Cilostazol ameliorates high free fatty acid (FFA)-induced activation of NLRP3 inflammasome in human vascular endothelial cells

Vildagliptin inhibits high free fatty acid (FFA)-induced NLRP3 inflammasome activation in endothelial cells

(2019) Yanyan Qi et al.   Artificial Cells Nanomedicine and Biotechnology

Beneficial effects of Cilostazol on liver injury induced by common bile duct ligation in rats: Role of SIRT1 signaling pathway

(2018) Soad L Kabil   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Plasma levels of free fatty acids correlate with type 2 diabetes mellitus

(2018) Sandro Spiller et al.   DIABETES OBESITY & METABOLISM

Phosphodiesterase-3 inhibitor cilostazol reverses endothelial dysfunction with ageing in rat mesenteric resistance arteries

(2018) Hicla S. Moreira et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

NLRP3 inflammasome is expressed and regulated in human islets

(2018) Fanny Lebreton et al.   Cell Death & Disease

Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications

(2018) Arpeeta Sharma et al.   Frontiers in Physiology

Oxymatrine ameliorates diabetes-induced aortic endothelial dysfunction via the regulation of eNOS and NOX4

(2018) Lei Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pathophysiology of mitochondrial lipid oxidation: Role of 4-hydroxynonenal (4-HNE) and other bioactive lipids in mitochondria

(2017) Mengqing Xiao et al.   FREE RADICAL BIOLOGY AND MEDICINE

The lipid peroxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte

(2017) Bettina P. Mihalas et al.   Scientific Reports

The redox state of the alarmin HMGB1 is a pivotal factor in neuroinflammatory and microglial priming: A role for the NLRP3 inflammasome

(2016) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

The Role of HMGB1 in the Pathogenesis of Type 2 Diabetes

(2016) Yanan Wang et al.   Journal of Diabetes Research

New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats

(2016) Chunchun Ding et al.   Scientific Reports

Global Overview of the Epidemiology of Atherosclerotic Cardiovascular Disease

(2015) Simon Barquera et al.   ARCHIVES OF MEDICAL RESEARCH

Suppression of RANKL-induced osteoclast differentiation by cilostazol via SIRT1-induced RANK inhibition

(2015) So Youn Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Diabetic Cardiovascular Disease Induced by Oxidative Stress

(2015) Yosuke Kayama et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cilostazol inhibits HMGB1 release in LPS-activated RAW 264.7 cells and increases the survival of septic mice

(2015) Ki Churl Chang   THROMBOSIS RESEARCH

NLRP3 inflammasome and its inhibitors: a review

(2015) Bo-Zong Shao et al.   Frontiers in Pharmacology

Cilostazol Upregulates Autophagy via SIRT1 Activation: Reducing Amyloid-β Peptide and APP-CTFβ Levels in Neuronal Cells

(2015) Hye Rin Lee et al.   PLoS One

TXNIP mediates NLRP3 inflammasome activation in cardiac microvascular endothelial cells as a novel mechanism in myocardial ischemia/reperfusion injury

(2014) Yi Liu et al.   BASIC RESEARCH IN CARDIOLOGY

Free fatty acids as modulators of the NLRP3 inflammasome in obesity/type 2 diabetes

(2014) Sylvie Legrand-Poels et al.   BIOCHEMICAL PHARMACOLOGY

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

(2013) Islam N. Mohamed et al.   DIABETOLOGIA

Thioredoxin-interacting Protein Mediates High Glucose-induced Reactive Oxygen Species Generation by Mitochondria and the NADPH Oxidase, Nox4, in Mesangial Cells

(2013) Anu Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cilostazol prevents foot ulcers in diabetic patients with peripheral vascular disease

(2013) Stefano de Franciscis et al.   International Wound Journal

Anti-Inflammatory Role of Cilostazol in Vascular Smooth Muscle Cells In vitro and In vivo

(2011) Chie Aoki et al.   Journal of Atherosclerosis and Thrombosis

Inflammasome activation and IL-1β and IL-18 processing during infection

(2011) Frank L. van de Veerdonk et al.   TRENDS IN IMMUNOLOGY

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

(2010) J. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA