Antidiabetic Polypill Improves Central Pathology and Cognitive Impairment in a Mixed Model of Alzheimer’s Disease and Type 2 Diabetes

Long-Term Metformin Usage and Cognitive Function among Older Adults with Diabetes

(2018) Tze Pin Ng et al.   JOURNAL OF ALZHEIMERS DISEASE

Simvastatin ameliorates memory impairment and neurotoxicity in streptozotocin-induced diabetic mice

(2017) Shun-Chang Fang et al.   NEUROSCIENCE

Vascular complications in diabetes: Microparticles and microparticle associated microRNAs as active players

(2016) Nicoleta Alexandru et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Angiotensin converting enzyme serum activities: Relationship with Alzheimer’s disease

(2016) Shan Zhuang et al.   BRAIN RESEARCH

Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice

(2016) Wilma Helena Oliveira et al.   BRAIN RESEARCH

Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers reduced dementia risk in patients with diabetes mellitus and hypertension

(2016) Yi-Chun Kuan et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Metformin Facilitates Amyloid-β Generation by β- and γ-Secretases via Autophagy Activation

(2016) Sung Min Son et al.   JOURNAL OF ALZHEIMERS DISEASE

Angiotensin Converting Enzyme Inhibitors Ameliorate Brain Inflammation Associated with Microglial Activation: Possible Implications for Alzheimer’s Disease

(2016) Nofar Torika et al.   Journal of Neuroimmune Pharmacology

Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy

(2016) Erica Barini et al.   Molecular Neurodegeneration

Long-term central pathology and cognitive impairment are exacerbated in a mixed model of Alzheimer’s disease and type 2 diabetes

(2016) Carmen Infante-Garcia et al.   PSYCHONEUROENDOCRINOLOGY

Quantification of simvastatin in mice plasma by near-infrared and chemometric analysis of spectral data

(2016) Usama Fahmy   Drug Design Development and Therapy

Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-κB activation: Use of insulin to attenuate metformin's effect

(2015) Pasquale Picone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Increased Spontaneous Central Bleeding and Cognition Impairment in APP/PS1 Mice with Poorly Controlled Diabetes Mellitus

(2015) Juan José Ramos-Rodriguez et al.   MOLECULAR NEUROBIOLOGY

Hypertension exacerbates predisposition to neurodegeneration and memory impairment in the presence of a neuroinflammatory stimulus: Protection by angiotensin converting enzyme inhibition

(2015) Ruby Goel et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease

(2015) Juan Jose Ramos-Rodriguez et al.   PSYCHONEUROENDOCRINOLOGY

Central Proliferation and Neurogenesis Is Impaired in Type 2 Diabetes and Prediabetes Animal Models

(2014) Juan Jose Ramos-Rodriguez et al.   PLoS One

Effects of Statins on Incident Dementia in Patients with Type 2 DM: A Population-Based Retrospective Cohort Study in Taiwan

(2014) Jui-Ming Chen et al.   PLoS One

The Anti-Diabetic Drug Metformin Reduces BACE1 Protein Level by Interfering with the MID1 Complex

(2014) Moritz M. Hettich et al.   PLoS One

The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy

(2013) Patrick L. McGeer et al.   ACTA NEUROPATHOLOGICA

Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin

(2013) E. M. Moore et al.   DIABETES CARE

Rapid β-Amyloid Deposition and Cognitive Impairment After Cholinergic Denervation in APP/PS1 Mice

(2013) Juan Jose Ramos-Rodriguez et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Selective benefits of simvastatin in bitransgenic APPSwe,Ind/TGF-β1 mice

(2013) Panayiota Papadopoulos et al.   NEUROBIOLOGY OF AGING

Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice

(2013) Juan Jose Ramos-Rodriguez et al.   PSYCHONEUROENDOCRINOLOGY

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Deregulation of Protein Phosphatase 2A and Hyperphosphorylation of   Protein Following Onset of Diabetes in NOD Mice

(2012) M.-A. Papon et al.   DIABETES

Effects of statins and cholesterol on memory functions in mice

(2012) Ravindra M. Ghodke et al.   METABOLIC BRAIN DISEASE

Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice

(2012) Jiejie Li et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?

(2011) Sónia C. Correia et al.   AGEING RESEARCH REVIEWS

Cerebrovascular lesions induce transient  -amyloid deposition

(2011) M. Garcia-Alloza et al.   BRAIN

Metformin restores endothelial function in aorta of diabetic rats

(2011) Cristina M Sena et al.   BRITISH JOURNAL OF PHARMACOLOGY

Low Dose Aspirin Therapy Decreases Blood Glucose Levels but Does not Prevent Type I Diabetes-induced Bone Loss

(2011) Lindsay M. Coe et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease

(2011) Yi-Fei Dong et al.   FASEB JOURNAL

Reduction of Brain β-Amyloid (Aβ) by Fluvastatin, a Hydroxymethylglutaryl-CoA Reductase Inhibitor, through Increase in Degradation of Amyloid Precursor Protein C-terminal Fragments (APP-CTFs) and Aβ Clearance

(2010) Mitsuru Shinohara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin metabolism and the risk of Alzheimer disease: The Rotterdam Study

(2010) E. M. C. Schrijvers et al.   NEUROLOGY

Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling

(2010) E. Kickstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A  deposition in an Alzheimer mouse model with diabetes

(2010) S. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

White Matter Damage and the Effect of Matrix Metalloproteinases in Type 2 Diabetic Mice After Stroke

(2010) Jieli Chen et al.   STROKE

The Role of Metabolic Disorders in Alzheimer Disease and Vascular Dementia

(2009) Suzanne Craft   ARCHIVES OF NEUROLOGY

Association of Plasma Leptin Levels With Incident Alzheimer Disease and MRI Measures of Brain Aging

(2009) Wolfgang Lieb   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Statins Reduce the Neurofibrillary Tangle Burden in a Mouse Model of Tauopathy

(2009) Moran Boimel et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Effects of insulinic therapy on cognitive impairment in patients with Alzheimer disease and Diabetes Mellitus type-2

(2009) Massimiliano Plastino et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

(2008) Randy  Strong et al.   AGING CELL

An aspirin a day for Alzheimer's disease?

(2008) Paul S Aisen   LANCET NEUROLOGY

Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors

(2008) Raj N Kalaria et al.   LANCET NEUROLOGY

Amyloid beta oligomers induce impairment of neuronal insulin receptors

(2007) Wei-Qin Zhao et al.   FASEB JOURNAL