Berberine Ameliorates Spatial Learning Memory Impairment and Modulates Cholinergic Anti-Inflammatory Pathway in Diabetic Rats

Berberine attenuates nonalcoholic hepatic steatosis through the AMPK-SREBP-1c-SCD1 pathway

(2019) Xiaopeng Zhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Systemic inflammation without gliosis mediates cognitive deficits through impaired BDNF expression in bile duct ligation model of hepatic encephalopathy

(2018) Saurabh Dhanda et al.   BRAIN BEHAVIOR AND IMMUNITY

Polyphenols and Bioavailability: an update

(2018) Hui Teng et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

GTS-21 Protected Against LPS-Induced Sepsis Myocardial Injury in Mice Through α7nAChR

(2018) Weilan Kong et al.   INFLAMMATION

α7 nicotinic acetylcholine receptors are involved in suppression of the antibody immune response

(2018) Lyudmyla Koval et al.   JOURNAL OF NEUROIMMUNOLOGY

Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats

(2018) Y. Yu et al.   Journal of Nutrition Health & Aging

Dietary triterpenes in the treatment of type 2 diabetes: To date

(2018) Hui Teng et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Genesis of Neuroprotective Peptoid from Aβ30–34 Inhibits Aβ Aggregation and AChE Activity

(2018) Krishnangsu Pradhan et al.   ACS Chemical Neuroscience

Diabetes-related cardiomyopathy: The sweet story of glucose overload from epidemiology to cellular pathways

(2018) M. Joubert et al.   DIABETES & METABOLISM

Type 2 Diabetes and Cognitive Impairment: Linking Mechanisms

(2018) José A. Luchsinger   JOURNAL OF ALZHEIMERS DISEASE

Cannabis-Based Medicine Reduces Multiple Pathological Processes in AβPP/PS1 Mice

(2018) Ester Aso et al.   JOURNAL OF ALZHEIMERS DISEASE

Berberine Alleviates Tau Hyperphosphorylation and Axonopathy-Associated with Diabetic Encephalopathy via Restoring PI3K/Akt/GSK3β Pathway

(2018) Shanshan Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Mechanisms of Insulin Action and Insulin Resistance

(2018) Max C. Petersen et al.   PHYSIOLOGICAL REVIEWS

Non-coding RNAs and Berberine: A new mechanism of its anti-diabetic activities

(2017) Wenguang Chang   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-inflammatory effects of astroglial α7 nicotinic acetylcholine receptors are mediated by inhibition of the NF-κB pathway and activation of the Nrf2 pathway

(2017) Hiral Patel et al.   Journal of Neuroinflammation

Antidiabetic Polypill Improves Central Pathology and Cognitive Impairment in a Mixed Model of Alzheimer’s Disease and Type 2 Diabetes

(2017) Carmen Infante-Garcia et al.   MOLECULAR NEUROBIOLOGY

Nicotinic Acetylcholine Receptor Alpha7 Subunit Mediates Vagus Nerve Stimulation-Induced Neuroprotection in Acute Permanent Cerebral Ischemia by a7nAchR/JAK2 Pathway

(2017) Xin-xin Lu et al.   MEDICAL SCIENCE MONITOR

Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation of Aberrant Inflammation Response and Insulin Signaling Pathway in DM Rats

(2017) Qingjie Chen et al.   Frontiers in Pharmacology

3D compartmented model to study the neurite-related toxicity of Aβ aggregates included in collagen gels of adaptable porosity

(2016) Marie-Noëlle Labour et al.   Acta Biomaterialia

Alzheimer's disease: Targeting the Cholinergic System

(2016) Talita H. Ferreira-Vieira et al.   Current Neuropharmacology

Expression and Functional Role of α7 Nicotinic Receptor in Human Cytokine-stimulated Natural Killer (NK) Cells

(2016) Samanta R. Zanetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blood–brain barrier breakdown promotes macrophage infiltration and cognitive impairment in leptin receptor-deficient mice

(2016) Alexis M Stranahan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Berberine relieves insulin resistance via the cholinergic anti-inflammatory pathway in HepG2 cells

(2016) Fen Li et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Immunomodulatory effects of nicotine on interleukin 1β activated human astrocytes and the role of cyclooxygenase 2 in the underlying mechanism

(2016) Priya Revathikumar et al.   Journal of Neuroinflammation

Effects of a physical fitness program on memory and blood viscosity in sedentary elderly men

(2015) H.K. Antunes et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Signaling from Glia and Cholinergic Neurons Controls Nutrient-Dependent Production of an Insulin-like Peptide for Drosophila Body Growth

(2015) Naoki Okamoto et al.   DEVELOPMENTAL CELL

Current knowledge and pharmacological profile of berberine: An update

(2015) Anil Kumar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Astrocyte barriers to neurotoxic inflammation

(2015) Michael V. Sofroniew   NATURE REVIEWS NEUROSCIENCE

Donepezil improves learning and memory deficits in APP/PS1 mice by inhibition of microglial activation

(2015) H.B. Guo et al.   NEUROSCIENCE

Therapeutic potential of berberine against neurodegenerative diseases

(2015) WenXiao Jiang et al.   Science China-Life Sciences

α7 Nicotinic Acetylcholine Receptor is a Novel Mediator of Sinomenine Anti-Inflammation Effect in Macrophages Stimulated by Lipopolysaccharide

(2015) Lang Yi et al.   SHOCK

α7 Nicotinic Receptor Promotes the Neuroprotective Functions of Astrocytes against Oxaliplatin Neurotoxicity

(2015) Lorenzo Di Cesare Mannelli et al.   NEURAL PLASTICITY

Alzheimer’s disease and type 2 diabetes via chronic inflammatory mechanisms

(2015) Gohar Mushtaq et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Alzheimer’s Disease and Type 2 Diabetes: Multiple Mechanisms Contribute to Interactions

(2014) Anusha Jayaraman et al.   Current Diabetes Reports

Activation of α7nAChR by Nicotine Reduced the Th17 Response in CD4+T Lymphocytes

(2014) Zhigang Liu et al.   IMMUNOLOGICAL INVESTIGATIONS

Type 2 Diabetes and Cognitive Impairment

(2014) John P. Ryan et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Blood Viscosity in Subcortical Vascular Mild Cognitive Impairment with versus without Cerebral Amyloid Burden

(2014) Hyun J. Noh et al.   Journal of Stroke & Cerebrovascular Diseases

Changes in the brain and plasma Aβ peptide levels with age and its relationship with cognitive impairment in the APPswe/PS1dE9 mouse model of Alzheimer’s disease

(2014) M. Izco et al.   NEUROSCIENCE

Diabetes and the Brain: Oxidative Stress, Inflammation, and Autophagy

(2014) María Muriach et al.   Oxidative Medicine and Cellular Longevity

High-sugar diets, type 2 diabetes and Alzheimerʼs disease

(2013) Paula I. Moreira   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth

(2013) Ya-Yun Hsu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Increased Aβ production prompts the onset of glucose intolerance and insulin resistance

(2012) Margarita Jiménez-Palomares et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Metabolic Alterations Induced by Sucrose Intake and Alzheimer’s Disease Promote Similar Brain Mitochondrial Abnormalities

(2012) Cristina Carvalho et al.   DIABETES

Chronic Exposure to Nicotine Enhances Insulin Sensitivity through α7 Nicotinic Acetylcholine Receptor-STAT3 Pathway

(2012) Tian-Ying Xu et al.   PLoS One

Role of Cyclophilin A from Brains of Prion-infected Mice in Stimulation of Cytokine Release by Microglia and Astrogliain Vitro

(2011) Déborah Tribouillard-Tanvier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

(2011) Mikko Hiltunen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients with type 2 diabetes mellitus

(2011) Maria Luiza Mendonça Pereira Jorge et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Blood rheology and cognition in the Edinburgh Type 2 Diabetes Study

(2010) R. E. Marioni et al.   AGE AND AGEING

TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling

(2010) Maren Amasheh et al.   JOURNAL OF CELL SCIENCE

Berberine suppresses proinflammatory responses through AMPK activation in macrophages

(2009) Hyun Woo Jeong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Protective effect of berberine on beta cells in streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats

(2009) Jiyin Zhou et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Impaired insulin secretion increases the risk of Alzheimer disease

(2008) E. Ronnemaa et al.   NEUROLOGY