic Rotator Cuff Repair: A Systematic Literature Review
- (2014) Anouk J.M. Fermont et al. JOURNAL OF ORTHOPAEDIC & SPORTS PHYSICAL THERAPY
- Upregulation of transforming growth factor-β signaling in a rat model of rotator cuff tears
- (2014) Xuhui Liu et al. JOURNAL OF SHOULDER AND ELBOW SURGERY
- Identification and characterization of PDGFRα+ mesenchymal progenitors in human skeletal muscle
- (2014) A Uezumi et al. Cell Death & Disease
- Roles of nonmyogenic mesenchymal progenitors in pathogenesis and regeneration of skeletal muscle
- (2014) Akiyoshi Uezumi et al. Frontiers in Physiology
- The Societal and Economic Value of Rotator Cuff Repair
- (2013) Richard C. Mather et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- Aging-associated exacerbation in fatty degeneration and infiltration after rotator cuff tear
- (2013) Jonathan P. Gumucio et al. JOURNAL OF SHOULDER AND ELBOW SURGERY
- A Mouse Model of Massive Rotator Cuff Tears
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- Rotator cuff tear reduces muscle fiber specific force production and induces macrophage accumulation and autophagy
- (2012) Jonathan P. Gumucio et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- mTOR regulates fatty infiltration through SREBP-1 and PPARγ after a combined massive rotator cuff tear and suprascapular nerve injury in rats
- (2012) Sunil K. Joshi et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Evaluation of Akt/mTOR activity in muscle atrophy after rotator cuff tears in a rat model
- (2012) Xuhui Liu et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- PAI-1 in tissue fibrosis
- (2011) Asish K. Ghosh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The effect of tear size and nerve injury on rotator cuff muscle fatty degeneration in a rodent animal model
- (2011) H. Mike Kim et al. JOURNAL OF SHOULDER AND ELBOW SURGERY
- Rotator cuff re-tear or non-healing: histopathological aspects and predictive factors
- (2011) C. Chillemi et al. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
- Transforming growth factor-beta induces skeletal muscle atrophy and fibrosis through the induction of atrogin-1 and scleraxis
- (2011) Christopher L. Mendias et al. MUSCLE & NERVE
- Role of TGF-β signaling in inherited and acquired myopathies
- (2011) Tyesha N Burks et al. Skeletal Muscle
- Regulation and dysregulation of fibrosis in skeletal muscle
- (2010) Antonio L. Serrano et al. EXPERIMENTAL CELL RESEARCH
- Development of Fatty Atrophy After Neurologic and Rotator Cuff Injuries in an Animal Model of Rotator Cuff Pathology
- (2010) Kasra Rowshan et al. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
- A rat model of massive rotator cuff tears
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- Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle
- (2010) Akiyoshi Uezumi et al. NATURE CELL BIOLOGY
- Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
- (2010) Aaron W. B. Joe et al. NATURE CELL BIOLOGY
- Prognostic Factors Affecting Anatomic Outcome of Rotator Cuff Repair and Correlation With Functional Outcome
- (2008) Joo Han Oh et al. ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
- Adipogenic and myogenic gene expression in rotator cuff muscle of the sheep after tendon tear
- (2008) Eric Frey et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Expression of transforming growth factor β isoforms and their roles in tendon healing
- (2008) Kai-Ming Chan et al. WOUND REPAIR AND REGENERATION
- Transforming growth factor-β and myostatin signaling in skeletal muscle
- (2007) Helen D. Kollias et al. JOURNAL OF APPLIED PHYSIOLOGY
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